15 research outputs found
Deep Learning Activation Layer-Based Wall Quality Recognition Using Conv2D ResNet Exponential Transfer Learning Model
Crack detection is essential for observing structural health and guaranteeing structural safety. The manual crack and other damage detection process is time-consuming and subject to surveyors’ biased judgments. The proposed Conv2D ResNet Exponential model for wall quality detection was trained with 5000 wall images, including various imperfections such as cracks, holes, efflorescence, damp patches, and spalls. The model was trained with initial weights to form the trained layers of the base model and was integrated with Xception, VGG19, DenseNet, and ResNet convolutional neural network (CNN) models to retrieve the general high-level features. A transfer deep-learning-based approach was implemented to create a custom layer of CNN models. The base model was combined with custom layers to estimate wall quality. Xception, VGG19, DenseNet, and ResNet models were fitted with different activation layers such as softplus, softsign, tanh, selu, elu, and exponential, along with transfer learning. The performance of Conv2D was evaluated using model loss, precision, accuracy, recall, and F-score measures. The model was validated by comparing the performances of Xception, VGG19, DenseNet, ResNet, and Conv2D ResNet Exponential. The experimental results show that the Conv2D ResNet model with an exponential activation layer outperforms it with an F-score value of 0.9978 and can potentially be a viable substitute for classifying various wall defects
The Renin-Angiotensin and Renal Dopaminergic Systems Interact in Normotensive Humans.
The renin-angiotensin-aldosterone (RAAS) and renal dopaminergic systems interact to maintain sodium balance. High NaCl intake increases renal synthesis of dopamine and dopaminergic receptor activity, decreasing epithelial sodium transport, whereas sodium deficit activates the RAAS, increasing epithelial sodium transport. We tested the hypothesis that attenuation of the natriuretic effect of dopamine D(1)-like receptors during salt restriction results in part from increased RAAS activity in seven salt-resistant normotensive adults using a double-blind placebo-controlled balanced crossover design. All subjects attained sodium balance on low (50 mmol Na(+)/day) and high (300 mmol Na(+)/day) NaCl diets, administered 4 weeks apart. Sodium, potassium, lithium, para-aminohippurate, and creatinine clearances were measured before, during, and after a 3-hour infusion of fenoldopam, a D(1)-like receptor agonist, with and without pretreatment with enalapril, an angiotensin converting enzyme inhibitor. On the high NaCl diet, fenoldopam-induced natriuresis was associated with the inhibition of renal proximal and distal tubule sodium transport. On the low NaCl diet, fenoldopam decreased renal distal tubule sodium transport but did not cause natriuresis. The addition of enalapril to fenoldopam restored the natriuretic effect of fenoldopam and its inhibitory effect on proximal tubule sodium transport. Thus, on a high NaCl diet fenoldopam causes natriuresis by inhibiting renal proximal and distal tubule transport, but on a low NaCl diet the increased RAAS activity prevents the D(1)-like receptor from inhibiting renal proximal tubule sodium transport, neutralizing the natriuretic effect of fenoldopam. These results demonstrate an interaction between the renin-angiotensin and renal dopaminergic systems in humans and highlight the influence of dietary NaCl on these interactions
Pulmonary Complications of Pediatric Hematopoietic Cell Transplantation. A National Institutes of Health Workshop Summary
Approximately 2,500 pediatric hematopoietic cell transplants (HCTs), most of which are allogeneic, are performed annually in the United States for life-threatening malignant and nonmalignant conditions. Although HCT is undertaken with curative intent, post-HCT complications limit successful outcomes, with pulmonary dysfunction representing the leading cause of nonrelapse mortality. To better understand, predict, prevent, and/or treat pulmonary complications after HCT, a multidisciplinary group of 33 experts met in a 2-day National Institutes of Health Workshop to identify knowledge gaps and research strategies most likely to improve outcomes. This summary of Workshop deliberations outlines the consensus focus areas for future research
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Not AvailableWith continually increasing demand for food accompanied by the constraints of climate
change and the availability and quality of soil and water, the world’s farmers are
challenged to produce more food per hectare with less water, and with fewer
agrochemical inputs if possible. The ideas and methods of the system of rice
intensification which is improving irrigated rice production are now being extended/
adapted to many other crops: wheat, maize, finger millet, sugarcane, tef, mustard,
legumes, vegetables, and even spices. Promoting better root growth and enhancing
the soil’s fertility with organic materials are being found effective means for raising
the yields of many crop plants with less water, less fertilizer, reduced seeds, fewer
agrochemicals, and greater climate resilience. In this article, we review what is
becoming known about various farmer-centred innovations for agroecological crop
management that can contribute to agricultural sustainability. These changes
represent the emerging system of crop intensification, which is being increasingly
applied in Asian, African, and Latin American countries. More research will be needed
to verify the efficacy and impact of these innovations and to clarify their conditions
and limits. But as no negative effects for human or environmental health have been
identified, making these agronomic options more widely known should prompt more
investigation and, to the extent justified by results, utilization of these methodologiesNot Availabl