Quantification of abnormal repetitive behaviour in captive European starlings (Sturnus vulgaris).

Stereotypies are repetitive, unvarying and goalless behaviour patterns that are often considered indicative of poor welfare in captive animals. Quantifying stereotypies can be difficult, particularly during the early stages of their development when behaviour is still flexible. We compared two methods for objectively quantifying the development of route-tracing stereotypies in caged starlings. We used Markov chains and T-pattern analysis (implemented by the software package, Theme) to identify patterns in the sequence of locations a bird occupied within its cage. Pattern metrics produced by both methods correlated with the frequency of established measures of stereotypic behaviour and abnormal behaviour patterns counted from video recordings, suggesting that both methods could be useful for identifying stereotypic individuals and quantifying stereotypic behaviour. We discuss the relative benefits and disadvantages of the two approaches

Relativistic Doppler effect in quantum communication

When an electromagnetic signal propagates in vacuo, a polarization detector cannot be rigorously perpendicular to the wave vector because of diffraction effects. The vacuum behaves as a noisy channel, even if the detectors are perfect. The ``noise'' can however be reduced and nearly cancelled by a relative motion of the observer toward the source. The standard definition of a reduced density matrix fails for photon polarization, because the transversality condition behaves like a superselection rule. We can however define an effective reduced density matrix which corresponds to a restricted class of positive operator-valued measures. There are no pure photon qubits, and no exactly orthogonal qubit states.Comment: 10 pages LaTe

Gravitating monopoles in SU(3) gauge theory

We consider the Einstein-Yang-Mills-Higgs equations for an SU(3) gauge group in a spherically symmetric ansatz. Several properties of the gravitating monopole solutions are obtained an compared with their SU(2) counterpart.Comment: 7 pages, Latex, 3 figure

KH 15D: A Spectroscopic Binary

We present the results of a high-resolution spectroscopic monitoring program of the eclipsing pre-main-sequence star KH 15D that reveal it to be a single-line spectroscopic binary. We find that the best-fit Keplerian model has a period P = 48.38 days, which is nearly identical to the photometric period. Thus, we find the best explanation for the periodic dimming of KH 15D is that the binary motion carries the currently visible star alternately above and below the edge of an obscuring cloud. The data are consistent with the models involving an inclined circumstellar disk, as recently proposed by Winn et al. (2004) and Chiang & Murray-Clay (2004). We show that the mass ratio expected from models of PMS evolution, together with the mass constraints for the visible star, restrict the orbital eccentricity to 0.68 < e < 0.80 and the mass function to 0.125 < Fm < 0.5 Msun.Comment: 8 pages, 4 figures, 3 tables, accepted for publication in September AJ. Discussion of rotational velocity deferred to Hamilton, et al. (2004, in prep). Previously reported vsini value in error; Replaced Table 3 with new Figure 3; Added new Table 2 showing individual radial velocities w.r.t. each reference star; Fixed typo in Figure

Rhythmic Oxygen Levels Reset Circadian Clocks through HIF1 alpha

This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this recordThe mammalian circadian system consists of a master clock in the brain that synchronizes subsidiary oscillators in peripheral tissues. The master clock maintains phase coherence in peripheral cells through systemic cues such as feeding-fasting and temperature cycles. Here, we examined the role of oxygen as a resetting cue for circadian clocks. We continuously measured oxygen levels in living animals and detected daily rhythms in tissue oxygenation. Oxygen cycles, within the physiological range, were sufficient to synchronize cellular clocks in a HIF1α-dependent manner. Furthermore, several clock genes responded to changes in oxygen levels through HIF1α. Finally, we found that a moderate reduction in oxygen levels for a short period accelerates the adaptation of wild-type but not of HIF1α-deficient mice to the new time in a jet lag protocol. We conclude that oxygen, via HIF1α activation, is a resetting cue for circadian clocks and propose oxygen modulation as therapy for jet lag.Israel Science FoundationEuropean Research CouncilFeinberg Graduate School, Weizmann Institute of ScienceBritish Heart FoundationEuropean Union, Seventh Framework Programm

Reliability and validity of the adapted Greek version of scoliosis research society – 22 (SRS-22) questionnaire

<p>Abstract</p> <p>Background</p> <p>The SRS-22 is a valid instrument for the assessment of the health related quality of life of patients with Idiopathic scoliosis. The SRS-22 questionnaire was developed in USA and has been widely used in the English speaking countries. Recently it has been translated and validated in many other languages. The purpose of this study is to evaluate the reliability and validity of the adapted Greek version of the refined Scoliosis Research Society-22 Questionnaire.</p> <p>Methods</p> <p>Following the steps of cross – cultural adaptation the adapted Greek version of the SRS-22 questionnaire and a validated Greek version of the SF-36 questionnaire were mailed to 68 patients treated surgically for Idiopathic Scoliosis. 51 out of the 68 patients returned the 1^stset of questionnaires, while a second set was emailed to 30 randomly selected patients of the first time responders. 20 out of the 30 patients returned the 2^ndset. The mean age at the time of operation was16,2 years and the mean age at the time of evaluation was 21,2 years. Descriptive statistics for content analysis were calculated. Reliability assessment was determined by estimating Cronbach's α and intraclass correlation coefficient (ICC) respectively. Concurrent validity was evaluated by comparing SRS-22 domains with relevant domains in the SF-36 questionnaire using Pearson's Correlation Coefficient (r).</p> <p>Results</p> <p>The calculated Cronbach's α of internal consistency for three of the corresponding domains (pain 0.85; mental health 0.87; self image 0.83) were very satisfactory and for two domains (function/activity 0.72 and satisfaction 0.67) were good. The ICC of all domains of SRS-22 questionnaire was high (ICC>0.70), demonstrating very satisfactory or excellent test/retest reproducibility. Considering concurrent validity all correlations were found to be statistically significant at the 0.01 level among related domains and generally demonstrated high correlation coefficient.</p> <p>Conclusion</p> <p>The adapted Greek version of the SRS-22 questionnaire is valid and reliable and can be used for the assessment of the outcome of the treatment of the Greek speaking patients with idiopathic scoliosis.</p

Stereotyping starlings are more 'pessimistic'.

Negative affect in humans and animals is known to cause individuals to interpret ambiguous stimuli pessimistically, a phenomenon termed 'cognitive bias'. Here, we used captive European starlings (Sturnus vulgaris) to test the hypothesis that a reduction in environmental conditions, from enriched to non-enriched cages, would engender negative affect, and hence 'pessimistic' biases. We also explored whether individual differences in stereotypic behaviour (repetitive somersaulting) predicted 'pessimism'. Eight birds were trained on a novel conditional discrimination task with differential rewards, in which background shade (light or dark) determined which of two covered dishes contained a food reward. The reward was small when the background was light, but large when the background was dark. We then presented background shades intermediate between those trained to assess the birds' bias to choose the dish associated with the smaller food reward (a 'pessimistic' judgement) when the discriminative stimulus was ambiguous. Contrary to predictions, changes in the level of cage enrichment had no effect on 'pessimism'. However, changes in the latency to choose and probability of expressing a choice suggested that birds learnt rapidly that trials with ambiguous stimuli were unreinforced. Individual differences in performance of stereotypies did predict 'pessimism'. Specifically, birds that somersaulted were more likely to choose the dish associated with the smaller food reward in the presence of the most ambiguous discriminative stimulus. We propose that somersaulting is part of a wider suite of behavioural traits indicative of a stress response to captive conditions that is symptomatic of a negative affective state

Female Blow Flies As Vertebrate Resource Indicators

Rapid vertebrate diversity evaluation is invaluable for monitoring changing ecosystems worldwide. Wild blow flies naturally recover DNA and chemical signatures from animal carcasses and feces. We demonstrate the power of blow flies as biodiversity monitors through sampling of flies in three environments with varying human influences: Indianapolis, IN and two national parks (the Great Smoky Mountains and Yellowstone). Dissected fly guts underwent vertebrate DNA sequencing (12S and 16S rRNA genes) and fecal metabolite screening. Integrated Nested Laplace Approximation (INLA) was used to determine the most important abiotic factor influencing fly-derived vertebrate richness. In 720 min total sampling time, 28 vertebrate species were identified, with 42% of flies containing vertebrate resources: 23% DNA, 5% feces, and 14% contained both. The species of blow fly used was not important for vertebrate DNA recovery, however the use of female flies versus male flies directly influenced DNA detection. Temperature was statistically relevant across environments in maximizing vertebrate detection (mean = 0.098, sd = 0.048). This method will empower ecologists to test vertebrate community ecology theories previously out of reach due practical challenges associated with traditional sampling