Validation of a roll decay test of an offshore installation vessel using openfoam

In this work, the offshore heavy lift DP2 jack-up vessel Innovation from the DEME group is studied using the Computational Fluid Dynamics (CFD) toolbox OpenFOAM. The two-phase Navier-Stokes fluid solver is coupled with a motion solver using a partitioned fluid-structure interaction algorithm. Firstly, two dimensional numerical simulations of a cross-section of the hull are performed using two different mesh motion techniques: a mesh morphing method and an overset mesh method. Subsequently, the addition of a bilge keel pair on the hull is studied numerically by performing a two dimensional roll decay simulation. Finally, a three dimensional simulation is performed for a roll decay test and validated by using experimental data measured in the MARIN seakeeping and manoeuvring basin. As a first result, the coupled CFD–motion solver proofs to be a promising toolbox for the study of fluid-structure interaction problems of realistic marine structures such as an offshore installation vessel

Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure

Upon myocardial damage, the release of cardiac proteins induces a strong antibody-mediated immune response, which can lead to adverse cardiac remodeling and eventually heart failure (HF). Stem cell therapy using mesenchymal stromal cells (MSCs) or cardiomyocyte progenitor cells (CPCs) previously showed beneficial effects on cardiac function despite low engraftment in the heart. Paracrine mediators are likely of great importance, where, for example, MSC-derived extracellular vesicles (EVs) also show immunosuppressive properties in vitro. However, the limited capacity of MSCs to differentiate into cardiac cells and the sufficient scaling of MSC-derived EVs remain a challenge to clinical translation. Therefore, we investigated the immunosuppressive actions of endogenous CPCs and CPC-derived EVs on antibody production in vitro, using both healthy controls and end-stage HF patients. Both MSCs and CPCs strongly inhibit lymphocyte proliferation and antibody production in vitro. Furthermore, CPC-derived EVs significantly lowered the levels of IgG1, IgG4, and IgM, especially when administered for longer duration. In line with previous findings, plasma cells of end-stage HF patients showed high production of IgG3, which can be inhibited by MSCs in vitro. MSCs and CPCs inhibit in vitro antibody production of both healthy and end stage HF-derived immune cells. CPC-derived paracrine factors, such as EVs, show similar effects, but do not provide the complete immunosuppressive capacity of CPCs. The strongest immunosuppressive effects were observed using MSCs, suggesting that MSCs might be the best candidates for therapeutic targeting of B-cell responses in HF

Temperature and surgical wound heat loss during orthopedic surgery: computer simulations and measurements

No Abstrac

Corrosion challenges towards a sustainable society

A global transition towards more sustainable, affordable and reliable energy systems is being stimulated by the Paris Agreement and the United Nation's 2030 Agenda for Sustainable Development. This poses a challenge for the corrosion industry, as building climate-resilient energy systems and infrastructures brings with it a long-term direction, so as a result the long-term behaviour of structural materials (mainly metals and alloys) becomes a major prospect. With this in mind "Corrosion Challenges Towards a Sustainable Society" presents a series of cases showing the importance of corrosion protection of metals and alloys in the development of energy production to further understand the science of corrosion, and bring the need for research and the consequences of corrosion into public and political focus. This includes emphasis on the limitation of greenhouse gas emissions, on the lifetime of infrastructures, implants, cultural heritage artefacts, and a variety of other topics

The European Federation of Corrosion: from the past to the future

International audienceThe EFC is a federation of 38 organisations (Member Societies and Affiliate Members) with interests in corrosion based in 25 different countries within Europe and beyond. Taken together, its Member Societies represent the corrosion interests of more than 25,000 engineers and scientists. Founded in 1955, its aim is to advance the science of the corrosion and protection of materials by promoting cooperation in Europe and collaboration internationally. The EFC is registered in Belgium.The EFC Member Societies send delegates to a General Assembly which meets once a year to consider and approve policies.The administration of the Federation is in the hands of the Board of Administrators (BoA) and the scientific and technical affairs are the responsibility of the Science and Technology Advisory Committee (STAC) - members of both bodies being drawn from the EFC Member Societies.The day-to-day operation of the EFC is managed through the General Secretariat with offices in the UK, Germany and France and the Managing Officer.The EFC accomplishes its most important activities through twenty active working parties devoted to various aspects of corrosion and its prevention. The first working party, WP1 on Corrosion and Scale Inhibition was established in 1965 while the most recent, working party on Corrosion control in aerospace was formed in 2013. The working parties help to organise, singly or jointly with other working parties, strong technical sessions at EUROCORR. Other valuable activities include participation in collaborative research and testing programmes, the organisation of courses and workshops, and the preparation of reports, guidelines and proceedings for publication in the highly regarded EFC Series of 'green books' of which there are now over sixty The working parties are overseen by the Science and Technology Advisory Committee (STAC), to which all of the working party chairpersons and six other elected members belong. This is served by EFC's Scientific Secretary. Anyone with related interests is free to participate in working party meetings, which usually take place in conjunction with EUROCORR.EUROCORR, the EFC's annual conference is the flagship event of the European corrosion calendar. Attracting more than 1000 delegates, it is held in a different European country in September of each year. To date 38 of these conferences have been held and they have become noted for their high technical quality as well as the very enjoyable social programme.Important benefits available to EFC Member Societies include the opportunity to nominate candidates for the EFC Awards, which include the European Corrosion Medal, the Cavallaro Medal, and the Kurt Schwabe Prize. They can also appoint two voting members to each EFC Working Party and nominate candidates for election to the Board of Administrators, and the STAC. They can influence the direction taken by the EFC by voting at the annual EFC General Assembly. What is more, everyone who belongs to an EFC Member Society qualifies for reduced registration fees at EUROCORR and a discount on the prices of the EFC publications. European Member Societies can also submit bids to host EUROCORR conferencesThe EFC has recently expanded its horizons beyond the confines of Europe by admitting International Member Societies. Furthermore, companies and research organisations/ universities may join the Federation as Affiliate Members. The Federation has also become a founder member of the World Corrosion Organisation, a prime aim of which is to increase public and political awareness of corrosion and to advise governments, industries and communities about corrosion and its mitigation.The Young EFC is an initiative created in 2016 by the European Federation of Corrosion (EFC) who aims to support young researchers and engineers in the field of corrosion and protection of materials. Our vision has several cornerstones, namely: Building a bridge between young corrosion researchers and senior experts, Creating a network of young corrosionists, Organising and participating in conferences, workshops and other events, Promoting the interests of young researchers to the European Federation of Corrosion and the European Commission, Supporting the career at an early stag

Validation of a roll decay test of an offshore installation vessel using OpenFOAM

status: accepte

Validation of freely floating boxes responding to waves using the overset mesh method in OpenFOAM

status: accepte

Roll damping simulations of an offshore heavy lift DP3 installation vessel using the CFD toolbox OpenFOAM

status: publishe

Validation of a roll decay test of an offshore installation vessel using OpenFOAM

status: publishe