Rewards Satisfaction, Perception about Social Status and Commitment of Nurses in Pakistan

This research is undertaken to approve or reject the general perception of masses about commitment of employees and to identify those factors, which effect commitment of employees in general and of nurses in particular. In previous research of Allen and Myere (1990), the factor of social status was not addressed. In this study target audience is nurses. Whereas, it is a proven fact that psychological perception effects individual’s attitudes and behaviors, so to see that how satisfaction with rewards/ benefits and perception about social status effect commitment of employees, this research was undertaken. Satisfaction level varies from person to person. The empirical results have proved that commitment of employees is affected due to satisfaction with rewards/ benefits and perception about social status

Rewards Satisfaction, Perception about Social Status and Commitment of Nurses in Pakistan

This research is undertaken to approve or reject the general perception of masses about commitment of employees and to identify those factors, which effect commitment of employees in general and of nurses in particular. In previous research of Allen and Myere (1990), the factor of social status was not addressed. In this study target audience is nurses. Whereas, it is a proven fact that psychological perception effects individual’s attitudes and behaviors, so to see that how satisfaction with rewards/ benefits and perception about social status effect commitment of employees, this research was undertaken. Satisfaction level varies from person to person. The empirical results have proved that commitment of employees is affected due to satisfaction with rewards/ benefits and perception about social status

Presentation of Acute Lymphoblastic Lymphoma and Colorectal Carcinoma in the Context of Constitutional Mismatch Repair Deficiency Syndrome (CMMRD): a Case Report with Literature Review

Introduction: Constitutional mismatch repair deficiency (CMMRD) is a rare autosomal recessive disease-carrying an increased risk of cancers (pediatric tumors of central nervous system, haemato-lymphoid malignancies along with gastrointestinal (GI) cancer(s), which are usually seen in the second and third decade) leading to syndromic presentation. Causal mutations are detected in DNA mismatch repair (MMR) genes, including MLH1, PMS2, MSH2, and MSH6 that are also known for their established role in Lynch syndrome. We describe a case of CMMRD with an earlier (first decade of life) presentation of mediastinal acute lymphoblastic lymphoma and colorectal malignancy. Case Presentation: A five-year-old boy presented with respiratory complaints, bilateral cervical lymphadenopathy, multiple café au lait macules (CALMs) on the lower back, history of parental consanguinity with the death of three sisters due to brain tumor within 6 months of diagnosis. Computerized tomographic (CT) scan chest revealed a huge mediastinal mass. The patient underwent a trucut-biopsy of the mass. The results were significant for a pre T-cell acute lymphoblastic lymphoma. Suspicion of CMMRD was raised based on a combination of factors described above. A panel of mismatch repair (MMR) proteins was applied on the biopsy tissue that revealed loss of nuclear expression of MLH1 and PMS2 immunostaining in tumor cells with positive external controls. While on maintenance therapy for lymphoma, about a year later, the patient developed sub-acute intestinal obstruction due to a stenosing polypoidal circumferential tumor in the mid-sigmoid colon found on flexible sigmoidoscopy that was followed by endoscopic biopsies and insertion of a fully-covered self-expanding metallic adult biliary stent with a diameter of 10 mm and length of 6 cm leading to immediate relief of obstruction. Biopsies revealed adenocarcinoma with neuroendocrine differentiation. Metastatic tumor deposits were seen in the omentum, anterior abdominal wall, and the left peritoneal wall. Practical Implications: Earlier (first decade) presentation of gastrointestinal malignancy warrants that an earlier screening through radiological scans for any possible tumors and MMR protein expression analysis (loss in tumor plus normal non-tumor cells) are essential in patients having CALMs and family history of pediatric tumors

Degree of Hearing Loss in Association with Site of Tympanic Membrane Perforation: A Systematic Review

Background: Tympanic Membrane perforation is commonly seen in a middle ear pathology called chronic otitis media that affects at least 0.5% of the total world population. Aim: To evaluate the nature of hearing loss in tympanic membrane perforation (TMP) based on the site of perforation. Study design: Systemic review. Methodology: All the articles were taken from Google Scholar, Cochrane Library, Pub Med, NCBI (NLM Catalog) and HEC Digital Library within five years range: 2017-2021. All the researchers were screened widely by a well-intentioned peer review group. Results: Articles (n=19) were included in the review. In case of site of perforation, most of the articles compared anterior site with posterior and central, depicting that posterior site causes more hearing loss than anterior site, while central perforations had greater hearing loss than anterior/posterior site. The total sample size of these 19 articles collectively was (n=1,650). Most severe hearing loss with respect to site of TM perforation was demonstrated in only 1 study (5.26%) out of 19 and that was 61-80 decibels. One study (5.26%) showed no correlation between hearing loss and site of TM perforation. Practical Implication: Sometimes, it is seen in ENT practices that there was a dilemma regarding the severity of hearing loss with respect to site of perforation. It benefited otolaryngologists to find a systematic review on the provided topic, to learn and know more about the association between hearing loss and site of TMP. Conclusion: We concluded that anterior sites of perforations cause less hearing loss than posterior, central or marginal. Keywords: Hearing loss; Tympanic membrane perforation; Site of TM perforation.</jats:p

Theoretical Investigations of Lead-Free Halide Perovskites Na₂AgInY₆ (Y = Cl, Br, I) for Transport and Optoelectronic Devices

Lead-free double perovskites are stable, non-toxic, and have high conversion efficiency, better oxidation resistance, and high-temperature stability, making them promising for optoelectronic and thermoelectric materials. In the current report, we have examined structural, electronic, optical, and transport characteristics of Na2AgInY6 (Y = Cl, Br, I) utilizing DFT-based Wien2k code. Thermodynamic stability is verified by calculating the enthalpy of formation. TB-mBJ measures the bandgap computations, and the investigated compositions have indirect bandgaps. The bandgap values are decreased from 3.1 eV to 1.2 eV as the halide ion is replaced from Cl - I. This substitution-dependent tuning of band edge across the visible-infrared boundary makes them favorable for solar cell applications. The optical response is evaluated by measuring the refractive index, dielectric constant, absorption coefficient, and reflectivity. The thermoelectric efficiency of Na2AgInY6 (Y = Cl, Br, I) is calculated by figure of merit and power factor. The findings of this study unveil the potential of these novel compositions for next-generation energy harvesting devices, including solar cells and thermoelectric devices. (c) 2023 The Electrochemical Society ("ECS")

Presentation of Acute Lymphoblastic Lymphoma and Colorectal Carcinoma in the Context of Constitutional Mismatch Repair Deficiency Syndrome (CMMRD): a Case Report with Literature Review

Introduction: Constitutional mismatch repair deficiency (CMMRD) is a rare autosomal recessive disease-carrying an increased risk of cancers (pediatric tumors of central nervous system, haemato-lymphoid malignancies along with gastrointestinal (GI) cancer(s), which are usually seen in the second and third decade) leading to syndromic presentation. Causal mutations are detected in DNA mismatch repair (MMR) genes, including MLH1, PMS2, MSH2, and MSH6 that are also known for their established role in Lynch syndrome. We describe a case of CMMRD with an earlier (first decade of life) presentation of mediastinal acute lymphoblastic lymphoma and colorectal malignancy. Case Presentation: A five-year-old boy presented with respiratory complaints, bilateral cervical lymphadenopathy, multiple café au lait macules (CALMs) on the lower back, history of parental consanguinity with the death of three sisters due to brain tumor within 6 months of diagnosis. Computerized tomographic (CT) scan chest revealed a huge mediastinal mass. The patient underwent a trucut-biopsy of the mass. The results were significant for a pre T-cell acute lymphoblastic lymphoma. Suspicion of CMMRD was raised based on a combination of factors described above. A panel of mismatch repair (MMR) proteins was applied on the biopsy tissue that revealed loss of nuclear expression of MLH1 and PMS2 immunostaining in tumor cells with positive external controls. While on maintenance therapy for lymphoma, about a year later, the patient developed sub-acute intestinal obstruction due to a stenosing polypoidal circumferential tumor in the mid-sigmoid colon found on flexible sigmoidoscopy that was followed by endoscopic biopsies and insertion of a fully-covered self-expanding metallic adult biliary stent with a diameter of 10 mm and length of 6 cm leading to immediate relief of obstruction. Biopsies revealed adenocarcinoma with neuroendocrine differentiation. Metastatic tumor deposits were seen in the omentum, anterior abdominal wall, and the left peritoneal wall. Practical Implications: Earlier (first decade) presentation of gastrointestinal malignancy warrants that an earlier screening through radiological scans for any possible tumors and MMR protein expression analysis (loss in tumor plus normal non-tumor cells) are essential in patients having CALMs and family history of pediatric tumors.</jats:p

Tensile and wear properties of repetitive corrugation and straightened Al 2024 alloy: an experimental and RSM approach

Abstract Repetitive Corrugation and Straightening (RCS) on sheet geometries causes Cyclic Plastic Deformation, resulting in potential improvements of mechanical characteristics in metals and alloys. In this study, sample sheets of Al 2024 are subjected to severe plastic deformation with specially designed corrugated rollers to generate heterogeneous repeated plastic deformation at room temperature. The material shows enhanced properties under severe plastic deformation, with 5.07% increase in tensile strength, compared to unprocessed material. Maximum tensile strength was observed at annealed temperature of 150 °C is of about 3.49% increase in tensile strength over other temperature conditions. A wear study was carried out by considering the processed sheet that yields high tensile strength (annealed at 150 °C) by varying process parameters like sliding distance, load and sliding velocity as per design of experiments. In comparison to all other combinations, the wear resistance was shown to be better with a sliding distance of 6000 m, a load of 9.81 N, and a sliding velocity of 1.45 m s−1. The Response Surface Methodology (RSM) approach was adopted for comparing purpose, the experimental findings are found to be more similar to the RSM approach’s outcomes.</jats:p

Factors affecting entrepreneurial intention for sustainable tourism among the students of higher education institutions

Entrepreneurs have an essential role to play in bringing positive change and growth to the world's economy. Entrepreneurship is a necessary aspect of economic growth because of its contribution to people's welfare through employment opportunities. Likewise, institutions of higher learning offer compulsory entrepreneurship courses for students with the support of government policies to encourage students towards entrepreneurship. Therefore, this study aimed to determine the factors influencing the students' intentions to become green entrepreneurs. The study uses the extended theory of planned behaviour model (TPB) and entrepreneurial education to develop a theoretical framework. The model has been examined on 350 tourism university students using structural equation modelling. The key findings indicate that Ajzen's TPB theory of planned behaviour and entrepreneurial education can be extensively expanded to determine sustainable entrepreneurial intentions in developing economies such as India. Attitude, subjective norms, perceived behavioural control, and entrepreneurial education are antecedents of entrepreneurial intent. Our results have valuable implications for aspiring entrepreneurs, policymakers, and scholars