ANTIBACTERIAL ACTIVITY OF BAWANG DAYAK (ELEUTHERINE SP.) AND TAWAS UT (AMPELOCISSUS SP.) FROM CENTRAL KALIMANTAN AGAINST PROPIONIBACTERIUM ACNES

Objective: The aim of the present study was to investigate phytochemical screenings and the in vitro effect antibacterial of BD (Eleutherine Sp.) and TU (Ampelocissus Sp.) against Propionibacterium acnes.Methods: The antibacterial activity was investigated against Propionibacterium acnes by well diffusion method.Results: Preliminary phytochemical screenings of BD ethanolic extract were found positive alkaloid, saponin, tannins, and steroid while TUpositive flavonoid, saponin, tannins, steroid, and triterpenoid. Antibacterial activity against Propionibacterium acnes of ethanolic extract BD with concentration 25 mg/ml and 50 mg/ml showed the zone of inhibition 3.23 mm and 7.8 mm with category weak activity while ethanolic extract TU with same concentration showed zone of inhibition 10 mm (weak activity) and 16.3 mm (moderate activity) which mean ethanolic extract TU have better antibacterial activity. A combination ethanolic extract of both with variant ratio showed a zone of inhibition 6.7 mm (1:1), 3.9 mm (1:2), and 3.63 mm (2:1).Conclusion: In this present study showed the highest potential antibacterial activity against propionibacterium acnes is an ethanolic extract of TU and The best ratio combination is 1:1. Furthermore, this study needs more research with variant concentration so that may be possible to be used as natural anti-acne formulations

Gambaran Penggunaan Obat Antihipertensi pada Pasien Preeklampsia di Instalasi Rawat Inap Rumah Sakit Bhayangkara Kota Palangka Raya Tahun 2016

Preeclampsia and eclampsia are the second rank cause of maternal mortality, and the first is bleeding. Therefore, the initial diagnosis of preeclampsia, which is the beginning of eclampsia, and its treatment needs to be immediately implemented to reduce maternal and child mortality. This study aims to know the description of antihypertensive preeclampsia in Bhayangkara Hospitals of Palangka Raya to review of an aspect of the accurate indication, the right drug, right patient, and the right dose of the reference JNC 7. This type of research is nonexperimental research. The study was done by observation which the data was taken retrospectively and analyzed by descriptive non-analytic. The result showed that the type of drug used was 80% of methyldopa, 60 % nifedipine, MgSO4 60% and of evaluation of drug use in Bhayangkara Hospitals of Palangka Raya in 2016 did not find any indication, drug, dose, and patient that not right

THE ANTIBACTERIAL ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL.) URB.) FROM CENTRAL KALIMANTAN AGAINST ACNE-CAUSING BACTERIA

Objective: The objective of this research was to investigate the antibacterial activity of bawang dayak from Central Kalimantan against acne-causingbacteria namely Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus.Methods: The preliminary phytochemical constituents were qualitatively analyzed. Antibacterial activity of bawang dayak ethanol extract wasperformed using disc-diffusion technique, with five variations of concentration of 1.25%, 2.5%, 5%, 10%, and 20%.Results: Bawang dayak extract contained flavonoids, alkaloids, saponins, and tannins. The inhibition zones of bawang dayak ethanol extract in fivevarious concentrations (1.25%, 2.5%, 5%, 10%, and 20%) were 7.0±1.3 mm, 8.5±0.6 mm, 9.9±0.3 mm, 11.2±0.1 mm, and 11.9±0.3 mm against P. acnes;18.8±3.3 mm, 21.9±3.3 mm, 20.8±0.6 mm, 22.0±0.2 mm, and 23.1±0.6 mm against S. epidermidis; and 14.3±3.1 mm, 13.5±0.9 mm, 14.7±1.5 mm,16.1±1.0 mm, and 20.1±0.6 mm against S. aureus, respectively.Conclusion: This present study showed that bawang dayak ethanol extract was active against all the tested acne-causing bacteria. The highestantibacterial activity was produced by 20% of bawang dayak ethanol extract against S. epidermidis

Tingkat Kepatuhan Minum Obat Pasien Hipertensi JKN di Poli Penyakit Dalam RSUD Dr. Doris Sylvanus Palangka Raya

Penelitian ini merupakan cross sectional study data diambil selama 1 bulan (November 2015) di poli Penyakit Dalam RSUD dr. Doris Sylvanus Palangka Raya. Pasien hipertensi yang dapat berpartisipasi adalah pasien dengan usia ≥ 18 tahun – 65 tahun. Data diperoleh dengan cara melakukan wawancara menggunakan instrument kuisioner MMAS (Morisky Medication Adherence Scale). Pada penelitian ini subyek yang memenuhi kriteria inklusi sejumlah 86 pasien. Hasil penelitian menunjukkan tingkat kepatuhan minum obat pasien hipertensi di Poli Penyakit Dalam RSUD dr. Doris Sylvanus Palangka Raya adalah tingkat kepatuhan sedang dengan score MMAS= 6,05 ± 1,94, selain itu baik usia maupun tingkat pendidikan tidak mempunyai pengaruh terhadap tingkat kepatuhan minum obat, yang dibuktikan dengan hasil uji SPSS menggunakan Kruskal Wallis Test P= 0,806 untuk usia dan P= 0,178 untuk tingkat pendidikan (P < 0,05). Pada penelitian ini dapat disimpulkan bahwa tingkat kepatuhan minum obat pasien hipertensi di poli penyakit dalam RSUD dr. Doris Sylvanus Palangka Raya periode November 2015 adalah tingkat kepatuhan sedang

Tingkat Pengetahuan Siswi SMA Muhammadiyah Palangka Raya tentang Dysmenorrhea

Dysmenorrhea is one of the most common gynecological problems in women of all ages, the incidence of dysmenorrhea in the world is very large on average more than 50% of women in every world experience it. Muhammadiyah Senior High School is one of the best schools in Palangka Raya. Based on the observations that have been done by researcher the results are many students got dysmenorrhea with severe pain and certainly this condition will disrupt daily activity, especially when teaching and learning and so extracurricular activities. Therefore, research about the level of dysmenorrhea knowledge is needed. The research method was used in this research was a descriptive method with the technique of sampling purposive sampling with 10 statements questionnaire consist of 4 indicators there is the definition of dysmenorrhea, signs, and symptoms of dysmenorrhea, causes of dysmenorrhea and how to treat and prevent dysmenorrhea. Based on the results of the study was found that the level of dysmenorrhea knowledge female students Muhammadiyah Senior High School of Palangka Raya included in the sufficient category with percentage 66,67%, meanwhile based on knowledge indicators, definition of dysmenorrhea was 73.22% (sufficient category), signs and symptoms of dysmenorrhea was 58.93% (sufficient category), causes of dysmenorrhea was 63.69% (sufficient category) and how to treat and prevent dysmenorrhea was 68.75% (sufficient category). Based on the results of this study, it can be concluded that the level of dysmenorrhea knowledge female students Muhammadiyah Senior High School of Palangka Raya included in category sufficient to know with percentage 66.67%

ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACT BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL.) URB) IN CREAM AGAINST PROPIONIBACTERIUM ACNES

Objective: The aims of this present study were to formulate antiacne cream consisting ethanolic extract of bawang dayak and evaluate antibacterialactivity of cream on day 0 and day 7 to see stability activity and preparation.Methods: Cream formula of bawang dayak was evaluated organoleptic characteristics, homogeneity, pH, adhesion test, dispersion test, and in vitroantibacterial against Propionibacterium acnes.Results: The results of evaluate cream homogeneity were F3 and F4 on day 7 separate and non-homogen but all formula pH suitable for topicalapplication. On day 0, F1 and F2 shown antibacterial activity in category weak activity, F3 and F4 in category moderate activity, while on day 7 allformula have antibacterial activity in category weak activity.Conclusion: All cream formula potentials inhibit against P. acnes but this research must be improved both of preparation and stability activity

EDUKASI PENINGKATAN PENGETAHUAN TANAMAN OBAT BAWANG DAYAK KHAS KALTENG BASED ON RESEARCH DI SEI GOHONG KALIMANTAN TENGAH

ABSTRAKProspek pengembangan tanaman obat dapat dilihat dari aspek potensi flora, iklim, tanah maupun industri obat dan kosmetika tradisional. Secara empiris, beberapa tumbuhan obat selain mempunyai keunggulan kimiawi (sebagai bahan obat) juga mempunyai keunggulan fisik (sebagai tanaman hias) dan biologis (sebagai tanaman yang dibudidayakan). Peran tanaman obat dalam pemberdayaan ekonomi dapat melalui penyediaan bahan baku, sebagai penggerak berkembangnya sektor ekonomi pedesaan, pemanfaatan sumber daya domestik, penyerapan tenaga kerja produktif di pedesaan sekaligus sebagai media untuk meratakan dan meningkatkan kesejahteraan masyarakat dan menghasilkan devisa Negara. Berdasarkan hal tersebut perlu adanya kolaborasi dengan para petani terutama petani lokal untuk meningkatkan nilai jual atau economic value bawang dayak yang didasari hasil riset. Masyarakat Sei Gohong Kecamatan Bukit Batu Palangka Raya merupakan masyarakat yang sebagian besar berprofesi sebagai petani. Pengabdian masyarakat dilakukan dengan pemberian edukasi untuk meningkatkan pengetahuan tentang tanaman obat khas Kalteng yaitu bawang dayak based on research. Berdasarkan hasil pengabdian kepada masyarakat dapat disimpulkan secara statistik adanya peningkatan pengetahuan para peserta tentang bawang dayak sebagai tanaman obat khas Kalteng berbasis riset (P=0.044<0.05). Kata kunci: bawang dayak; kalimantan tengah; pengetahuan; tanaman obat ABSTRACTThe prospect of developing medicinal plants can be seen from the potential aspects of flora, climate, soil, traditional medicine and cosmetics industry. Empirically, some medicinal plants besides having chemical advantages (as medicinal ingredients) also have physical advantages (as ornamental plants) and biological (as cultivated plants). The role of medicinal plants in economic empowerment can be through the provision of raw materials, as a driving force for the development of the rural economic sector, utilization of domestic resources, absorption of productive labor in rural areas as well as a medium for improving people’s welfare and generating state foreign exchange. Based on it, it is necessary to collaborate with farmers, especially local farmers to increase the selling value or economic value of bawang dayak based on research results. The people of Sei Gohong, Bukit Batu District, Palangka Raya are people who mostly work as farmers. Community service is carried out by providing education to improvement knowledge about medicinal plants typical of Central Kalimantan, that is bawang dayak based on research. Based on the results of community service, it can be concluded statistically that there was an increase in participants knowledge about bawang dayak as a research-based typical medicinal plant of Central Kalimantan (P=0.044<0.05).   Keywords: bawang dayak; central kalimantan; knowledge; medicinal plant

Tingkat Pengetahuan Mahasiswa D-III Farmasi tentang Bahaya Penggunaan Pewarna Rambut dalam Jangka Panjang

Pewarna rambut yang dijual bebas dipasaran beberapa memungkinkan mengandung zat mengkhawatirkan dapat berisiko bagi rambut maupun kesehatan untuk jangka panjang. Umumnya pewarna rambut mengandung zat Para-phenylendiamine (PPD) dan Hidrogen Peroksida (H2O2), zat ini tidak dilarang namun memiliki bahaya dalam jangka panjang. H2O2yang sering terkandung dalam kosmetik pewarnaan rambut membuat batang rambut tidak kuat, membuat rambut mudah rusak yang mengakibatkan batang rambut terbuka, sehingga rambut pecah-pecah, rontok, patah, dan kering. Sedangkan (PPD) yang terlapisi di kulit dapat terpenetrasi ke dalam kulit dan mengalami absorsbi secara dermal sehingga dapat menimbulkan alergi, tumor dan beberapa gangguan kesehatan lainnya. Tujuan dari penelitian ini adalah mendapatkan gambaran pengetahuan mahasiswa D-III Farmasi Universitas Muhammadiyah Palangkaraya tentang bahaya penggunaan pewarna rambut dalam jangka panjang. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif. Populasi penelitian ini yaitu seluruh mahasiswa D-III Farmasi Universitas Muhammadiyah Palangkaraya yang masih aktif baik laki-laki maupun perempuan yang berjumlah 133 responden. Sampel dihitung dengan Krejcie morgan sehingga didapatkan 99 responden. Teknik pengambilan data dengan memberikan lembar kuesioner kepada 99 responden Analisis data yang digunakan adalah teknik persentase. Analisis data yang digunakan adalah uji validitas, uji reliabilitas, dan persentase. Dari hasil penelitian diperoleh Mahasiswa D-III Farmasi Universitas Muhammadiyah Palangkaraya memiliki pengetahuan yang cukup mengenai bahaya penggunaan pewarna rambut dalam jangka panjang dengan persentase 71,57%

Tingkat Pengetahuan Pedagang Warung Tenda di Jalan Yos Sudarso Palangkaraya tentang Bahaya Penggunaan Minyak Jelantah bagi Kesehatan

Konsumsi makanan yang mengandung minyak di masyarakat cukup tinggi, makanan gorengan cenderung lebih disukai dibanding rebus. Namun, banyak yang belum mengetahui bahwa ternyata masih saja terdapat penjual gorengan yang menggunakan minyak jelantah. Berdasarkan hasil observasi yang dilakukan peneliti di lapangan, terdapat lebih dari dua pedagang yang menggunakan minyak jelantah untuk menggoreng makanan berkali-kali dengan kondisiminyak yang sudah tidak layak untuk di konsumsi. Karena pada saat observasi ditemukan adanya pedagang yang menggunakan minyak jelantah, maka peneliti tertarik untuk melakukan penelitian ini. Metode penelitian yang digunakan dalam penelitian ini adalah deskriptif. Sampel dalam penelitian ini yaitu sebesar 30 pedagang warung tenda yang menjual makanan lalapan dalam bentuk goreng. Teknik pengambilan sampel pada penelitian ini menggunakan teknik purposive sampling. Analisis data yang digunakan adalah uji validitas, uji reliabilitas, dan persentase. Dari hasil penelitian diperoleh pedagang warung tenda di jalan Yos Sudarso Palangka Raya memiliki pengetahuan yang cukup baik mengenai bahaya penggunaan minyak jelantah bagi kesehatan dengan persentase 57,92% dari 30 responden

Efek Paparan Asap Pengolahan Ikan dengan Cara di Panggang terhadap Indeks Trombosit pada Pedagang Makanan di Kota Palangka Raya

Fish processing by grilled can produce emissions that contribute to pollutants in the air, which contain toxic chemical compounds that can provide short-term and long-term effects on human health. Some studies report a positive relationship between the amount of exposure to air pollution and the platelet index. The research was conducted on the subject of grilled fish sellers in Palangka Raya (73 respondents) and the control was fish food seller without selling grilled fish (33 respondents). Measurement of platelet indices (MPV, PDW, P-LCR, and PCT) used KX300 Hematology Analyzers. The results showed a significant difference in platelet indices for MPV, PDW and P-LCR parameters in the exposed group compared to controls, with values in the exposed group higher than controls and for PCT parameters, there was no significant difference even though the exposure value was higher than the control. The content of harmful chemical compounds present in the smoke of processing grilled fish can increase platelet activation that can lead to inflammation