Analyzing Domino Effects Occurring on Gasoline Storage Tanks at the Bulk Oil Storage and Transportation (BOST) Depot

Since processed crude oil products are very vulnerable (susceptible) and highly flammable to cause massive catastrophes, such as fire and explosion, which are frequent and can create a chain reaction (Domino effects). This research was carried out at the Bulk Oil Storage and Transportation LTD depot on the Accra plain in Ghana where gasoline and Gasoil are stored. The research was conducted on a flammable gasoline area subjected to a vapor cloud explosion and the hazardous zone. Analyzing domino effects, propagation of a gasoline flammable vapor cloud caused by the explosion, ALOHA (Areal Location of Hazardous Atmospheres) software was used to find out how to apply effective safety measures to prevent future risks at any BOST facilities across the country. After the analysis, it was realized that 5.0 miles to the west-south-west the fuel concentration in the air was 2100 ppm lower than the explosive limit (LEL), and could not be as severe as that at 2.3 miles distance from the source point (12600 ppm LEL) with a greater fuel concentration in the atmosphere. The results made available would be useful in maximizing (improving) safety at the facility, residential area, and as well as minimizing future incidents

Progress on implementation of an accelerated sweetpotato breeding scheme in Ghana.

The sweetpotato support platform for West Africa was established at the CSIR-Crops Research Institute in Kumasi, Ghana in early 2010 with the objective of supporting cultivar development in Ghana and elsewhere in West Africa through the development of adapted less sweet germplasm, and through a participatory approach. The accelerated sweetpotato breeding approach in Ghana uses multi-locational clonal evaluation of seedling families to identify promising families and genotypes, followed by 2 years of additional multi-locational evaluation in target environments. Superior early selections may be used as parents in population improvement in order to speed genetic gain for various attributes. In 2010, roughly 250 genotypes from 34 families, from Ghana, Uganda and Kenya were evaluated at 3 locations, and high yielding, virus resistant genotypes were selected, some at 2 or more locations. In 2011 selected genotypes and introduced clones from diverse sources (330 genotypes) were evaluated in replicated trials at 5 locations covering major production zones and agroecologies. At harvest, farmers were involved in assessment of performance and taste, and selections were evaluated for sugars, minerals and carotenoids using near infrared reflectance spectroscopy. Sixteen genotypes are in advanced trials in 2012.

Multi-locational assessment of some physicochemical attributes and amylase activity of sweetpotato varieties and elite materials in Ghana.

As part of the breeding objectives to select sweetpotato materials with acceptable quality attributes for adaptation and subsequent utilisation in Ghana, the total amylase activity and physicochemical attributes (flesh colour, Beta-carotene, dry matter, starch and sugars) of 13 sweetpotato genotypes across five locations were evaluated. Near Infrared Reflectance Spectrometry (NIRS), was mainly employed in the study. The flesh colour of the materials ranged from white to deep orange while thedry matter content ranged from 20% to 44%. Starch, fructose, glucose and sucrose contents were 46– 74, 0.3 - 5, 2 – 8 and 9 – 22% respectively. Apomuden, a deep orange type, recorded the highesttotal sugar content of 36% and the lowest dry matter and starch content of 20% and 46% respectively. Hi-starch variety had the highest dry matter (45%), starch (74%) and the lowest sugar (11%). Dry matter content correlated positively with starch content whilst orange colour intensity was inversely proportional to dry matter content. The outcome of the study supports the fact that sweet potato contains high extractable amylases. Amylase activity of the materials was fairly stable across locations. Okomkum, Faara, Santom Pona, Kemb, and Cemsa 74-228 recorded the highest activity while Hi-starch, Apomuden, Mohc, and 199062.1 were low. There was no correlation between raw sugars and amylase activity. The potential of individual cultivars for food industry will be discussed in relation to starch content and extractable amylases

How the risk of liver cancer changes after alcohol cessation: A review and meta-analysis of the current literature

<p>Abstract</p> <p>Background</p> <p>It is well established that drinking alcohol raises the risk of liver cancer (hepatocellular carcinoma). However, it has not been sufficiently established as to whether or not drinking cessation subsequently reduces the risk of liver cancer and if it does reduce the risk how long it takes for this heightened risk to fall to that of never drinkers. This question is important for effective policy design and evaluation, to establish causality and for motivational treatments.</p> <p>Methods</p> <p>A systematic review and meta-analysis using the current available evidence and a specific form of Generalised Least Squares is performed to assess how the risk of liver cancer changes with time for former drinkers.</p> <p>Results</p> <p>Four studies are found to have quantified the effect of drinking cessation on the risk of liver cancer. The meta-analysis suggests that the risk of liver cancer does indeed fall after cessation by 6-7% a year, but there remains a large uncertainty around this estimate both statistically and in its interpretation. As an illustration it is estimated that a time period of 23 years is required after drinking cessation, with a correspondingly large 95% confidence interval of 14 to 70 years, for the risk of liver cancer to be equal to that of never drinkers.</p> <p>Conclusion</p> <p>This is a relatively under researched area and this is reflected in the uncertainty of the findings. It is our view that it is not possible to extrapolate the results found here to the general population. Too few studies have addressed this question and of the studies that have, all have significant limitations. The key issue amongst the relevant studies is that it appears that current drinkers, abstainers and former drinkers are not composed of, or effectively adjusted to be, similar populations making inferences about risk changes impossible. This is a very difficult area to study effectively, but it is an important topic. More work is required to reduce both statistical uncertainty and tackle the various study limitations this paper highlights and until this is done, the current result should be considered preliminary.</p

HIV decline in Zimbabwe due to reductions in risky sex? Evidence from a comprehensive epidemiological review.

Published versio

Haemoglobin level at birth is associated with short term outcomes and mortality in preterm infants

Background Blood volume and haemoglobin (Hb) levels are increased by delayed umbilical cord clamping, which has been reported to improve clinical outcomes of preterm infants. The objective was to determine whether Hb level at birth was associated with short term outcomes in preterm infants born at ≤32 weeks gestation. Methods Data were collected retrospectively from electronic records: Standardised Electronic Neonatal Database, Electronic Patient Record, Pathology (WinPath), and Blood Bank Electronic Database. The study was conducted in a tertiary perinatal centre with around 5,500 deliveries and a neonatal unit admission of 750 infants per year. All inborn preterm infants of 23 to 32 weeks gestational age (GA) admitted to the neonatal unit from January 2006 to September 2012 were included. The primary outcomes were intra-ventricular haemorrhage, necrotising entero-colitis, broncho-pulmonary dysplasia, retinopathy of prematurity, and death before discharge. The secondary outcomes were receiving blood transfusion and length of intensive care and neonatal unit days. The association between Hb level (g/dL) at birth and outcomes was analysed by multiple logistic regression adjusting for GA and birth weight (BWt). Results Overall, 920 infants were eligible; 28 were excluded because of missing data and 2 for lethal congenital malformation. The mean (SD) GA was 28.3 (2.7) weeks, BWt was 1,140 (414) g, and Hb level at birth was 15.8 (2.6) g/dL. Hb level at birth was significantly associated with all primary outcomes studied (P <0.001) in univariate analyses. Once GA and BWt were adjusted for, only death before discharge remained statistically significant; the OR of death for infants with Hb level at birth <12 g/dL compared with those with Hb level at birth of ≥18 g/dL was 4.1 (95% CI, 1.4–11.6). Hb level at birth was also significantly associated with blood transfusion received (P <0.01) but not with duration of intensive care or neonatal unit days. Conclusions Low Hb level at birth was significantly associated with mortality and receiving blood transfusion in preterm infants born at ≤32 weeks gestation. Further studies are needed to determine the association between Hb level at birth and long-term neurodevelopmental outcomes

Анализ эффектов домино, возникающих в резервуарах для хранения бензина на складе хранения и транспортировки нефтепродуктов

Since processed crude oil products are very vulnerable (susceptible) and highly flammable to cause massive catastrophes, such as fire and explosion, which are frequent and can create a chain reaction (Domino effects). This research was carried out at the Bulk Oil Storage and Transportation LTD depot on the Accra plain in Ghana where gasoline and Gasoil are stored. The research was conducted on a flammable gasoline area subjected to a vapor cloud explosion and the hazardous zone. Analyzing domino effects, propagation of a gasoline flammable vapor cloud caused by the explosion, ALOHA (Areal Location of Hazardous Atmospheres) software was used to find out how to apply effective safety measures to prevent future risks at any BOST facilities across the country. After the analysis, it was realized that 5.0 miles to the west-south-west the fuel concentration in the air was 2100 ppm lower than the explosive limit (LEL), and could not be as severe as that at 2.3 miles distance from the source point (12600 ppm LEL) with a greater fuel concentration in the atmosphere. The results made available would be useful in maximizing (improving) safety at the facility, residential area, and as well as minimizing future incidents.Переработанные сырые нефтепродукты очень уязвимы (восприимчивы) и легко воспламеняются, что может вызвать массовые катастрофы, такие как пожары и взрывы, они случаются часто и могут вызвать цепную реакцию (эффект домино). Это исследование было проведено на складе компании Bulk Oil Storage and Transportation LTD на равнине Аккра в Гане, где хранятся бензин и дизельное топливо. Исследование проводилось на подвергшемся взрыву парового облака участке с легковоспламеняющимся бензином и на опасной зоне. Для анализа эффекта домино от распространения вызванного взрывом облака горючих паров бензина было использовано программное обеспечение ALOHA (Areal Location of Hazardous Atmospheres), чтобы выяснить, как применять эффективные меры безопасности для предотвращения будущих рисков на любых объектах BOST по всей стране. После анализа было установлено, что в 5,0 мили к западу-юго-западу концентрация топлива в воздухе была на 2100 ppm ниже предела взрываемости (LEL) и не могла быть такой сильной, как на расстоянии 2,3 мили от исходной точки (12600 ppm LEL) с большей концентрацией топлива в атмосфере. Полученные результаты будут полезны для максимизации (повышения) безопасности на объекте, в жилом районе, а также для минимизации будущих инцидентов

The impact of HIV-1 on the malaria parasite biomass in adults in sub-Saharan Africa contributes to the emergence of antimalarial drug resistance

Background. HIV-related immune-suppression increases the risk of malaria (infection, disease and treatment failure) and probably the circulating parasite biomass, favoring the emergence of drug resistance parasites. Methods. The additional malaria parasite biomass related to HIV-1 co-infection in sub-Saharan Africa was estimated by a mathematical model. Parasite biomass was computed as the incidence rate of clinical malaria episodes multiplied by the number of parasites circulating in the peripheral blood of patients at the time symptoms appear. A mathematical model estimated the influence of HIV-1 infection on parasite density in clinical malaria by country and by age group, malaria transmission intensity and urban/rural area. In a multivariate sensitivity analysis, 95% confidence intervals (CIs) were calculated using the Monte Carlo simulation. Results. The model shows that in 2005 HIV-1 increased the overall malaria parasite biomass by 18.0% (95%CI: 11.6-26.9). The largest relative increase (134.9-243.9%) was found in southern Africa where HIV-1 prevalence is the highest and malaria transmission unstable. The largest absolute increase was found in Zambia, Malawi, the Central African Republic and Mozambique, where both malaria and HIV are highly endemic. A univariate sensitivity analysis shows that estimates are sensitive to the magnitude of the impact of HIV-1 infection on the malaria incidence rates and associated parasite densities. Conclusion. The HIV-1 epidemic by increasing the malaria parasite biomass in sub-Saharan Africa may also increase the emergence of antimalarial drug resistance, potentially affecting the health of the whole population in countries endemic for both HIV-1 and malaria

Looking back and moving forward: 50 years of soil and soil fertility management research in sub-Saharan Africa

Article purchased; Published online: 02 Nov 2017Low and declining soil fertility has been recognized for a long time as a major impediment to intensifying agriculture in sub-Saharan Africa (SSA). Consequently, from the inception of international agricultural research, centres operating in SSA have had a research programme focusing on soil and soil fertility management, including the International Institute of Tropical Agriculture (IITA). The scope, content, and approaches of soil and soil fertility management research have changed over the past decades in response to lessons learnt and internal and external drivers and this paper uses IITA as a case study to document and analyse the consequences of strategic decisions taken on technology development, validation, and ultimately uptake by smallholder farmers in SSA. After an initial section describing the external environment within which soil and soil fertility management research is operating, various dimensions of this research area are covered: (i) ‘strategic research’, ‘Research for Development’, partnerships, and balancing acts, (ii) changing role of characterization due to the expansion in geographical scope and shift from soils to farms and livelihoods, (iii) technology development: changes in vision, content, and scale of intervention, (iv) technology validation and delivery to farming communities, and (v) impact and feedback to the technology development and validation process. Each of the above sections follows a chronological approach, covering the last five decades (from the late 1960s till today). The paper ends with a number of lessons learnt which could be considered for future initiatives aiming at developing and delivering improved soil and soil fertility management practices to smallholder farming communities in SSA