Sermon en las honras que se celebraron al em\pmo\s. Sr. D. Pascual de Aragon y Cordova arçobispo de ... Toledo ... en el conv¯eto de las Madres Capuchinas de Toledo ... 13 de octubre de 1677 ...

Copia digital. Madrid : Ministerio de Cultura. Subdirección General de Coordinación Bibliotecaria, 2008Aprobación fechada en Toledo, 1677Sign.: [parágrafo]\p4\s, A-D\p4\sPort. con orla tip

Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis.

Funder: Queensland GovernmentSyphilis, which is caused by the sexually transmitted bacterium Treponema pallidum subsp. pallidum, has an estimated 6.3 million cases worldwide per annum. In the past ten years, the incidence of syphilis has increased by more than 150% in some high-income countries, but the evolution and epidemiology of the epidemic are poorly understood. To characterize the global population structure of T. pallidum, we assembled a geographically and temporally diverse collection of 726 genomes from 626 clinical and 100 laboratory samples collected in 23 countries. We applied phylogenetic analyses and clustering, and found that the global syphilis population comprises just two deeply branching lineages, Nichols and SS14. Both lineages are currently circulating in 12 of the 23 countries sampled. We subdivided T. p. pallidum into 17 distinct sublineages to provide further phylodynamic resolution. Importantly, two Nichols sublineages have expanded clonally across 9 countries contemporaneously with SS14. Moreover, pairwise genome analyses revealed examples of isolates collected within the last 20 years from 14 different countries that had genetically identical core genomes, which might indicate frequent exchange through international transmission. It is striking that most samples collected before 1983 are phylogenetically distinct from more recently isolated sublineages. Using Bayesian temporal analysis, we detected a population bottleneck occurring during the late 1990s, followed by rapid population expansion in the 2000s that was driven by the dominant T. pallidum sublineages circulating today. This expansion may be linked to changing epidemiology, immune evasion or fitness under antimicrobial selection pressure, since many of the contemporary syphilis lineages we have characterized are resistant to macrolides

Barriers to health care services for migrants living with HIV in Spain

BACKGROUND: In Spain, migrants are disproportionately affected by HIV and experience high rates of late diagnosis. We investigated barriers to health care access among migrants living with HIV (MLWH) in Spain. METHODS: Cross sectional electronic survey of 765 adult HIV-positive migrants recruited within 18 health care settings between July 2013 and July 2015. We collected epidemiological, demographic, behavioral and clinical data. We estimated the prevalence and risk factors of self-reported barriers to health care using multivariable logistic regression. RESULTS: Of those surveyed, 672 (88%) had information on health care access barriers: 23% were women, 63% from Latin America and Caribbean, 14% from Sub-Saharan Africa and 15% had an irregular immigration status. Men were more likely to report barriers than women (24% vs. 14%, P = 0.009). The main barriers were: lengthy waiting times for an appointment (9%) or in the clinic (7%) and lack of a health card (7%). Having an irregular immigration status was a risk factor for experiencing barriers for both men (OR: (4.0 [95%CI: 2.2–7.2]) and women (OR: 10.5 [95%CI: 3.1–34.8]). Men who experienced racial stigma (OR: 3.1 [95%CI: 1.9–5.1]) or food insecurity (OR: 2.1 [95%CI: 1.2–3.4]) were more likely to report barriers. Women who delayed treatment due to medication costs (6.3 [95%CI: 1.3–30.8]) or had a university degree (OR: 5.8 [95%CI: 1.3–25.1]) were more likely to report barriers. CONCLUSION: Health care barriers were present in one in five5 MLWH, were more common in men and were associated to legal entitlement to access care, perceived stigma and financial constraints

Honras que la capilla real de San Marcos de la ciudad de Salamanca celebrò a la ... Reyna ... Doña Ysabel de Borbon ... a XXII de Nouiembre de MDCXLIIII

Autor tomado de h. 1Sign.: [calderón]\p4\s, 2[calderón]\p2\s, A-D\p4\sPort. con esc. real calc.: "Jacint. Tabor.

Sermon en las honras que se celebraron al Emmo. Sr. D. Pascual de Aragon y Cordova, arçobispo de ... Toledo ... en el ... conv¯eto de las Madres Capuchinas de Toledo ... / predicòle ... Don Francisco de Arando y Mazuelo ... 13 de octubre de 1677 ...

Lugar y fecha de aprobación y licencia: Toledo, 1678Sign.: [parágrafo]\p4\s, A-D\p4\sTexto a dos col.Port. con orla tip.Enc. perg. con correillas, cortes salpicadosTexto con apostillas marginales y reclamosEnc. junto con otras obras formando un vol. facticio'Carte que escriuio... Don Pascual de Aragon... á su Santa Iglesia primada de las Españas, antes de recibir el viatico' 'Carte que escriuio... Don Pascual de Aragon... a los curas de arçobispado, antes de recibir el viatico

Sermon que en las honras que la Santa Iglesia de Toledo primada de las Españas, celebro en 7 de Octubre de 1665, al ... señor cardenal Don Balthasar de Moscoso y Sandoval su arçobispo

Sign.: A-D\p4\s, E\p3\

Do labour-managed firms benefit from agglomeration?

Panel data on the entry of labour-managed firms in the Basque Country are used to test for the presence of agglomeration externalities. A variety of controls are employed to deal with the identification problem that confronts any attempt to measure such effects. Consistent with theoretical arguments, we find evidence of positive non-industry-specific externalities among labour-managed firms. Our results do not rule out the additional presence of industry-specific externalities among such firms, but do indicate an absence of externalities flowing from capitalist to labour-managed firms