Physical Activity to Improve Erectile Function:A Systematic Review of Intervention Studies

Abstract Introduction The leading cause of erectile dysfunction (ED) is arterial dysfunction, with cardiovascular disease as the most common comorbidity. Therefore, ED is typically linked to a web of closely interrelated cardiovascular risk factors such as physical inactivity, obesity, hypertension, and metabolic syndrome. Physical activity (PA) has proved to be a protective factor against erectile problems, and it has been shown to improve erectile function for men affected by vascular ED. This systematic review estimated the levels of PA needed to decrease ED for men with physical inactivity, obesity, hypertension, metabolic syndrome, and/or manifest cardiovascular diseases. Aim To provide recommendations of levels of PA needed to decrease ED for men with physical inactivity, obesity, hypertension, metabolic syndrome, and/or cardiovascular diseases. Methods In accord with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a systematic review was performed of research articles specifically investigating PA as a possible treatment of ED. The review included research on ED from physical inactivity, obesity, hypertension, metabolic syndrome, and/or cardiovascular diseases. All available studies from 2006 through 2016 were checked for the predetermined inclusion and exclusion criteria to analyze the levels of PA needed to decrease ED. Results 10 articles met the inclusion criteria, all suggesting various levels of PA needed to decrease ED for men with relevant risk factors for ED. The results of the review provided sufficient research evidence for conclusions regarding the levels of PA necessary to decrease ED. Conclusion Recommendations of PA to decrease ED should include supervised training consisting of 40 minutes of aerobic exercise of moderate to vigorous intensity 4 times per week. Overall, weekly exercise of 160 minutes for 6 months contributes to decreasing erectile problems in men with ED caused by physical inactivity, obesity, hypertension, metabolic syndrome, and/or cardiovascular diseases. </jats:sec

Konsten att anpassa sin affärsmodell efter den offentliga sektorn

Syfte: Studiens syfte är att öka förståelsen för hur man som leverantör kan agera på en offentlig marknad genom att anpassa sin affärsmodell efter kundens inköpsprocesser. Metod: Genom en kvalitativ studie med inslag av både deduktiv och induktiv karaktär genomfördes semi-strukturerade intervjuer med personer på olika nivåer i inköpsprocessen i den offentliga sektorn. Urvalsramen för studien är vården i Region Skåne. Det insamlade empiriska materialet analyserades med hjälp av affärsmodellen. Teoretiska perspektiv: Affärsmodellen är en övergripande modell som inkluderar ett företags kunder, konkurrenter med mera för att beskriva hur ett företag skapar, levererar och fångar värde (Teece, 2010). Olika teorier om affärsmodellen har tagits upp men studien utgår från Hedman och Kallings (2002) sju komponenter som deras affärsmodell består av vilka är kunder, konkurrenter, erbjudande, aktiviteter och organisation, resurser och kompetenser, faktormarknad och leverantörer och ledningsprocesser. Empiri: Vårdbranschen är en av de största delarna i den offentliga sektorn och det sker ständigt nya inköp i denna. Olika perspektiv på inköp har inkluderats för att ta reda på hur man som leverantör kan anpassa sig till den offentliga vården. Personer har intervjuats från högst beslutsfattande inom regionen till operativ nivå och avslutningsvis intervjuat en branschorganisation som fått representera leverantörers perspektiv. Resultat: Studien har resulterat i ett antal rekommendationer för hur en leverantör kan anpassa sin affärsmodell till den offentliga sektorn för att öka sin lönsamhet

Infection with cagA- and vacA-positive and -negative strains of Helicobacter pylori in a mouse model

To study the role of cytotoxin-associated protein (cagA) and vacuolating cytotoxin (vacA) in Helicobacter pylori infection in an experimental murine model, mice were infected with seven strains with different cagA and vacA status. Groups of 10 NMRI mice were challenged and were killed 5 weeks later. In a second study, 20 mice were challenged with a mixture of the same seven strains and killed 1, 3, 15 and 17 weeks post-inoculation. All seven strains were found to colonize the mice for the 5-week experimental period. Animals infected with vacA-positive strains, regardless of cagA status, showed an elevation of antibody titers. Two cagA-negative and vacA-positive strains and one cagA- and vacA-positive strain were found to 'take over' in the mixed infection as analyzed by the randomly amplified polymorphic DNA-polymerase chain reaction technique and in one mouse stomach we found coexistence of two of the strains. We found no evidence of the different strains colonizing different parts of the stomach

Physical Activity to Improve Erectile Function: A Systematic Review of Intervention Studies

Introduction: The leading cause of erectile dysfunction (ED) is arterial dysfunction, with cardiovascular disease as the most common comorbidity. Therefore, ED is typically linked to a web of closely interrelated cardiovascular risk factors such as physical inactivity, obesity, hypertension, and metabolic syndrome. Physical activity (PA) has proved to be a protective factor against erectile problems, and it has been shown to improve erectile function for men affected by vascular ED. This systematic review estimated the levels of PA needed to decrease ED for men with physical inactivity, obesity, hypertension, metabolic syndrome, and/or manifest cardiovascular diseases. Aim: To provide recommendations of levels of PA needed to decrease ED for men with physical inactivity, obesity, hypertension, metabolic syndrome, and/or cardiovascular diseases. Methods: In accord with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a systematic review was performed of research articles specifically investigating PA as a possible treatment of ED. The review included research on ED from physical inactivity, obesity, hypertension, metabolic syndrome, and/or cardiovascular diseases. All available studies from 2006 through 2016 were checked for the predetermined inclusion and exclusion criteria to analyze the levels of PA needed to decrease ED. Results: 10 articles met the inclusion criteria, all suggesting various levels of PA needed to decrease ED for men with relevant risk factors for ED. The results of the review provided sufficient research evidence for conclusions regarding the levels of PA necessary to decrease ED. Conclusion: Recommendations of PA to decrease ED should include supervised training consisting of 40 minutes of aerobic exercise of moderate to vigorous intensity 4 times per week. Overall, weekly exercise of 160 minutes for 6 months contributes to decreasing erectile problems in men with ED caused by physical inactivity, obesity, hypertension, metabolic syndrome, and/or cardiovascular diseases.Gerbild H, Larsen CM, Graugaard C, Areskoug Josefsson K. Physical Activity to Improve Erectile Function: A Systematic Review of Intervention Studies. Sex Med 2018;6:75–89. Key Words: Erectile Dysfunction, Sexual Health, Rehabilitation, Lifestyle Intervention, Physiotherapy, Systematic Revie

Power, Myths, Materiality: A Multilingual Reflection over the Conditions for Knowledge Production in Times of Political Turbulence

During 2016 to 2018 the research node “Science, validation, partial perspectives: Knowledge production beyond the norms,” create spaces for transdisciplinary meetings at Uppsala university. In spring of 2017, the node arranged a journey to California in the USA, for MA candidates, PhD candidates, lecturers, and researchers. The aim was to meet with academics, activists, and artists to discuss the conditions for knowledge production in relation to the current political situation, in which ideas of “post truth” and “alternative facts” have surfaced. We visited the Scandinavian Studies and the Gender and Women’s Studies departments at UC Berkeley, and the Science and Justice Research Center at UC Santa Cruz. This multilingual essay, written in the months following the trip, is a collective, rhizomatic reflection over the relationship between narratives, cultural identities and truths; privilege and politics; language and reality; art and science; potential and risk in boundarycrossing encounters.Camilla Wallin Bergström heter numera Camilla Wallin Lämsä</p

Power, Myths, Materiality: A Multilingual Reflection over the Conditions for Knowledge Production in Times of Political Turbulence

During 2016 to 2018 the research node “Science, validation, partial perspectives: Knowledge production beyond the norms,” create spaces for transdisciplinary meetings at Uppsala university. In spring of 2017, the node arranged a journey to California in the USA, for MA candidates, PhD candidates, lecturers, and researchers. The aim was to meet with academics, activists, and artists to discuss the conditions for knowledge production in relation to the current political situation, in which ideas of “post truth” and “alternative facts” have surfaced. We visited the Scandinavian Studies and the Gender and Women’s Studies departments at UC Berkeley, and the Science and Justice Research Center at UC Santa Cruz. This multilingual essay, written in the months following the trip, is a collective, rhizomatic reflection over the relationship between narratives, cultural identities and truths; privilege and politics; language and reality; art and science; potential and risk in boundarycrossing encounters.Camilla Wallin Bergström heter numera Camilla Wallin Lämsä</p