Incidental gastric glomus tumor after laparoscopic sleeve gastrectomy

Gastric glomus tumors (GGTs) are unusual benign, subepithelial, mesenchymal neoplasms of modified smooth muscle cells representing a neoplastic counterpart of glomus bodies. A 38-year-old woman was admitted to our clinic presenting morbid obesity. Routine preoperative evaluations, such as laboratory analysis, abdominal ultrasonography, and upper gastrointestinal endoscopy, were performed. She underwent a classical laparoscopic sleeve gastrectomy (LSG). The postoperative course was uneventful and she was discharged for outpatient control. Her histopathology report revealed a GGT 0.8 cm in diameter. No further treatment was done and she had lost 28 kg at the postoperative sixth month. Here, we present the case of GGT, which was diagnosed incidentally after LS

Incidental gastric glomus tumor after laparoscopic sleeve gastrectomy

Gastric glomus tumors (GGTs) are unusual benign, subepithelial, mesenchymal neoplasms of modified smooth muscle cells representing a neoplastic counterpart of glomus bodies. A 38-year-old woman was admitted to our clinic presenting morbid obesity. Routine preoperative evaluations, such as laboratory analysis, abdominal ultrasonography, and upper gastrointestinal endoscopy, were performed. She underwent a classical laparoscopic sleeve gastrectomy (LSG). The postoperative course was uneventful and she was discharged for outpatient control. Her histopathology report revealed a GGT 0.8 cm in diameter. No further treatment was done and she had lost 28 kg at the postoperative sixth month. Here, we present the case of GGT, which was diagnosed incidentally after LS

The effect of carnitine on kidney cold ischemic injury

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.YÖK Tez No: 242285Amaç: University of Wisconsin solüsyonunun soguk iskemiye karsı korumadaaltın standart olarak kabul edilmesine ragmen, soguk iskemi zamanının arttırılmasınıamaçlayan çalısmalar devam etmektedir. Bu deneysel çalısma, böbrek sogukiskemisinde karnitinin koruyuculugunu arastırmak için planlandı.Yöntem: Yirmi dört Wistar-Albino sıçan kontrol grubu (n=6; Ringer Laktat),karnitin ilave edilmis Ringer Laktat (n=6), University of Wisconsin (n=6) ve karnitinilave edilmis University of Wisconsin (n=6) grubu olmak üzere dörde ayrıldı.Böbreklerin saklama solüsyonuyla perfüzyonu sonrasında organlar 10ml'lik saklamasolüsyonlarına konuldu. 0,24,48,72. saatlerde saklama solüsyonunda Laktatdehidrogenaz aktiviteleri ölçüldü. Aynı zamanda 72. saatte alınan doku örneklerindeMalondialdehid degerleri çalısıldı. Doku zedelenmesi histopatolojik olarakHemotoksilen-eosinle boyanmıs parafin bloklardan alına kesitlerin(0.4?m)incelenmesi ile degerlendirilip skorlandı.Bulgular: Karnitin+ University of Wisconsin grubunda ortalama dokuMalondialdehid degeri belirgin olarak düsük bulundu (15,79±5,15'e karsı9,60±2,59nMol/mg, p=0,001) Saklama sıvılarındaki Laktat Dehirogenaz seviyelerindebelirgin bir farklılık izlenmedi. Histopatolojik incelemede karnitin ilave edilmis RingerLaktat grubunun toplam zedelenme skoru düsük olarak bulundu.Sonuçlar: University of Wisconsin solüsyonuna karnitinin eklenmesi böbreksoguk iskemisinde hasarı azaltıcı etkiyi artırmaktadır.Background and aim: However, University of Wisconsin solution is acceptedas the gold standart in the preservation from cold ischemia injury, studies that wasaiming to prolong the cold ischemia time is stil persist. This experimental study isaiming to investigate the effect of carnitine on kidney cold ischemic ınjuryMethods: Twenty four Wistar-Albino rats were divided to four groups as;control group (n=6; Ringer lactate), Ringer lactate with carnitine (n=6), University ofWisconsin (n=6) and University of Wisconsin with carnitine (n=6). After the perfusionof the kidneys with preservation solution, they put into the preservation solutionsabout 10ml. Lactate Dehydrogenase levels at 0th,24th,48th,72th hours weremeasured. At the same time Malondialdehyde levels were measured from tissuesamples that were taken at the 72th hour. To determine the tissue injury, the slices(0.4?m) that were taken from parafin blocks stained with Haemotoxilen-eosin werehistopathologically scored.Results: Mean tissue Malondialdehyde levels were significantly low in thegroup; Carnitine with University of Wisconsin (15,79±5,15 vs 9,60±2,59 nMol/mg,p=0,001) There were no significant differences in Lactate Dehydrogenase levelsbetween preservative solutions. At the histopathological evaluation, total tissue injuryscore was found low at the carnitine with Ringer lactate group.Conclusion: Supplemention of carnitine to University of Wisconsin solutionincrease the detractive effect of cold ischemic injury of kidney

CLINICAL IMPORTANCE OF SOLITARY SOLID NODULE OF THE THYROID IN ENDEMIC GOITER REGION

Context: Endemic area and iodine supplementation may affect the pathogenesis of the nodule which commonly occurs in endemic thyroid enlargement due to iodine deficiency. Aims: To establish pathological changes in solitary solid and larger nodule of the thyroid in endemic area. Setting and Design: Retrospective study in Surgical Department of University Hospital. Methods and Material: We determined 44 surgically treated patients with solitary solid nodule in endemic goiter area in which the population routinely receives iodinated salt. The thyroid nodule was preoperatively evaluated with blood chemistry, ultrasound, nuclear scanning and FNAC. The results of preoperative evaluation, surgical interventions, and histopathological examination were analyzed. Statistical analysis: Student t test and Fisher′s exact test. Results: Twenty (45%;20/44) patients with hot (autonomous) nodule have received the diagnosis of toxic adenoma. Twenty four patients had solitary solid and cold nodule. Total thyroidectomy was performed on two patients with papillary cancer (PTC) diagnosed by FNAC from cold nodules. Forty two patients have been treated with total excision of the lobe including hyper or hypoactive solitary solid nodule. Pathological examination has reported two more cases of PTC and one case of insular cancer arising from cold nodules. Completion thyroidectomy was performed on these 3 patients. Conclusions: Solitary solid and large nodule is a common indication for thyroid surgery in endemic goiter area. High incidence of hyperthyroidism due to single autonomous nodule, and high rate of malignant change (mainly papillary cancer) in solitary hypoactive nodule arises from this series in endemic thyroid enlargement

Bir akt ileus olgusunda apendiko-ileal fistül

Appendiko-ileal fistül akut ileus tablosu ile nadir görülür. Bu yazıda mekanik barsak tıkanıklığı nedeni ile laparatomi uygulanan apendikoileal fistüllü 46 yaşında erkek olgu sunuldu. Cerrahi sırasında apendiks lümeni ile terminal ileum arasında bir fistül olduğu gözlendi. Ayrıca proksimal ileal ve jejunal ansların gergin olduğu da saptandı. Apendektomi, segmental ileum rezeksiyonu ve uçuca anastomoz cerrahi işlem olarak uygulandı. İnce barsak tıkanıklığı ile akut ileus tablosu gelişen hastalarda, apendiko-ileal fistülün akılda bulunması gerektiğini düşünmekteyiz.Appendico-ileal fistula is a rare condition with acute ileus. We report a case of appendico-ileal fistule in a 46-year-old man patient who has undergone laparatomy for intestinal mechanical obstruction. Intraoperatively, an appendix with a lumen was found with a fistula to the terminal ileum. It has been observed that proximal ileal and jejunal intestinal anses were distended. Appendectomy, segmental ileum resection and end-to-end anastomoses were performed as a surgical procedure. This case describes an elderly man with acute ileus presenting with small bowel obstruction. We conclude that, appendico-ileal fistula should be kept in mind in cases with acute ileus presenting with small bowel obstruction

Ameliyat sonrasi karin içi yapişiklik oluşumunda ba?irsak kan akimindaki de?işiklikler ve endotelin-1 blo?unun rolü

PubMed ID: 16676248BACKGROUND: The current study was planned to investigate intestinal blood flow alterations and the role of ET-1 receptor blockade in the formation of postoperative intraperitoneal adhesion formation. METHODS: Twenty-eight adult Wistar Albino rats weighing between 250 g and 300 g were divided into four groups. Control group (group 1; n=7) did not undergo any operation. Sham group (group 2; n=7) had only laparotomy. In the adhesion group (group 3; n=7), peritoneal patch (1x1 cm) excision from the right abdominal wall and cecal abrasion were done as "adhesion model operation". One week following this, treatment group (group 4; n=7) received a non-selective ET-1 receptor blocking agent bosentan (30 mg/kg, IP) intra-abdominally, once a day for four days. Intestinal blood flow through the superior mesenteric artery was measured, on postoperative seventh day. Adhesion severity and extension as well as myeloperoxidase activity in the adhesion were calculated. RESULTS: Mean intestinal blood flow significantly increased in adhesion group (81.9±5.6 ml/100 g) when compared to group 1 (65.5±1.2 ml/100 g). Bosentan caused a significant decrease (44.3±6.9 ml/100 g) in intestinal blood flow when compared to group 1 and group 2. Sham group (62.2±1 ml/100 g) had similar blood flow level with the control group (65.5±1.2 ml/100g). Adhesion scores were similar in adhesion and Bosentan groups. Sham group had almost no adhesions. Myeloperoxidase activity in adhesion tissue was significantly higher in bosentan group. CONCLUSION: Non-selective ET-1 receptor blockade has no effect on prevention of the formation of intra-abdominal adhesion, but causes a decrease in intestinal blood flow. Adhesion formation increases intestinal blood flow. Adhesion formation is accompanied by increased polymorphonuclear infiltration despite bosentan treatment

Does melatonin alleviate cold preservation injury of the liver?

Coskun, Abdurrahman/0000-0002-1273-0604;WOS: 000280566800019Aim: To investigate the effect of melatonin added to preservation solution on liver cold ischemia Materials and methods: Twenty male Wistar albino rats were divided equally into groups treated with University of Wisconsin (UW) solution with and without melatonin The LDH, AST, and ACP activities of the preservation solutions were determined in samples collected at 2, 24, 36, and 48 h Tissue malondialdehyde and heat shock protein (HSP 70) levels were also measured and a histological examination was performed at 48 h Results: Melatonin prevented enzyme elevation, induced heat shock protein (HSP 70), and decreased lipid peroxidation effectively in comparison to the control group (P < 0.05) The histological examination revealed that UW solution containing melatonin prevented Kupffer cell activation and inflammation significantly (P < 0.05) Conclusion: Melatonin in preservation solutions such as UW solution may protect tissue effectively from damage during cold ischemia for up to 48 hAbant Izzet Baysal University Department of Scientific and Research Projects, Bolu, TurkeyAbant Izzet Baysal University [2005-07-01-236]This study was supported by Abant Izzet Baysal University Department of Scientific and Research Projects (2005-07-01-236), Bolu, Turkey

Inflammatory fibrosarcoma: A rare tumor involving retroperitoneum, ileum and colon

An inflammatory fibrosarcoma is a rare tumor with a varied biological behavior, from benign to locally aggressive and occasionally malignant. It generally involves mesentery and retroperitoneal structures, but it rarely can involve the hollow viscera and commonly affects children and young adults. We report a case of inflammatory fibrosarcoma affecting an unusual age group, involving the ileum and descending colon (a rare site) causing subacute intestinal obstruction. We also discuss its surgical management, differential diagnosis and review of current literature

Multiple bowel perforations in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a connective tissue disorder that has rarely been seen with acute surgical manifestations. Intestinal perforation is one of the most devastating complications of SLE which necessitates prompt surgical intervention. We report a case having multiple intestinal perforations on exploration and has undergone primary repair. SLE should be taken into account as a diagnosis of choice in patients with bowel perforation