Freeze-dried Products: The Process and the Markets Outline of Key Points for IIFET 2000 Presentation

The presenter from Oregon Freeze-Dry gives an overview of the process and the company

Global Emergency Medicine: A Review of the Literature From 2013

Objectives The Global Emergency Medicine Literature Review ( GEMLR ) conducts an annual search of peer‐reviewed and grey literature relevant to global emergency medicine ( EM ) to identify, review, and disseminate the most important new research in this field to a worldwide audience of academics and clinical practitioners. Methods This year 8,768 articles written in six languages were identified by our search. These articles were distributed among 22 reviewers for initial screening based on their relevance to the field of global EM . An additional two reviewers searched the grey literature. A total of 434 articles were deemed appropriate by at least one reviewer and approved by an editor for formal scoring of overall quality and importance. Results Of the 434 articles that met our predetermined inclusion criteria, 65% were categorized as emergency care in resource‐limited settings, 18% as EM development, and 17% as disaster and humanitarian response. A total of 24 articles received scores of 18 or higher and were selected for formal summary and critique. Interrater reliability for two reviewers using our scoring system was good, with an intraclass correlation coefficient of 0.63 (95% confidence interval = 0.55 to 0.69). Infectious diseases, trauma, and the diagnosis and treatment of diseases common in resource‐limited settings represented the majority of articles selected for final review. Conclusions In 2013, there were more emergency care in resource‐limited settings articles, while the number of disaster and humanitarian response articles decreased, when compared to the 2012 review. However, the distribution of articles selected for full review did not change significantly. As in prior years, the majority of articles focused on infectious diseases, as well as trauma and injury prevention. Resumen Objetivos El grupo Global Emergency Medicine Literature Review (GEMLR) lleva a cabo una búsqueda anual de revisión por pares y de la literatura gris relevante para la Medicina de Urgencias y Emergencias ( MUE ) Global para identificar, revisar y divulgar las investigaciones recientes más importantes en este campo para la audiencia mundial de profesores universitarios y médicos clínicos. Metodología Se identificaron según nuestra búsqueda 8.768 artículos escritos en seis lenguas en 2013. Estos artículos se distribuyeron entre 22 revisores para un despistaje inicial basado en la relevancia para el área de la MUE Global. Dos revisores adicionales buscaron en la literatura gris. Un total de 434 artículos se consideraron apropiados por al menos un revisor y se aprobaron por un editor mediante una puntación formal de calidad e importancia. Resultados De los 434 artículos que cumplieron los criterios de inclusión predeterminados, un 65% se categorizó como atención urgente en escenarios de recursos limitados, un 18% como desarrollo de la MUE y un 17% como grandes catástrofes y respuesta humanitaria. Un total de 24 artículos recibió puntuaciones de 18 o más y se seleccionaron para el resumen formal y la crítica. La concordancia interobservador para los dos revisores usando nuestro sistema de puntuación fue buena con un coeficiente de correlación intraclase de 0,63 (intervalo de confianza 95% = 0,55 a 0,69). Las enfermedades infecciosas, los traumatismos y el diagnostico y tratamiento de las enfermedades comunes en escenarios de recursos limitados representaron la mayoría de los artículos seleccionados para la revisión final. Conclusiones En 2013, hubo más artículos de atención urgente en escenarios de recursos limitados, mientras que el número de artículos de grandes catástrofes y respuesta humanitaria disminuyó respecto a la revisión de 2012. Sin embargo, la distribución de los artículos seleccionados para la revisión total no cambio significativamente. Como en años anteriores, la mayoría de los artículos se centró en enfermedades infecciosas, así como en la prevención de los traumatismos y las lesiones.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108313/1/acem12414.pd

Enhanced Hsp70 Expression Protects against Acute Lung Injury by Modulating Apoptotic Pathways

The Acute respiratory distress syndrome (ARDS) is a highly lethal inflammatory lung disorder. Apoptosis plays a key role in its pathogenesis. We showed that an adenovirus expressing the 70 kDa heat shock protein Hsp70 (AdHSP) protected against sepsis-induced lung injury. In this study we tested the hypothesis that AdHSP attenuates apoptosis in sepsis-induced lung injury

Clinical consequences of road traffic injuries among the elderly in Japan

<p>Abstract</p> <p>Background</p> <p>Road traffic injuries among the elderly have recently become a public health issue; therefore, we investigated the clinical characteristics of such injuries among the elderly in Japan.</p> <p>Methods</p> <p>A retrospective study was performed using data from a medium-sized hospital emergency department. Data were extracted from medical records for one year, and patients were categorized into groups ages 18-64, 65-74 and 75+. Variables included demographic characteristics, injury circumstances, and nature of injury. Univariate and bivariate descriptive statistical analyses were performed, and multivariate logistic regression was used to evaluate injury severity and hospital admission by age groups.</p> <p>Results</p> <p>A total of 1,656 patients were studied. Patients aged 65+ had more chest wall injury, intracranial injury, lower extremity fracture, and intrathoracic injury than patients aged 18-64.</p> <p>Conclusions</p> <p>Injury circumstances and nature of injuries associated with traffic incidents showed different patterns by age groups, particularly among the elderly.</p