869 research outputs found

    The Conal representation of Quantum States and Non Trace-Preserving Quantum Operations

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    We represent generalized density matrices of a dd-complex dimensional quantum system as a subcone of a real pointed cone of revolution in Rd2\mathbb{R}^{d^2}, or indeed a Minkowskian cone in E1,d21\mathbb{E}^{1,d^2-1}. Generalized pure states correspond to certain future-directed light-like vectors of E1,d21\mathbb{E}^{1,d^2-1}. This extension of the Generalized Bloch Sphere enables us to cater for non-trace-preserving quantum operations, and in particluar to view the per-outcome effects of generalized measurements. We show that these consist of the product of an orthogonal transform about the axis of the cone of revolution and a positive real linear transform. We give detailed formulae for the one qubit case and express the post-measurement states in terms of the initial state vectors and measurement vectors. We apply these results in order to find the information gain versus disturbance tradeoff in the case of two equiprobable pure states. Thus we recover Fuchs and Peres' formula in an elegant manner.Comment: 11 pages, revtex, v3: some typos correcte

    A Simple n-Dimensional Intrinsically Universal Quantum Cellular Automaton

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    We describe a simple n-dimensional quantum cellular automaton (QCA) capable of simulating all others, in that the initial configuration and the forward evolution of any n-dimensional QCA can be encoded within the initial configuration of the intrinsically universal QCA. Several steps of the intrinsically universal QCA then correspond to one step of the simulated QCA. The simulation preserves the topology in the sense that each cell of the simulated QCA is encoded as a group of adjacent cells in the universal QCA.Comment: 13 pages, 7 figures. In Proceedings of the 4th International Conference on Language and Automata Theory and Applications (LATA 2010), Lecture Notes in Computer Science (LNCS). Journal version: arXiv:0907.382

    Central Review of Amyloid-Related Imaging Abnormalities in Two Phase III Clinical Trials of Bapineuzumab in Mild-To-Moderate Alzheimer's Disease Patients

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    BACKGROUND: Amyloid-related imaging abnormalities (ARIA) consist of ARIA-E (with effusion or edema) and ARIA-H (hemosiderin deposits [HDs]). OBJECTIVES: To address accurate ascertainment of ARIA identification, a final magnetic resonance imaging (MRI) reading was performed on patients with mild-to-moderate Alzheimer’s disease randomized to bapineuzumab IV or placebo during two Phase III trials (APOE ɛ4 allele carriers or noncarriers). METHODS: Final MRI central review consisted of a systematic sequential locked, adjudicated read in 1,331 APOE ɛ4 noncarriers and 1,121 carriers by independent neuroradiologists. Assessment of ARIA-E, ARIA-H, intracerebral hemorrhages, and age-related white matter changes is described. RESULTS: In the Final Read, treatment-emergent ARIA-E were identified in 242 patients including 76 additional cases not noted previously in real time. Overall, incidence proportion of ARIA-E was higher in carriers (active 21.2%; placebo 1.1%) than in noncarriers (pooled active 11.3%; placebo 0.6%), and was more often identified in homozygote APOE ɛ4 carriers than heterozygotes (34.5% versus 16.9%). Incidence rate of ARIA-E increased with increased dose in noncarriers. Frequency of ARIA-E first episodes was highest after the first and second bapineuzumab infusion and declined after repeated infusions. Incidence of total HDs <10 mm (cerebral microhemorrhages) was higher in active groups versus placebo. CONCLUSION: ARIA was detected more often on MRI scans when every scan was reviewed by trained neuroradiologists and results adjudicated. There was increased incidence of ARIA-E in bapineuzumab-treated carriers who had a microhemorrhage at baseline. ARIA-E was a risk factor for incident ARIA-H and late onset ARIA-E was milder radiologically. Age-related white matter changes did not progress during the study

    The substitution of a tetrahedron for the Einthoven triangle

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    In an experiment on a cadaver, a potential difference was rhythmically impressed upon two small electrodes thrust into the heart or its immediate neighborhood.The resulting differences in potential between a central terminal and four electrodes connected to it through equal resistances were recorded with the string galvanometer. The four electrodes were on the two arms, the left leg, and the left interscapular region.By assuming that the electrical field generated in the trunk was equivalent to that of a centric doublet in a homogeneous spherical conductor and that the four electrodes were at the apices of a tetrahedron inscribed in this sphere, the experimental and the theoretical amplitudes of the deflections in the four leads could be compared. In general, it may be said that, with one exception, the deflections in the limb leads had the relative magnitudes expected. The deflections in the lead from the back were much smaller than anticipated. The last result is attributed to circumstances peculiar to the single experiment performed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32563/1/0000689.pd

    Geographical interdependence, international trade and economic dynamics: the Chinese and German solar energy industries

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    The trajectories of the German and Chinese photovoltaic industries differ significantly yet are strongly interdependent. Germany has seen a rapid growth in market demand and a strong increase in production, especially in the less developed eastern half of the country. Chinese growth has been export driven. These contrasting trajectories reflect the roles of market creation, investment and credit and the drivers of innovation and competitiveness. Consequent differences in competiveness have generated major trade disputes
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