Odontoma composto: relato de caso / Compound odontoma: clinical case report

Os Odontomas são definidos como uma malformação benigna e são os tipos mais comum de tumores odontogênicos. De acordo com as suas características histomorfológicas podem ser classificados em composto e complexo. São assintomáticos e normalmente diagnosticados em consultas de rotinas, através de exames radiográficos associados à falta da erupção de um dente permanente. O tratamento consiste em excisão cirúrgica (enucleação e curetagem) da lesão. O objetivo do presente trabalho é descrever um caso clínico de odontoma composto localizado na região anterior da maxila, em paciente do sexo feminino, 11 anos de idade. Sendo atendida pela clínica odontológica do CESMAC. Apresentando uma lesão que estava relacionada com a retenção dentária de elementos permanentes. Sendo realizado o exame clínico, radiografia periapical e oclusal, confirmando o diagnóstico clínico e radiográfico de Odontoma Composto. O tratamento cirúrgico propiciou a remoção da lesão que não mostrou recidiva no pós-operatório. O acompanhamento do caso é de suma importância para avaliar a posterior necessidade de tracionamento ortodôntico do dente retido pela lesão

A inclusão do cirurgião dentista em ambiente hospitalar / The inclusion of dental surgeon in hospital environment

O cuidado com a saúde em âmbito hospitalar exige o trabalho em equipe multidisciplinar, fato que demandou a introdução da Odontologia nesse ambiente de trabalho. A odontologia Hospitalar tem como objetivo, dá assistência e cuidados a pacientes que se encontram sob internação hospitalar, visto que o cirurgião-dentista é um profissional capacitado para, detectar, prevenir e cuidar das alterações bucais. A inserção do CD em ambiente hospitalar tem sido instituída mediante a resoluções e leis. Sendo assim, o objetivo deste trabalho é apresentar trajetória da Odontologia Hospitalar no Brasil, verificando a situação atual e mostrar sobre a importância desse profissional na equipe multidisciplinar dos hospitais. As buscam foram feitas nas principais bases de dados na área da saúde: PubMed, Scopus e BVS (Biblioteca Virtual em Saúde). Não sendo estipulado limite para o período de busca dos artigos, bem como não houve restrição de idioma

Prevalência e etiologia do traumatismo dental entre crianças e adolescentes: revisão de literatura/ Prevalence and etiology of dental traumacism among children and adolescents: literature review

O traumatismo dentário é uma ocorrência comum na primeira infância, e é considerado pela Organização Mundial de Saúde (OMS), um problema de Saúde Pública, podendo envolver desde uma pequena fratura em esmalte até a perda definitiva do elemento dentário. O objetivo deste estudo é descrever a prevalência e média dos afetados por traumatismo entre as crianças e adolescentes, bem como as causas das injúrias dentárias traumáticas envolvendo gênero e identificando a frequência das sequelas após o traumatismo. Alguns critérios de inclusão foram estabelecidos, como: As publicações que tiveram como foco traumatismos dentais entre as crianças e os adolescentes. Após a leitura de todo material, foi procedida compreensão para análise e elaborado o referencial teórico. Para realização desse estudo bibliográfico foi efetuada pesquisas em bancos de dados MEDLINE (Medical Literature Analysis and Retrieval Sistem on-line), SCIELO (Scientific Eletronic Library on-line) e LILACS (Literatura Latino-americana e do Caribe em Ciências da Saúde) além de livros da área de traumatismo dental e saúde bucal coletiva

Antibacterial and antifungal activity of curcumin and methylene blue associated with laser on bacterial and fungal strains

Objective: To analyze the effect of methylene blue and 10% curcumin in fungi and bacteria through an in vitro study using photodynamic therapy (PDT). Methods: Curcumin and methylene blue were photosensitized by a Photon Lase III laser applied for 90 s in a dark environment within a laminar flow chamber. Enterococcus faecalis and Candida albicans strains were cultured and standardized. Then, a minimum inhibitory concentration (MIC) assay was conducted for these photosensitizers, with concentration variations and incubation to evaluate their antimicrobial activity. Results: With PDT, Curcumin had significant antibacterial activity against E. faecalis (MIC = 250 µg/mL). In contrast, methylene blue had antibacterial activity against E. faecalis (MIC < 12.5 µg/mL with PDT) and antifungal activity against C. albicans (MIC <12.5 µg/mL with or without PDT). Both agents showed greater efficacy in the presence of the laser. The results suggest that curcumin and methylene blue associated with laser may effectively treat microbial infections. Conclusion: Further research is needed to evaluate the efficacy and safety of using these agents in animal and human models and their effectiveness against different bacterial and fungal strains.

Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil

Abstract The emergence and reemergence of mosquito-borne diseases in Brazil such as yellow fever, zika, chikungunya, and dengue have had serious impacts on public health. Concerns have been raised due to the rapid dissemination of the chikungunya virus across the country since its first detection in 2014 in Northeast Brazil. In this work, we carried out on-site training activities in genomic surveillance in partnership with the National Network of Public Health Laboratories that have led to the generation of 422 chikungunya virus genomes from 12 Brazilian states over the past two years (2021–2022), a period that has seen more than 312 thousand chikungunya fever cases reported in the country. These genomes increased the amount of available data and allowed a more comprehensive characterization of the dispersal dynamics of the chikungunya virus East-Central-South-African lineage in Brazil. Tree branching patterns revealed the emergence and expansion of two distinct subclades. Phylogeographic analysis indicated that the northeast region has been the leading hub of virus spread towards other regions. Increased frequency of C > T transitions among the new genomes suggested that host restriction factors from the immune system such as ADAR and AID/APOBEC deaminases might be driving the genetic diversity of the chikungunya virus in Brazil

Implementation of a Brazilian Cardioprotective Nutritional (BALANCE) Program for improvement on quality of diet and secondary prevention of cardiovascular events: A randomized, multicenter trial

Background: Appropriate dietary recommendations represent a key part of secondary prevention in cardiovascular disease (CVD). We evaluated the effectiveness of the implementation of a nutritional program on quality of diet, cardiovascular events, and death in patients with established CVD. Methods: In this open-label, multicenter trial conducted in 35 sites in Brazil, we randomly assigned (1:1) patients aged 45 years or older to receive either the BALANCE Program (experimental group) or conventional nutrition advice (control group). The BALANCE Program included a unique nutritional education strategy to implement recommendations from guidelines, adapted to the use of affordable and regional foods. Adherence to diet was evaluated by the modified Alternative Healthy Eating Index. The primary end point was a composite of all-cause mortality, cardiovascular death, cardiac arrest, myocardial infarction, stroke, myocardial revascularization, amputation, or hospitalization for unstable angina. Secondary end points included biochemical and anthropometric data, and blood pressure levels. Results: From March 5, 2013, to Abril 7, 2015, a total of 2534 eligible patients were randomly assigned to either the BALANCE Program group (n = 1,266) or the control group (n = 1,268) and were followed up for a median of 3.5 years. In total, 235 (9.3%) participants had been lost to follow-up. After 3 years of follow-up, mean modified Alternative Healthy Eating Index (scale 0-70) was only slightly higher in the BALANCE group versus the control group (26.2 ± 8.4 vs 24.7 ± 8.6, P <.01), mainly due to a 0.5-serving/d greater intake of fruits and of vegetables in the BALANCE group. Primary end point events occurred in 236 participants (18.8%) in the BALANCE group and in 207 participants (16.4%) in the control group (hazard ratio, 1.15; 95% CI 0.95-1.38; P =.15). Secondary end points did not differ between groups after follow-up. Conclusions: The BALANCE Program only slightly improved adherence to a healthy diet in patients with established CVD and had no significant effect on the incidence of cardiovascular events or death. © 2019 The Author