756 research outputs found

    European periphery crises, international financial markets, and democracy: moving towards a globalized neofeudalism?

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    This paper analyzes the origin and causes of the recent economic and financial crises, mainly for the countries located in the periphery of the European Union (EU), as well as their evolution and transformation into social, political, and institutional crises. After explaining the differential impact of the crises on EU member economies and critically analysing the unsuccessful orthodox neoclassical policies implemented by governments and international institutions to try to manage and resolve them, we propose some alternative economic policy measures for the EU. Furthermore, we analyze how the economic policies developed thus far not only are unable to resolve the current crisis pattern but also actually entail a risk to the present democratic models by transferring the legitimate control over governments from citizens and democratic parliaments to unelected, non-representative international financial markets.

    Carbon and nitrogen allocation and partitioning in traditional and modern wheat genotypes under pre-industrial and future CO2 conditions

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    The results of a simultaneous 13C and 15N labelling experiment with two different durum wheat cultivars, Blanqueta (a traditional wheat) and Sula (modern), are pre- sented. Plants were grown from the seedling stage in three fully controllable plant growth chambers for one growing season and at three different CO2 levels (i.e. 260, 400 and 700 ppm). Short-term isotopic labelling (ca. 3 days) was performed at the anthesis stage using 13CO2 supplied with the chamber air and 15NH4-15NO3 applied with the nutrient solution, thereby making it possible to track the allocation and par- titioning of 13C and 15N in the different plant organs. We found that photosynthesis was up-regulated at pre-industrial CO2 levels, whereas down-regulation occurred under future CO2 conditions. 13C labelling revealed that at pre-industrial CO2 carbon investment by plants was higher in shoots, whereas at future CO2 levels more C was invested in roots. Furthermore, the modern genotype invested more C in spikes than did the traditional genotype, which in turn invested more in non-reproductive shoot tissue. 15N labelling revealed that the modern genotype was better adapted to assimi- lating N at higher CO2 levels, whereas the traditional genotype was able to assimilate N more efficiently at lower CO2 levels

    Endpoint estimates for bilinear pseudodifferential operators with symbol in BS^m_{1,1}

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    In this paper we establish some endpoint estimates for bilinearpseudodifferential operators with symbol in the class BS^m_{1,1}, involving the space of functions with local bounded mean oscillation bmo. As a consequence we also obtain an endpoint estimate of Kato-Ponce type.Comment: This is an improvement of the old version, following suggestion of anonymous referee(s

    The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases

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    The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1191782/ full#supplementary-materialInterleukin-17 family (IL-17s) comprises six structurally related members (IL-17A to IL-17F); sequence homology is highest between IL-17A and IL-17F, displaying certain overlapping functions. In general, IL-17A and IL-17F play important roles in chronic inflammation and autoimmunity, controlling bacterial and fungal infections, and signaling mainly through activation of the nuclear factor-kappa B (NF-ÎșB) pathway. The role of IL-17A and IL-17F has been established in chronic immune-mediated inflammatory diseases (IMIDs), such as psoriasis (PsO), psoriatic arthritis (PsA), axial spondylarthritis (axSpA), hidradenitis suppurativa (HS), inflammatory bowel disease (IBD), multiple sclerosis (MS), and asthma. CD4+ helper T cells (Th17) activated by IL-23 are well-studied sources of IL-17A and IL-17F. However, other cellular subtypes can also produce IL-17A and IL-17F, including gamma delta (γΎ) T cells, alpha beta (αÎČ) T cells, type 3 innate lymphoid cells (ILC3), natural killer T cells (NKT), or mucosal associated invariant T cells (MAIT). Interestingly, the production of IL-17A and IL-17F by innate and innate-like lymphocytes can take place in an IL-23 independent manner in addition to IL-23 classical pathway. This would explain the limitations of the inhibition of IL-23 in the treatment of patients with certain rheumatic immune-mediated conditions such as axSpA. Despite their coincident functions, IL-17A and IL-17F contribute independently to chronic tissue inflammation having somehow non-redundant roles. Although IL-17A has been more widely studied, both IL-17A and IL-17F are overexpressed in PsO, PsA, axSpA and HS. Therefore, dual inhibition of IL-17A and IL-17F could provide better outcomes than IL-23 or IL-17A blockade.UCB Pharma S

    “Está de bárbaros el país”, un ejemplo de crónica martiana

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    Not available.Se hace un anĂĄlisis de una de las muchas “escenas norteamericanas” que MartĂ­ redactĂł entre 1881 y 1891, las cuales constituyen en conjunto su mĂĄs abundante serie de textos. Se seleccionĂł la fechada el 9 de julio de 1889, enviada al periĂłdico La NaciĂłn de Buenos Aires, que corresponde a un momento de indudable madurez en el autor. Con ocho variadas noticias tomadas de la realidad estadounidense mĂĄs inmediata, MartĂ­ enhebra una crĂłnica a la cual la premura periodĂ­stica no le hace perder coherencia ideolĂłgica ni efectividad artĂ­stica. El hilo conductor lo encuentra MartĂ­ en la reiteraciĂłn de la violencia, dada ya en el mismo comienzo, que de hecho puede constituirse en su tĂ­tulo: “EstĂĄ de bĂĄrbaros el paĂ­s”. Pero junto con elementos que tienden a la unidad estructural del texto, el autor pone en prĂĄctica su propio aserto sobre que “con las zonas se cambia de atmĂłsfera, y con los asuntos de lenguaje”, que lo lleva a trabajar una gran variedad de matices y sutilezas en la expresiĂłn adecuada de cada noticia, cosa que le confiere a la crĂłnica entera una riqueza y trascendencia capaz de sorprendernos aĂșn hoy dĂ­a

    Caryophyllales 2015 in Berlin and the Global Caryophyllales Initiative

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    Fil: Arias, Salvador. Universidad Nacional Autónoma de México; MéxicoFil: Berendsohn, Walter G.. Freie UniversitÀt Berlin; AlemaniaFil: Borsch, Thomas. Freie UniversitÀt Berlin; AlemaniaFil: Flores Olvera, Hilda. Universidad Nacional Autónoma de México; MéxicoFil: Ochoterena, Helga. Universidad Nacional Autónoma de México; MéxicoFil: von Mering, Sabine. Freie UniversitÀt Berlin; AlemaniaFil: Zuloaga, Fernando Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Botånica Darwinion. Academia Nacional de Ciencias Exactas, Físicas y Naturales. Instituto de Botånica Darwinion; Argentin

    Use of hydrodynamic cavitation for volatile removal compound

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    © 2017. This version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/Hydrodynamic cavitation and its feasibility for volatile compound removal in enclosed channels is discussed in this paper. Very high Reynolds numbers are needed to rupture liquid by decreasing its pressure below its saturated vapour pressure. Hence, a simple stratified flow, at which the two phases separate, is precluded in vertical and horizontal tubes, where turbulence stresses will be much larger than the buoyant forces. The most probable flow regime at this high turbulence regime is a bubble- or annular flow, where the volatile matter tends to concentrate in the centre of the pipe because of the lift force resulting from the unequal flow of the viscous liquid around the bubbles in the presence of the pipe wall. Therefore, boiling the volatile matter for volatile compound removal is not enough if hydrodynamic cavitation is pursued. The attainable efficiency must also be assessed. An expression for the volatile removal efficiency and the main parameters affecting this efficiency were derived by utilising a simplified geometrical and physical model. The efficiency was found to approximate a power law as a function of the volatile concentration and its strong dependence on the size of the volatile bubble reasonably well. This result implied the need of bubble growth and the limitation of the process for highly concentrate compounds to a few percent concentrations. With regard to energetic requirements, both thermal and hydrodynamic cavitations are quantitatively similar. Furthermore, the choice of one or another corresponds more to the kind of energy source available.Peer ReviewedPostprint (author's final draft

    The brinesiphon: a homolog of the thermosiphon driven by induced salinity and downward heat transfer

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    © 2017. This version is made available under the CC-BY-NC-ND 4.0 licenseThe basis of a novel method for passive solar water heating homologous to the thermosiphon but driven by induced salinity, which causes a fluid to circulate without the need for a mechanical pump and with inverse natural convection (downward heat transfer), is outlined. The brinesiphon, like the thermosiphon, operates by harnessing the tendency of a less dense fluid to rise above a denser fluid, resulting in fluid motion through a collector, but with two exceptions: first, the buoyancy is controlled by induced salinity gradients rather than thermal gradients, and second, as a result, natural convection is in the opposite direction than that in the homologous thermosiphon concept; i.e., hot fluid flows down, and cold fluid rises. A brinesyphon may be more suitable for solar domestic water heating systems than the thermosiphon because the direction of flow allows downward transfer from a solar collector to a lower storage tank without any type of mechanical pumping system.Peer ReviewedPostprint (author's final draft
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