2,054 research outputs found
Verification of a localization criterion for several disordered media
We analytically compute a localization criterion in double scattering
approximation for a set of dielectric spheres or perfectly conducting disks
uniformly distributed in a spatial volume which can be either spherical or
layered. For every disordered medium, we numerically investigate a localization
criterion, and examine the influence of the system parameters on the wavelength
localization domains.Comment: 30 pages, LateX, amstex, revtex styles, 20 figure
Quick Test for Quality Deterioration in Processed Foods
A quick test for quality deterioration of milk powder, refined oil and atta, based on the indicator test solution was studied. The indicator test solution comprising NaOH and bromotIlytnol blue indicator remains stable for 6 mont1ls itl glass bottles. Depending on the acidity of the Sample, the colour changed from blue to light blue to green to yellow. The concentration of the indicator test solution is optimised for each product, viz., 4 ml for milk powder and refined oil and 2 ml for atta, to which 1 ml aqueous sample or oil is added which gives the colour change. The appearance of green colour is considered tIle cutoff point for inferior quality alld is based on the limits specified by the Bureau of Indian Standards for these products. The test has proved its efficacy in quality checking during storage of milk powder and deep fat frying of products in refined oils
Comparative evaluation of different reference evapotranspiration models
The study was carried out to select best alternative method for the estimation of reference evapotranspi-ration (ET0). Accurate estimation of potential evapotranspiration is a necessary step in water resource management. Recently, the FAO-56 version of Penman-Monteith equation has been established as a standard for calculating ref-erence evapotranspiration (ET0) which requires measurement of a number of meteorological parameters namely, air temperature, relative humidity, solar radiation, and wind speed which may not be available in most of the meteoro-logical stations. Still there are different approaches (requiring less data) which estimate ET0 closely to Penman- Monteith (P-M) method for different climatological conditions. The present study is based on analysis of long term of 13 years (2000 to 2012) climatic data to calculate monthly reference evapotranspiration for Capsicum production (September–March) and also to compare the performance of evapotranspiration equations for Jhalawar district of Rajasthan with the standard FAO-56 Penman-Monteith method on the basis of the least root mean square error (RMSE) analysis. Hargreaves method and Pan evaporation (E-Pan) method overestimated the values of ETo when compared with FAO-56 Penman-Monteith method. On the basis of lowest value of RMSE, Pan evaporation method is found best alternative method to FAO-56 Penman-Monteith method in the study area
Cross-Sender Bit-Mixing Coding
Scheduling to avoid packet collisions is a long-standing challenge in
networking, and has become even trickier in wireless networks with multiple
senders and multiple receivers. In fact, researchers have proved that even {\em
perfect} scheduling can only achieve . Here
is the number of nodes in the network, and is the {\em medium
utilization rate}. Ideally, one would hope to achieve ,
while avoiding all the complexities in scheduling. To this end, this paper
proposes {\em cross-sender bit-mixing coding} ({\em BMC}), which does not rely
on scheduling. Instead, users transmit simultaneously on suitably-chosen slots,
and the amount of overlap in different user's slots is controlled via coding.
We prove that in all possible network topologies, using BMC enables us to
achieve . We also prove that the space and time
complexities of BMC encoding/decoding are all low-order polynomials.Comment: Published in the International Conference on Information Processing
in Sensor Networks (IPSN), 201
A Static Optimality Transformation with Applications to Planar Point Location
Over the last decade, there have been several data structures that, given a
planar subdivision and a probability distribution over the plane, provide a way
for answering point location queries that is fine-tuned for the distribution.
All these methods suffer from the requirement that the query distribution must
be known in advance.
We present a new data structure for point location queries in planar
triangulations. Our structure is asymptotically as fast as the optimal
structures, but it requires no prior information about the queries. This is a
2D analogue of the jump from Knuth's optimum binary search trees (discovered in
1971) to the splay trees of Sleator and Tarjan in 1985. While the former need
to know the query distribution, the latter are statically optimal. This means
that we can adapt to the query sequence and achieve the same asymptotic
performance as an optimum static structure, without needing any additional
information.Comment: 13 pages, 1 figure, a preliminary version appeared at SoCG 201
AN UPDATED REVIEW ON THE APPLICATION OF DENDRIMERS AS SUCCESSFUL NANOCARRIERS FOR BRAIN DELIVERY OF THERAPEUTIC MOIETIES
It’s been nearly 100 y of effort to study the organization and role of the blood brain-barrier and still, we strive to find better techniques to overcome this barrier to deliver the drugs to the brain effectively with reduced systemic side effects. The advances in nanotechnology have given newer horizons in achieving this goal since the nano-scaled systems can modify an existing drug to have a high degree of sensitivity to the physiological conditions and specificity to reach the target organ. Among the various nanocarriers, dendrimers owing to their unique physical and chemical characteristics, represent a potential therapeutic tool in biomedical and pharmaceutical science. Dendrimers, an established polymeric nanocarrier system of the time, can deliver both drugs and genetic material and are being extensively studied to target the brain. The surface modification of dendrimers can reduce their innate toxicity problems and increase the therapeutic efficacy of brain disorders. This review article is an attempt to update on the potential of dendrimers explored in the past five years as a drug delivery avenue that can be considered as a promising solution in the management of a wide range of disorders affecting the central nervous system, including neoplastic, degenerative, and ischemic conditions. The following search criteria were used to expand the review article with the keywords dendrimers, novel drug delivery, nanoparticles, site-specific drug delivery etc
Locating Depots for Capacitated Vehicle Routing
We study a location-routing problem in the context of capacitated vehicle
routing. The input is a set of demand locations in a metric space and a fleet
of k vehicles each of capacity Q. The objective is to locate k depots, one for
each vehicle, and compute routes for the vehicles so that all demands are
satisfied and the total cost is minimized. Our main result is a constant-factor
approximation algorithm for this problem. To achieve this result, we reduce to
the k-median-forest problem, which generalizes both k-median and minimum
spanning tree, and which might be of independent interest. We give a
(3+c)-approximation algorithm for k-median-forest, which leads to a
(12+c)-approximation algorithm for the above location-routing problem, for any
constant c>0. The algorithm for k-median-forest is just t-swap local search,
and we prove that it has locality gap 3+2/t; this generalizes the corresponding
result known for k-median. Finally we consider the "non-uniform"
k-median-forest problem which has different cost functions for the MST and
k-median parts. We show that the locality gap for this problem is unbounded
even under multi-swaps, which contrasts with the uniform case. Nevertheless, we
obtain a constant-factor approximation algorithm, using an LP based approach.Comment: 12 pages, 1 figur
SUPPORTIVE THERAPY: AN OPTION TO ENHANCE HOST IMMUNITY AGAINST COVID-19
The threat posed by COVID 19 outbreak, which is considered to be a global pandemic, is immeasurably affecting all the communities worldwide. COVID-19 is a zoonotic disease, which can affect birds, humans and, other animals. The emergence of this pandemic has been creating a tragic situation worldwide by affecting more people through human-human transmission. The burden (both healthwise and economic) placed by the disease is so huge that any measures to improve the current situation, to fasten up the recovery of already affected patients and, to reduce the risk of death and health deterioration should be considered. Vaccination, being the hope in the scenario, helps in preventing the condition to an extent, but in the absence of availability of a proper drug regimen to fight off COVID 19, the requirement of the need to find a system to control the severity of the infection is a necessity Nutritional supplementation helps in boosting up the immune system especially, vitamins like vitamin C, Vitamin D, Zinc, Omega 3 fatty acids, etc. They also exhibit established immunomodulatory, antiviral as well as anti-inflammatory effects. Pieces of evidence have also highlighted the importance of supportive therapy using nutrient supplements in covid patients as it helps in prominent decreasing of SARS CoV2 load of the virus and also significantly reduces the hospitalization period. Hence the nutritional levels of each of the infected person must be assessed before initiating the anti-viral therapy. The search criteria used were PubMed, Medscape, google scholar, etc. The keywords used to search were COVID 19 Supportive therapy, Vitamin D, Vitamin C, Nutrient supplementation, Host immunity, etc. The range of years is between 1978 and 2021
STATE-OF-THE-ART NANOTECHNOLOGY BASED DRUG DELIVERY STRATEGIES TO COMBAT COVID-19
The emerging Coronavirus Disease-19 (COVID-19) pandemic has had a global impact on all important aspects of our society. As it is known, SARS-Cov-2 can withstand up to 72 h in adverse environmental conditions, which can aid its rapid spread. Woefully, an efficacious and approbated vaccine for the SARS-CoV-2 virus remains unavailable, which makes the problem more frightening and presently more complicated bestowing forlorn medical care. Nevertheless, global clinical research is studying several over-the-counter (OTC) drugs approved for other indications to confront coronavirus. Over the past decade, therapeutic nanoparticles have been regarded as a felicitous tool for the efficient and persnickety delivery of therapeutic groups (i.e., drugs, vaccines, siRNAs, and peptides) to the site of infection. They can adequately convey the drug encapsulated nanoparticle to a designated locus without instigating unsought effects. Besides, they acquiesce the use of non-invasive imaging methods to monitor the surface of the infection and the response to treatment. The formulated nanoparticle is apposite for intranasal drug delivery which is a meritorious method to deliver therapeutic moiety for viral diseases affecting the lungs. Applying nanoparticles via intranasal route surmounted several demerits of mucosal administration like circumventing enzymatic degradation of the therapeutic moiety, upgrading and prolonging the action of the drug, etc., and can thus corroborate as an exceptional strategy to encounter respiratory viruses like coronavirus. In this article, we illuminate the promising role of nanoparticles as effective carriers of therapeutic or immunomodulatory agents to help combat COVID-19.
The search criteria used were Pubmed, Medscape, Google scholar, etc and the keywords are coronavirus, nanoformulations, nanoparticles, drug delivery, intranasal delivery, etc. The articles range from 2012 to 2020
Analytical Study on Flexural Behaviour of Glued Laminated Timber
ABSTRACT: This study determines analytically the flexural properties of glued laminated timber beam (glulam) with different thickness of lamina and jointed lamina; it was compared to solid beam. This research used Rubber wood (Hevea brasiliensis). Glulam beam was divided into three groups based on the thickness of lamina, 20 mm, 15 mm and 10 mm respectively. Solid beam was also modelled besides glulam beam. Jointed wood with finger outside maximum moment zone in the bottom lamina was also modelled. Solid wood and laminated wood of rubber wood species was modelled and analysed in ANSYS 14.5.Then modelling of finger joint was done in Computer Aided Three-dimensional Interactive Application (CATIA) and analysed in ANSYS. The result was compared with the available experimental result. The results obtained show that the comparison of flexural properties between solid wood and horizontally glulam wood have no significant difference. Lamina thickness does not make any statistically significant difference in the flexural properties
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