NEW APPROACH TO ADDRESSING GAS GENERATION IN RADIOACTIVE MATERIAL PACKAGING

Safety Analysis Reports for Packaging (SARP) document why the transportation of radioactive material is safe in Type A(F) and Type B shipping containers. The content evaluation of certain actinide materials require that the gas generation characteristics be addressed. Most packages used to transport actinides impose extremely restrictive limits on moisture content and oxide stabilization to control or prevent flammable gas generation. These requirements prevent some users from using a shipping container even though the material to be shipped is fully compliant with the remaining content envelope including isotopic distribution. To avoid these restrictions, gas generation issues have to be addressed on a case by case basis rather than a one size fits all approach. In addition, SARP applicants and review groups may not have the knowledge and experience with actinide chemistry and other factors affecting gas generation, which facility experts in actinide material processing have obtained in the last sixty years. This paper will address a proposal to create a Gas Generation Evaluation Committee to evaluate gas generation issues associated with Safety Analysis Reports for Packaging material contents. The committee charter could include reviews of both SARP approved contents and new contents not previously evaluated in a SARP

BFKL versus HERA

The BFKL equation and the kT-factorization theorem are used to obtain predictions for F2 in the small Bjorken-x region over a wide range of Q**2. The dependence on the parameters, especially on those concerning the infrared region, is discussed. After a background fit to recent experimental data obtained at HERA and at Fermilab (E665 experiment), we find that the predicted, almost Q**2 independent BFKL slope lambda >= 0.5 appears to be too steep at lower Q**2 values. Thus there seems to be a chance that future HERA data can distinguish between pure BFKL and conventional field theoretic renormalization group approaches.Comment: 26 pages, 6 eps figures, LaTeX2e using epsfig.sty and amssymb.st

Anatomy of the differential gluon structure function of the proton from the experimental data on F_2p

The use of the differential gluon structure function of the proton ${\cal F}(x,Q^{2})$ introduced by Fadin, Kuraev and Lipatov in 1975 is called upon in many applications of small-x QCD. We report here the first determination of ${\cal F}(x,Q^{2})$ from the experimental data on the small-x proton structure function $F_{2p}(x,Q^{2})$. We give convenient parameterizations for ${\cal F}(x,Q^{2})$ based partly on the available DGLAP evolution fits (GRV, CTEQ & MRS) to parton distribution functions and on realistic extrapolations into soft region. We discuss an impact of soft gluons on various observables. The x-dependence of the so-determined ${\cal F}(x,Q^{2})$ varies strongly with Q^2 and does not exhibit simple Regge properties. None the less the hard-to-soft diffusion is found to give rise to a viable approximation of the proton structure function F_{2p}(x,Q^2) by the soft and hard Regge components with intercepts \Delta_{soft}=0 and \Delta_{hard}\sim 0.4.Comment: 37 pages, 25 figure

Deep inelastic events containing a forward photon as a probe of small xx dynamics

We calculate the rate of producing deep inelastic events containing an energetic isolated forward photon at HERA. We quantify the enhancement arising from the leading $\log 1/x$ gluon emissions with a view to using such events to identify the underlying dynamics.Comment: 11 pages, Latex, 7 ps figure

A unified BFKL and GLAP description of F2F_2 data

We argue that the use of the universal unintegrated gluon distribution and the $k_T$ (or high energy) factorization theorem provides the natural framework for describing observables at small x. We introduce a coupled pair of evolution equations for the unintegrated gluon distribution and the sea quark distribution which incorporate both the resummed leading $ln (1/x)$ BFKL contributions and the resummed leading $ln (Q^2)$ GLAP contributions. We solve these unified equations in the perturbative QCD domain using simple parametic forms of the nonperturbative part of the integrated distributions. With only two (physically motivated) input parameters we find that this $k_T$ factorization approach gives an excellent description of the measurements of $F_2 (x,Q^2)$ at HERA. In this way the unified evolution equations allow us to determine the gluon and sea quark distributions and, moreover, to see the x domain where the resummed $ln (1/x)$ effects become significant. We use $k_T$ factorization to predict the longitudinal structure function $F_L (x,Q^2)$ and the charm component of $F_2 (x,Q^2)$.Comment: 25 pages, LaTeX, 9 figure

Interactions between the Nse3 and Nse4 Components of the SMC5-6 Complex Identify Evolutionarily Conserved Interactions between MAGE and EID Families

The SMC5-6 protein complex is involved in the cellular response to DNA damage. It is composed of 6-8 polypeptides, of which Nse1, Nse3 and Nse4 form a tight sub-complex. MAGEG1, the mammalian ortholog of Nse3, is the founding member of the MAGE (melanoma-associated antigen) protein family and Nse4 is related to the EID (E1A-like inhibitor of differentiation) family of transcriptional repressors.Using site-directed mutagenesis, protein-protein interaction analyses and molecular modelling, we have identified a conserved hydrophobic surface on the C-terminal domain of Nse3 that interacts with Nse4 and identified residues in its N-terminal domain that are essential for interaction with Nse1. We show that these interactions are conserved in the human orthologs. Furthermore, interaction of MAGEG1, the mammalian ortholog of Nse3, with NSE4b, one of the mammalian orthologs of Nse4, results in transcriptional co-activation of the nuclear receptor, steroidogenic factor 1 (SF1). In an examination of the evolutionary conservation of the Nse3-Nse4 interactions, we find that several MAGE proteins can interact with at least one of the NSE4/EID proteins.We have found that, despite the evolutionary diversification of the MAGE family, the characteristic hydrophobic surface shared by all MAGE proteins from yeast to humans mediates its binding to NSE4/EID proteins. Our work provides new insights into the interactions, evolution and functions of the enigmatic MAGE proteins

Core temperature responses to cold-water immersion recovery: A pooled-data analysis

© 2018 Human Kinetics, Inc. Purpose: To examine the effect of postexercise cold-water immersion (CWI) protocols, compared with control (CON), on the magnitude and time course of core temperature (Tc) responses. Methods: Pooled-data analyses were used to examine the Tc responses of 157 subjects from previous postexercise CWI trials in the authors’ laboratories. CWI protocols varied with different combinations of temperature, duration, immersion depth, and mode (continuous vs intermittent). Tc was examined as a double difference (ΔΔTc), calculated as the change in Tc in CWI condition minus the corresponding change in CON. The effect of CWI on ΔΔTc was assessed using separate linear mixed models across 2 time components (component 1, immersion; component 2, postintervention). Results: Intermittent CWI resulted in a mean decrease in ΔΔTc that was 0.25°C (0.10°C) (estimate [SE]) greater than continuous CWI during the immersion component (P = .02). There was a significant effect of CWI temperature during the immersion component (P = .05), where reductions in water temperature of 1°C resulted in decreases in ΔΔTc of 0.03°C (0.01°C). Similarly, the effect of CWI duration was significant during the immersion component (P = .01), where every 1 min of immersion resulted in a decrease in ΔΔTc of 0.02°C (0.01°C). The peak difference in Tc between the CWI and CON interventions during the postimmersion component occurred at 60 min postintervention. Conclusions: Variations in CWI mode, duration, and temperature may have a significant effect on the extent of change in Tc. Careful consideration should be given to determine the optimal amount of core cooling before deciding which combination of protocol factors to prescribe

Pitch then power: limitations to acceleration in quadrupeds

Rapid acceleration and deceleration are vital for survival in many predator and prey animals and are important attributes of animal and human athletes. Adaptations for acceleration and deceleration are therefore likely to experience strong selective pressures—both natural and artificial. Here, we explore the mechanical and physiological constraints to acceleration. We examined two elite athletes bred and trained for acceleration performance (polo ponies and racing greyhounds), when performing maximal acceleration (and deceleration for ponies) in a competitive setting. We show that maximum acceleration and deceleration ability may be accounted for by two simple limits, one mechanical and one physiological. At low speed, acceleration and deceleration may be limited by the geometric constraints of avoiding net nose-up or tail-up pitching, respectively. At higher speeds, muscle power appears to limit acceleration

Mutual heavy ion dissociation in peripheral collisions at ultrarelativistic energies

We study mutual dissociation of heavy nuclei in peripheral collisions at ultrarelativistic energies. Earlier this process was proposed for beam luminosity monitoring via simultaneous registration of forward and backward neutrons in zero degree calorimeters at Relativistic Heavy Ion Collider. Electromagnetic dissociation of heavy ions is considered in the framework of the Weizsacker-Williams method and simulated by the RELDIS code. Photoneutron cross sections measured in different experiments and calculated by the GNASH code are used as input for the calculations of dissociation cross sections. The difference in results obtained with different inputs provides a realistic estimation for the systematic uncertainty of the luminosity monitoring method. Contribution to simultaneous neutron emission due to grazing nuclear interactions is calculated within the abrasion model. Good description of CERN SPS experimental data on Au and Pb dissociation gives confidence in predictive power of the model for AuAu and PbPb collisions at RHIC and LHC.Comment: 46 pages with 7 tables and 13 figures, numerical integration accuracy improved, next-to-leading-order corrections include

Managing affect in learners' questions in undergraduate science

This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2012 Society for Research into Higher Education.This article aims to position students' classroom questioning within the literature surrounding affect and its impact on learning. The article consists of two main sections. First, the act of questioning is discussed in order to highlight how affect shapes the process of questioning, and a four-part genesis to question-asking that we call CARE is described: the construction, asking, reception and evaluation of a learner's question. This work is contextualised through studies in science education and through our work with university students in undergraduate chemistry, although conducted in the firm belief that it has more general application. The second section focuses on teaching strategies to encourage and manage learners' questions, based here upon the conviction that university students in this case learn through questioning, and that an inquiry-based environment promotes better learning than a simple ‘transmission’ setting. Seven teaching strategies developed from the authors' work are described, where university teachers ‘scaffold’ learning through supporting learners' questions, and working with these to structure and organise the content and the shape of their teaching. The article concludes with a summary of the main issues, highlighting the impact of the affective dimension of learning through questioning, and a discussion of the implications for future research