Experimental modelling for flexible pavement materials applying advanced laboratory tests to develop mechanistic-empirical design procedure

The fatigue performance of asphalt is addressed in the mechanistic-empirical pavement thickness design procedure used in Australia. The aim of this research program was to investigate the laboratory fatigue performance of a typical asphalt mix used in Western Australia as a structural layer, including the development of new testing protocols, a new fatigue life prediction model, an accelerated testing approach, and master curves that can be input into the M-E design procedures used in Australia

Survey of the diagenesis process and effect these process on reservoir quality of the Kangan formation in South Pars Field

Kangan and Upper Dalan formations are forming reservoir sequence of the South Pars field. Litology of the kangan formation is carbonate and (limestone and dolomite with anhydrite intervals), so digenetic processes were very active in this formation and these processes have changeed the reservoir quality. Importances of the digenetic process are including dissolution, calcite cements, dolomitization, anhydritization, physical and chemical compaction and fracturing

Anti-proliferative effect of the extracts and essential oil of Pimpinella anisum on gastric cancer cells

Introduction: One of the most important fields to find the new drugs for combating cancers is herbal medicine and in this regard, attention to plant components against cancer has been increased nowadays. In the present study, we investigated the cytotoxic effect of alcoholic extracts and essential oil of Pimpinella anisum on viability of gastric cancer cell line (AGS) and angiogenesis of HUVEC cells . Methods: The alcoholic extracts and essential oil were obtained by soxhlet and Clevenger set, respectively. The viability of cells which treated with the extracts and the essential oil were assessed by MTT assay. In vitro tube formation assay was performed to assess the effect of the extracts and essential oil on angiogenesis potential of HUVEC cells. Results: The growth of AGS cells was inhibited by extracts and essential oil of Pimpinella anisum. Furthermore, the extracts and essential oil had inhibitory effects on the angiogenesis in HUVEC cells. The ethanolic extract inhibited cell proliferation of the AGS cells in 30 µg/mL at 48 hours after treatment but it had no significant effect on fibroblast cells. The inhibitory effect of methanolic extract was much better than the ethanolic extract at the same concentrations. The essential oil of the plant had the highest inhibitory effect on cancer cells compared with the alcoholic extracts. Conclusion: Therefore, our results showed that the alcoholic extracts and essential oil of Pimpinella anisum have antiprolifertion properties on gastric cancer cells and could be used as plant-based cures for gastric cancer