4,499 research outputs found

    Modular symbols and Hecke operators

    Full text link
    We survey techniques to compute the action of the Hecke operators on the cohomology of arithmetic groups. These techniques can be seen as generalizations in different directions of the classical modular symbol algorithm, due to Manin and Ash-Rudolph. Most of the work is contained in papers of the author and the author with Mark McConnell. Some results are unpublished work of Mark McConnell and Robert MacPherson.Comment: 11 pp, 2 figures, uses psfrag.st

    Development of an electronically-scanned pressure module for operation at cryogenic temperatures

    Get PDF
    Pressure and temperature characteristics were measured for a number of multichannel electronically scanned pressure sensors. The tests were made on commercially available units designed to operate in a controlled temperature environment. Measurements of zero shift, sensitivity, and nonlinearity for each transducer were taken over a temperature range from 100 K to 340 K using a computer controlled data acquisition system. The units tested failed to meet accuracy specifications over the complete temperature range, which was expected. However, the sensors showed acceptable and predictable behavior over the temperature range from approximately -40 C (233 K) to 70 C (343 K). It was determined that a combination of local heating and accurate temperature monitoring can result in a device that can be compensated for temperature as well as its other physical properties. The design of a prototype for operation in a cryogenic environment is proposed, and a method for compensation is developed

    Sendero Luminoso and the Peruvian Crisis

    Get PDF

    A Study of a Desensitizing Dentifrice and Cervical Hypersensitivity

    Full text link
    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142179/1/jper0222.pd

    The Health Effects of Increased CVD Medication use Varies by CVD Status of Medicare Beneficiaries

    Get PDF
    Background/Aims: Cardiovascular disease (CVD) is the leading cause of death and disability in the United States. The aim of this study was to assess the effect of increased utilization of CVD medications on MI, stroke, and all-cause mortality among different CVD risk subgroups. Methods: We used 1999-2009 Medicare Current Beneficiary Survey data to identify 26,903 non-institutionalized, fee-for-Service Medicare beneficiaries 65 years or older who were users of angiotensin converting enzyme inhibitor (ACE), angiotensin receptor blocker (ARB), other antihypertensive medications, and statin. These beneficiaries contributed a total of 61,741 person-years. For each study drug, we used logistic regression models to estimate the effect of additional prescription fills on MI, stroke, and all-cause mortality; stratified according to presence of CVD and, in those without CVD, level of CVD risk (high versus low). Results: Additional prescription fills of ACE, ARB, other antihypertensives, or statin did not affect MI occurrence among high CVD risk individuals; while in those with CVD, significant effects of ACE and statin were found: OR per 6 additional fills: 0.76 (95% CI= 0.59, 0.98) and 0.74 (CI= 0.60, 0.92) respectively. Additional drug fills did not affect stroke in either subpopulation except fills of other antihypertensives in the CVD subgroup (OR of 6 additional fills: 0.93 (CI= 0.89, 0.98). In both subgroups, an inverse relationship between increased use of the study drugs and all-cause mortality was generally found although insignificant. For those at lower CVD risk, events were generally too few to allow multivariate analyses. Conclusions: We found inverse relationships between increased use of some CVD medications; and MI, stroke, and mortality (although some were not significant) for some subpopulations but not others. Future research is needed to confirm this to justify the need to eliminate or reduce copays for these drugs for some subgroups that may benefit most from them

    Effects of Increased Utilization of CVD Medications by Medicare Beneficiaries on Spending Vary by CVD Status

    Get PDF
    Background/Aims: To understand the value of our substantial investment in cardiovascular disease (CVD) care, it is important to understand the associations of CVD therapies and spending. The aim of this study was to assess the effect of increased utilization of CVD medications on spending among different CVD risk subgroups. Methods: We used 1999-2009 Medicare Current Beneficiary Survey data to identify 26,903 non-institutionalized, fee-for-Service 65 years or older users of angiotensin converting enzyme inhibitor (ACE), angiotensin receptor blocker (ARBs), other antihypertensives, and statins(61,741person-years). For each drug, we used generalized linear models to estimate the effect of additional prescription fills on spending (i.e. overall, Medicare, out-of-pocket); stratified according to presence of CVD and, in those without CVD, level of CVD risk (high versus low). Results: In the high CVD risk subgroup, each additional prescription fill of ACE, ARB, or statindecreased overall spending (marginal effects: -274(CI=−405,−143),−274 (CI=-405, -143), -139 (CI=-300, 22), and -93(CI=−250,64)respectively)andMedicarespending(marginaleffects:−93 (CI=-250, 64) respectively) and Medicare spending (marginal effects: -273 (CI=-386, -160), -156(CI=−314,3),and−156 (CI=-314, 3), and -160 (CI=-306, -14) respectively). Similar patterns were found in the subgroup with CVD (marginal effects of ACE, ARB, and statins on overall spending: -184(CI=−362,−6),−184 (CI=-362, -6), -184 (CI=-377, 8), and -117(CI=−235,2);andonMedicarespending(−117 (CI=-235, 2); and on Medicare spending (-232 (CI=-362, -103), -186(CI=−363,−9),and−186 (CI=-363, -9), and -229 (CI=-328, -130)). The increased use of these drugs has the opposite effect in the low CVD risk subgroup generally. In contrast, in all 3 subgroups, each additional prescription fill of these drugs generally increased out-of-pocket spending by up to $55. Conclusions: We observed overall cost-savings associated with increased use of CVD medications among both patients with pre-existing CVD and those at high CVD risk. Eliminating or reducing copays for these drugs (i.e. value based insurance design) for such patients may improve their overall health and save money

    Key Issues Generated from the XI International Rangeland Congress 2021: Summary and Way Forward

    Get PDF
    The important issues, knowledge gaps, and evolving research approaches for the global rangelands are summarised in this review of submissions to the Joint XXIV International Grasslands and XI International Rangelands Congress (IGC/IRC). In the big picture, it is concluded that stand-alone studies of livestock production are becoming rare compared to that of the past International Rangelands Congresses (IRC). Rather, added effort is now being directed at understanding the fuller context of social-ecological systems (SESs) on rangelands in a quest to improve the prospects for sustainable resource management as well as the enhancement of human welfare. Although climate change is upon us, there was still a dearth of papers that dealt with broad- scaled climate-adaptation per se; opportunities to improve local drought response were the default topics here with a focus on implementing better drought early warning systems and integrating perspectives among producers and scientists. Invasive species challenges remain as prominent global concerns, and woody encroachment is viewed as a major contributor to rangeland degradation. Treatments to combat rangeland degradation can involve innovative layering methods incorporating grazing management and use of prescribed fire. While there is an important backdrop concerning ecosystem services from rangelands, research in this area is still in its infancy. Analysing trade-offs between production and conservation for services such as carbon sequestration loom large going forward. There were relatively few papers concerning wildlife, tourism, and associated issues; successes and challenges for natural resource conservancies were noted, in particular. These are topics that merit more creative research and development attention in the future. Some contributions highlighted the important issue of landscape conversion from rangelands to cultivation; in conjunction with human population growth, loss of such key resources can be very negative for wildlife and associated values. In terms of pastoralism and related sub-themes, while it was noted that the majority of studies now embrace SESs and integrated, participatory, action- oriented approaches, there is little effort to standardize methodologies. A focus on repeatable methods can help grow sustainability science on rangelands, and this is a challenge for research and outreach education. The volume of studies submitted overall indicated a decided numerical advantage for the Global South over the Global North. Why this is the case remains unclear, however. Disciplinary research traditions in wealthier nations may not yet provide the incentives needed to spur innovative SES work. Finally, policy makers are seen by many investigators as being ignorant of rangeland development issues. It is argued, however, that this view has not changed for 40 years. How to better engage policy makers in comprehensive SES projects is an important future goal. Policy makers themselves can then also become human research subjects in the overall process. Based on our review the future for IRC stakeholders is clear: Continue the expansion of interdisciplinary SES and action-based approaches and increase attention to climate-change adaptation/mitigation, ecosystem services, community-based development, human empowerment, market development, poverty mitigation, and creation of effective policy frameworks
    • …
    corecore