2,462 research outputs found
Sexually Transmitted Infections and Sexual Behaviour Among Commercial Sex Workers in a Rural District of Malawi.
In Thyolo District, Malawi, a study was conducted among commercial sex workers (CSWs) attending mobile clinics in order to; determine the prevalence and pattern of sexually transmitted infections (STIs), describe sexual behaviour among those who have an STI and identify risk factors associated with 'no condom use'. There were 1817 CSWs, of whom 448 (25%) had an STI. Of these, the commonest infections included 237 (53%) cases of abnormal vaginal discharge, 109 (24%) cases of pelvic inflammatory disease and 95 (21%) cases of genital ulcer disease (GUD). Eighty-seven per cent had sex while symptomatic, 17% without condoms. Having unprotected sex was associated with being married, being involved with commercial sex outside a known rest-house or bar, having a GUD, having fewer than two clients/day, alcohol intake and having had no prior medication for STI. The high levels of STIs, particularly GUDs, and unprotected sex underlines the importance of developing targeted interventions for CSWs and their clients
Reconstructing emission from pre-reionization sources with cosmic infrared background fluctuation measurements by the JWST
We present new methodology to use cosmic infrared background (CIB)
fluctuations to probe sources at 10<z<30 from a JWST/NIRCam configuration that
will isolate known galaxies to 28 AB mag at 0.5--5 micron. At present
significant mutually consistent source-subtracted CIB fluctuations have been
identified in the Spitzer and Akari data at 2--5 micron, but we demonstrate
internal inconsistencies at shorter wavelengths in the recent CIBER data. We
evaluate CIB contributions from remaining galaxies and show that the bulk of
the high-z sources will be in the confusion noise of the NIRCam beam, requiring
CIB studies. The accurate measurement of the angular spectrum of the
fluctuations and probing the dependence of its clustering component on the
remaining shot noise power would discriminate between the various currently
proposed models for their origin and probe the flux distribution of its
sources. We show that the contribution to CIB fluctuations from remaining
galaxies is large at visible wavelengths for the current instruments precluding
probing the putative Lyman-break of the CIB fluctuations. We demonstrate that
with the proposed JWST configuration such measurements will enable probing the
Lyman break. We develop a Lyman-break tomography method to use the NIRCam
wavelength coverage to identify or constrain, via the adjacent two-band
subtraction, the history of emissions over 10<z<30 as the Universe comes out of
the 'Dark Ages'. We apply the proposed tomography to the current Spitzer/IRAC
measurements at 3.6 and 4.5 micron, to find that it already leads to
interestingly low upper limit on emissions at z>30.Comment: ApJ, in press. Minor revisions/additions to match the version in
proof
Solutions of the Klein-Gordon equation on manifolds with variable geometry including dimensional reduction
We develop the recent proposal to use dimensional reduction from the
four-dimensional space-time D=(1+3) to the variant with a smaller number of
space dimensions D=(1+d), d < 3, at sufficiently small distances to construct a
renormalizable quantum field theory. We study the Klein-Gordon equation on a
few toy examples ("educational toys") of a space-time with variable special
geometry, including a transition to a dimensional reduction. The examples
considered contain a combination of two regions with a simple geometry
(two-dimensional cylindrical surfaces with different radii) connected by a
transition region. The new technique of transforming the study of solutions of
the Klein-Gordon problem on a space with variable geometry into solution of a
one-dimensional stationary Schr\"odinger-type equation with potential generated
by this variation is useful. We draw the following conclusions: (1) The signal
related to the degree of freedom specific to the higher-dimensional part does
not penetrate into the smaller-dimensional part because of an inertial force
inevitably arising in the transition region (this is the centrifugal force in
our models). (2) The specific spectrum of scalar excitations resembles the
spectrum of the real particles; it reflects the geometry of the transition
region and represents its "fingerprints". (3) The parity violation due to the
asymmetric character of the construction of our models could be related to
violation of the CP symmetry.Comment: laTeX file, 9 pages, 8 figures. Significant corrections in the title,
abstract, text. Corrected formulas and figures. Added new references,
amendments in English. Acceptred for publication in Theoretical and
Mathematical Physics. To appear in vol. 167, may 201
Dichotomous Hamiltonians with Unbounded Entries and Solutions of Riccati Equations
An operator Riccati equation from systems theory is considered in the case
that all entries of the associated Hamiltonian are unbounded. Using a certain
dichotomy property of the Hamiltonian and its symmetry with respect to two
different indefinite inner products, we prove the existence of nonnegative and
nonpositive solutions of the Riccati equation. Moreover, conditions for the
boundedness and uniqueness of these solutions are established.Comment: 31 pages, 3 figures; proof of uniqueness of solutions added; to
appear in Journal of Evolution Equation
Voluntary Counselling, HIV Testing and Adjunctive Cotrimoxazole Reduces Mortality in Tuberculosis Patients in Thyolo, Malawi.
OBJECTIVES: To assess the feasibility and effectiveness of voluntary counselling, HIV testing and adjunctive cotrimoxazole in reducing mortality in a cohort of tuberculosis (TB) patients registered under routine programme conditions in a rural district of Malawi. DESIGN: 'Before' and 'after' cohort study using historical controls. METHODS: Between 1 July 1999 and 30 June 2000 all TB patients were started on standardized anti-TB treatment, and offered voluntary counselling and HIV testing (VCT). Those found to be HIV-positive were offered cotrimoxazole at a dose of 480 mg twice daily, provided there were no contraindications. Side-effects were monitored clinically. End-of-treatment outcomes in this cohort (intervention group) were compared with a cohort registered between 1 July 1998 and 30 June 1999 in whom VCT and cotrimoxazole was not offered (control group). FINDINGS: A total of 1986 patients was registered in the study: 1061 in the intervention group and 925 in the control cohort. In the intervention group, 1019 (96%) patients were counselled pre-test, 964 (91%) underwent HIV testing and 938 (88%) were counselled post-test. The overall HIV-seroprevalence rate was 77%. A total of 693 patients were given cotrimoxazole of whom 14 (2%) manifested minor dermatological reactions. The adjusted relative risk of death in the intervention group compared with the control group was 0.81 (P < 0.001). The number needed to treat with VCT and adjunctive cotrimoxazole to prevent one death during anti-TB treatment was 12.5. INTERPRETATION: This study shows that VCT and adjunctive cotrimoxazole is feasible, safe and reduces mortality rates in TB patients under routine programme conditions
Low level of virological failure and drug resistance among patients receiving antiretroviral treatment under programme conditions in Maputo, Mozambique
Mexico AIDS Conference 200
Well-Posedness and Symmetries of Strongly Coupled Network Equations
We consider a diffusion process on the edges of a finite network and allow
for feedback effects between different, possibly non-adjacent edges. This
generalizes the setting that is common in the literature, where the only
considered interactions take place at the boundary, i. e., in the nodes of the
network. We discuss well-posedness of the associated initial value problem as
well as contractivity and positivity properties of its solutions. Finally, we
discuss qualitative properties that can be formulated in terms of invariance of
linear subspaces of the state space, i. e., of symmetries of the associated
physical system. Applications to a neurobiological model as well as to a system
of linear Schroedinger equations on a quantum graph are discussed.Comment: 25 pages. Corrected typos and minor change
Constraints on the Progenitor of SN 2010jl and Pre-Existing Hot Dust in its Surrounding Medium
A search for the progenitor of SN~2010jl, an unusually luminous core-collapse
supernova of Type~IIn, using pre-explosion {\it Hubble}/WFPC2 and {\it
Spitzer}/IRAC images of the region, yielded upper limits on the UV and
near-infrared (IR) fluxes from any candidate star. These upper limits constrain
the luminosity and effective temperature of the progenitor, the mass of any
preexisting dust in its surrounding circumstellar medium (CSM), and dust
proximity to the star. A {\it lower} limit on the CSM dust mass is required to
hide a luminous progenitor from detection by {\it Hubble}. {\it Upper} limits
on the CSM dust mass and constraints on its proximity to the star are set by
requiring that the absorbed and reradiated IR emission not exceed the IRAC
upper limits. Using the combined extinction-IR emission constraints we present
viable combinations, where and are the CSM dust mass and
its inner radius. These depend on the CSM outer radius, dust composition and
grain size, and the properties of the progenitor. The results constrain the
pre-supernova evolution of the progenitor, and the nature and origin of the
observed post-explosion IR emission from SN~2010jl. In particular, an
~Car-type progenitor will require at least 4~mag of visual extinction to
avoid detection by the {\it Hubble}. This can be achieved with dust masses
~\msun\ (less than the estimated 0.2-0.5~\msun\ around
~Car) which must be located at distances of ~cm from the
star to avoid detection by {\it Spitzer}.Comment: Accepted for publication in the ApJ. 14 pages 10 figures. The
complete figure set for Figure 10 (24 images) is available in the online
journa
The Berry-Keating operator on L^2(\rz_>, x) and on compact quantum graphs with general self-adjoint realizations
The Berry-Keating operator H_{\mathrm{BK}}:=
-\ui\hbar(x\frac{
\phantom{x}}{
x}+{1/2}) [M. V. Berry and J. P. Keating,
SIAM Rev. 41 (1999) 236] governing the Schr\"odinger dynamics is discussed in
the Hilbert space L^2(\rz_>,
x) and on compact quantum graphs. It is
proved that the spectrum of defined on L^2(\rz_>,
x) is
purely continuous and thus this quantization of cannot yield
the hypothetical Hilbert-Polya operator possessing as eigenvalues the
nontrivial zeros of the Riemann zeta function. A complete classification of all
self-adjoint extensions of acting on compact quantum graphs
is given together with the corresponding secular equation in form of a
determinant whose zeros determine the discrete spectrum of .
In addition, an exact trace formula and the Weyl asymptotics of the eigenvalue
counting function are derived. Furthermore, we introduce the "squared"
Berry-Keating operator which is a special case of the
Black-Scholes operator used in financial theory of option pricing. Again, all
self-adjoint extensions, the corresponding secular equation, the trace formula
and the Weyl asymptotics are derived for on compact quantum
graphs. While the spectra of both and on
any compact quantum graph are discrete, their Weyl asymptotics demonstrate that
neither nor can yield as eigenvalues the
nontrivial Riemann zeros. Some simple examples are worked out in detail.Comment: 33p
The mid-infrared colors of the interstellar medium and extended sources at the Galactic center
A mid-infrared (3.6–8 μm) survey of the Galactic center has been carried out with the IRAC instrument on the Spitzer Space Telescope. This survey covers the central 2º x 1.4º (~280 x 200 pc) of the Galaxy. At 3.6 and 4.5 μm the emission is dominated by stellar sources, the fainter ones merging into an unresolved background. At 5.8 and 8 μm the stellar sources are fainter, and large-scale diffuse emission from the ISM of the Galaxy's central molecular zone becomes prominent. The survey reveals that the 8-to-5.8 μm color of the ISM emission is highly uniform across the surveyed region. This uniform color is consistent with a flat extinction law and emission from polycyclic aromatic hydrocarbons (PAHs). Models indicate that this broadband color should not be expected to change if the incident radiation field heating the dust and PAHs is ~10^4 times that of the solar neighborhood. Other regions of very red emission indicate cases where thick dust clouds obscure deeply embedded objects or very early stages of star formation
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