Identifying new X-ray binary candidates in M31 using random forest classification

Identifying X-ray binary (XRB) candidates in nearby galaxies requires distinguishing them from possible contaminants including foreground stars and background active galactic nuclei. This work investigates the use of supervised machine learning algorithms to identify highprobability XRB candidates. Using a catalogue of 943 Chandra X-ray sources in the Andromeda galaxy, we trained and tested several classification algorithms using the X-ray properties of 163 sources with previously known types. Amongst the algorithms tested, we find that random forest classifiers give the best performance and work better in a binary classification (XRB/non-XRB) context compared to the use of multiple classes. Evaluating our method by comparingwith classifications from visible-light and hardX-ray observations as part of the Panchromatic Hubble Andromeda Treasury, we find compatibility at the 90 per cent level, although we caution that the number of source in common is rather small. The estimated probability that an object is an XRB agrees well between the random forest binary and multiclass approaches and we find that the classifications with the highest confidence are in the XRB class. Themost discriminating X-ray bands for classification are the 1.7-2.8, 0.5-1.0, 2.0-4.0, and 2.0-7.0 keV photon flux ratios. Of the 780 unclassified sources in the Andromeda catalogue, we identify 16 new high-probability XRB candidates and tabulate their properties for follow-up

A prospective analysis of the injury incidence of young male professional football players on artificial turf

Background: The effects of synthetic surfaces on the risk of injuries is still debated in literature and the majority of published data seems to be contradictory. For such reasons the understanding of injury incidence on such surfaces, especially in youth sport, is fundamental for injury prevention. Objectives: The aim of this study was to prospectively report the epidemiology of injuries in young football players, playing on artificial turfs, during a one sports season. Patients and Methods: 80 young male football players (age 16.1 ± 3.7 years; height 174 ± 6.6 cm; weight 64.2 ± 6.3 kg) were enrolled in a prospective cohort study. The participants were then divided in two groups; the first included players age ranging from 17 to 19 (OP) whereas the second included players age ranging from 13 to 16 (YP). Injury incidence was recorded prospectively, according to the consensus statement for soccer. Results: A total of 107 injuries (35 from the OP and 72 from the YP) were recorded during an exposure time of 83.760 hours (incidence 1.28/1000 per player hours); 22 during matches (incidence 2.84/1000 per player hours, 20.5%) and 85 during training (incidence 1.15/1000 per player hours, 79.5%). Thigh and groin were the most common injury locations (33.6% and 21.5%, respectively) while muscle injuries such as contractures and strains were the most common injury typologies (68.23%). No statistical differences between groups were displayed, except for the rate of severe injuries during matches, with the OP displaying slightly higher rates compared to the YP. Severe injuries accounted for 10.28% of the total injuries reported. The average time lost due to injuries was 14 days. Re-injuries accounted for 4.67% of all injuries sustained during the season. Conclusions: In professional youth soccer injury rates are reasonably low. Muscle injuries are the most common type of injuries while groin and thigh the most common locations. Artificial turf pitches don’t seem to contribute to injury incidence in young football players

Distances to Galactic X-ray binaries with Gaia DR2

Precise and accurate measurements of distances to Galactic X-ray binaries (XRBs) reduce uncertainties in the determination of XRB physical parameters. We have cross-matched the XRB catalogues of Liu, van Paradijs & van den Heuvel to the results of Gaia Data Release 2. We identify 86 XRBs with a Gaia candidate counterpart, of which 32 are low-mass X-ray binaries (LMXBs) and 54 are high-mass X-ray binaries (HMXBs). Distances to Gaia candidate counterparts are, on average, consistent with those measured by Hipparcos and radio parallaxes. When compared to distances measured by Gaia candidate counterparts, distances measured using Type I X-ray bursts are systematically larger, suggesting that these bursts reach only 50 per cent of the Eddington limit. However, these results are strongly dependent on the prior assumptions used for estimating distance from the Gaia parallax measurements. Comparing positions of Gaia candidate counterparts for XRBs in our sample to positions of spiral arms in the Milky Way, we find that HMXBs exhibit mild preference for being closer to spiral arms; LMXBs exhibit mild preference for being closer to interarm regions. LMXBs do not exhibit any preference for leading or trailing their closest spiral arm. HMXBs exhibit a mild preference for trailing their closest spiral arm. The lack of a strong correlation between HMXBs and spiral arms may be explained by star formation occurring closer to the mid-point of the arms, or a time delay between star formation and HMXB formation manifesting as a spatial separation between HMXBs and the spiral arm where they formed

Large-Scale Structure in Brane-Induced Gravity II. Numerical Simulations

We use N-body simulations to study the nonlinear structure formation in brane-induced gravity, developing a new method that requires alternate use of Fast Fourier Transforms and relaxation. This enables us to compute the nonlinear matter power spectrum and bispectrum, the halo mass function, and the halo bias. From the simulation results, we confirm the expectations based on analytic arguments that the Vainshtein mechanism does operate as anticipated, with the density power spectrum approaching that of standard gravity within a modified background evolution in the nonlinear regime. The transition is very broad and there is no well defined Vainshtein scale, but roughly this corresponds to k_*~ 2 at redshift z=1 and k_*~ 1 at z=0. We checked that while extrinsic curvature fluctuations go nonlinear, and the dynamics of the brane-bending mode C receives important nonlinear corrections, this mode does get suppressed compared to density perturbations, effectively decoupling from the standard gravity sector. At the same time, there is no violation of the weak field limit for metric perturbations associated with C. We find good agreement between our measurements and the predictions for the nonlinear power spectrum presented in paper I, that rely on a renormalization of the linear spectrum due to nonlinearities in the modified gravity sector. A similar prediction for the mass function shows the right trends. Our simulations also confirm the induced change in the bispectrum configuration dependence predicted in paper I.Comment: 19 pages, 13 figures. v2: corrected typos, added more simulations, better test of predictions in large mass regime. v3: minor changes, published versio

Multiwavelength survey of X-ray sources in the sculptor dwarf spheroidal galaxy

We present an unprecedented, deep study of the primordial low-mass X-ray binary population in an isolated, lower metallicity environment. We perform follow-up observations of previously identified X-ray binary candidates in the Sculptor Dwarf Galaxy by combining a second Chandra observation with Spitzer and Gemini photometry, as well as Gemini spectroscopy of selected targets. Of the original nine bright X-ray sources identified, we are able to classify all but one as quasars, active galactic nuclei, or background galaxies. We further discover four new X-ray sources in the second-epoch Chandra observation. Three of these new sources are background sources and one is a foreground flaring star. We have found that Sculptor is effectively devoid of X-ray sources above a few 1034 erg s−1. If Sculptor is able to retain primordial binaries at a similar rate to globular clusters, this implies that bright X-ray binaries observed in globular clusters in the present epoch are all formed dynamically

Pharmacy study of natural health product adverse reactions (SONAR): a cross-sectional study using active surveillance in community pharmacies to detect adverse events associated with natural health products and assess causality

OBJECTIVES: To investigate the rates and causality of adverse event(s) (AE) associated with natural health product (NHP) use, prescription drug use and concurrent NHP-drug use through active surveillance in community pharmacies. DESIGN: Cross-sectional study of screened patients. SETTING: 10 community pharmacies across Alberta and British Columbia, Canada from 14 January to 30 July 2011. PARTICIPANTS: The participating pharmacy staff screened consecutive patients, or agents of patients, who were dropping or picking up prescription medications.PRIMARY OUTCOME MEASURES: Patients were screened to determine the proportions of them using prescription drugs and/or NHPs, as well as their respective AE rates. All AEs reported by the screened patients who took a NHP, consented to, and were available for, a detailed telephone interview (14%) were adjudicated fully to assess for causality.RESULTS: Over a total of 105 pharmacy weeks and 1118 patients screened, 410 patients reported taking prescription drugs only (36.7%; 95% CI 33.9% to 39.5%), 37 reported taking NHPs only (3.3%; 95% CI 2.4% to 4.5%) and 657 reported taking prescription drugs and NHPs concurrently (58.8%; 95% CI 55.9% to 61.6%). In total, 54 patients reported an AE, representing 1.2% (95% CI 0.51% to 2.9%), 2.7% (95% CI 0.4% to 16.9%) and 7.3% (95% CI 5.6% to 9.6%) of each population, respectively. Compared with patients who reported using prescription drugs, the patients who reported using prescription drugs and NHPs concurrently were 6.4 times more likely to experience an AE (OR; 95% CI 2.52 to 16.17; p<0.001). Combined with data from Ontario, Canada, a national proportion was calculated, which found that 45.4% (95% CI 43.8% to 47.0%) of Canadians who visit community pharmacies take NHPs and prescription drugs concurrently, and of those, 7.4% (95% CI 6.3% to 8.8%) report an AE.CONCLUSIONS: A substantial proportion of community pharmacy patients use prescription drugs and NHPs concurrently; these patients are at a greater risk of experiencing an AE. Active surveillance provides a means of detecting such AEs and collecting high-quality data on which causality assessment can be based

Comparative chromosome painting discloses homologous Segments in distantly related mammals

Comparative chromosome painting, termed ZOO-FISH, using DNA libraries from flow sorted human chromosomes 1,16,17 and X, and mouse chromosome 11 discloses the presence of syntenic groups in distantly related mammalian Orders ranging from primates (Homo sapiens), rodents (Mus musculus), even-toed ungulates (Muntiacus muntjak vaginalis and Muntiacus reevesi) and whales (Balaenoptera physalus). These mammalian Orders have evolved separately for 55-80 million years (Myr). We conclude that ZOO-FISH can be used to generate comparative chromosome maps of a large number of mammalian species

Transforming bonds: ritualising post-mortem relationships in the Netherlands

People continue relationships with their dead in a variety of ways. Since the 1990s, the idea of ‘continuing bonds’ has provided a framework for exploring and understanding post-mortem relationships. However, the dynamics of the bonds between the living and the dead have received little attention. By looking at the intersection of things, practices and spaces, this paper demonstrates that expressions of continuing bonds do not always point to continuity, and indeed can signify discontinuity. It explores the ‘transforming bonds’ between the recently bereaved and their deceased in the Netherlands, illustrating how post-mortem relationships change and how such changes affect the social location of the deceased and the bereaved. By attending to the ritual dynamics of separation, transition and integration, two aspects of the social and material relationships between the living and the dead are highlighted. First, attention is given to the ways wherein the bereaved relocate their deceased through material objects within and outside of their homes, enabling them to renegotiate the absence–presence of the deceased. Second, the paper illustrates that personalised incorporation practices are inevitably linked to negotiations and contestations in the social sphere, and the norms and values of the social environment

Postharvest insect resistance in maize

One of the main challenges for the 21st century is ensuring global food security. Today, maize is the largest staple crop produced worldwide. Postharvest primary insect pests, especially the maize weevil (Sitophilus zeamais) and the large grain borer (Prostephanus truncatus) cause food-grain losses during storage up to 40% of total production, mainly in developing countries. Alternatives for pest management have been explored, including the implementation of hermetic storage structures and the application of chemical insecticides. Nevertheless, in low-income regions, both strategies are rarely accessible to smallholders. Modern breeding programs have endeavored to develop insect-resistant varieties, which diminish postharvest pest losses. In this review, we report the current status and advances in maize kernel-pest interactions, the bases and mechanisms of kernel resistance and their biotechnological perspectives. We demonstrate that the comprehension of resistance mechanisms has been fundamental for the development of new productive and resistant varieties, representing a sustainable alternative for developing countries. Finally, we analyse the biotechnological perspectives of natural kernel resistance in global food security