27 research outputs found

    Polymorphous adenocarcinoma of the salivary glands : reappraisal and update

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    Although relatively rare, polymorphous adenocarcinoma (PAC) is likely the second most common malignancy of the minor salivary glands (MiSG). The diagnosis is mainly based on an incisional biopsy. The optimal treatment comprises wide surgical excision, often with adjuvant radiotherapy. In general, PAC has a good prognosis. Previously, PAC was referred to as polymorphous low-grade adenocarcinoma (PLGA), but the new WHO classification of salivary gland tumours has also included under the PAC subheading, the so-called cribriform adenocarcinoma of minor salivary glands (CAMSG). This approach raised controversy, predominantly because of possible differences in clinical behaviour. For example, PLGA (PAC, classical variant) only rarely metastasizes, whereas CAMSG often shows metastases to the neck lymph nodes. Given the controversy, this review reappraises the definition, epidemiology, clinical presentation, diagnostic work-up, genetics, treatment modalities, and prognosis of PAC of the salivary glands with a particular focus on contrasting differences with CAMSG.Peer reviewe

    Physical Fitness and Metabolic Profile among Malay Undergraduates of a Public University in Selangor Malaysia

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    This study investigated health-related components of physical fitness consisting of morphological fitness (body fat % or BF %; Body Mass Index or BMI; and waist circumference or WC), metabolic fitness (blood glucose, lipid profiles and haemoglobin) and aerobic capacity (VO2max). This crosssectional study involved 324 undergraduates recruited voluntarily by systematic random sampling from a public university in the city Shah Alam, Selangor Malaysia. The respondents’ aerobic capacity was measured by field fitness tests and anthropometric measurements using standard protocols. The mean BMI of respondents was 22.51 ± 4.18 kg/m2, and majority of the respondents (93%) are within normal range of WC. The prevalence of underweight was 13.5% and overweight/obese was 20.2%. The blood glucose levels of respondents were within the normal range (94.4%) and about 5% of female respondents had moderate anaemia. More than 70% of the males and 25% of the females had poor VO2max levels (aerobic capacity). In summary, the present results suggest the necessity of health promotion programme focusing on physical activity and nutrition for university students

    Retracted: Expression of leptin-receptor (LEP-R) and Angiotensin-converting enzyme (ACE) genes after a 12-week high Intensity interval training (HIIT) intervention among obese Individuals

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    This article was withdrawn and retracted by the Journal of Fundamental and Applied Sciences and has been removed from AJOL at the request of the journal Editor in Chief and the organisers of the conference at which the articles were presented (www.iccmit.net). Please address any queries to [email protected]

    Whole Grain Intakes in the Diets Of Malaysian Children and Adolescents--Findings from the MyBreakfast Study.

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    Diets rich in whole grain are associated with several health benefits. Little is known however, about whole grain consumption patterns in Malaysia. The aim of this study was to assess whole grain intakes and dietary source in Malaysian children and adolescents.This analysis is from the MyBreakfast study, a national cross sectional study investigating eating habits among primary and secondary school children throughout Malaysia, conducted in 2013. Children (n = 5,165) and adolescents (n = 2,947) who completed two days of dietary assessment using a food record or recall respectively were included. The whole grain content of foods was estimated mainly through the use of quantitative ingredient declarations on food labels. All wholegrain foods were considered irrespective of the amount of whole grain they contained.Overall, only 25% of children and 19% of adolescents were wholegrain consumers. Mean daily intakes in the total sample were 2.3g/d (SD 5.8 g/d) in children and 1.7 g/d (SD 4.7 g/d) in adolescents and in the consumer's only sample, mean intakes reached 9.1g/d (SD 8.6) and 9.2g/d (SD 7.1g/d) respectively. Wheat was the main grain source of whole grain while ready to eat breakfast cereals and hot cereals were the main food contributors. Less than 3% of the children and adolescents reached the US quantitative whole grain recommendation of 48 g/day.Whole grain is consumed by only a minority of Malaysian children and adolescents and even among consumers, intakes are well below recommendations. Efforts are needed to firstly understand the barriers to whole grain consumption among Malaysian children in order to design effective health promotion initiatives to promote an increase in whole grain consumption
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