Model Management Systems: Proposed Model Representations and Future Designs

The availability of microcomputers, modeling langauges and general purpose spreadsheets has resulted in an increase in the use of models for decision making within organizatons. Decision makers with microcomputers on their desks and spreadsheet and modeling software can create models rapidly. Problems with model redundancy, consistency, integrity and security have prompted an increased interest in the design of model management systems (MMS). Several model management designs have been discussed in the literature. Different model representation techniques have been proposed. These include formal logic, semantic inheritance networks, frames, and relational representations. The approaches to model management are evaluated in respect to their model manipulation and model storage functions. A framework for the design of MMS is proposed based on the system design objectives and the system domain complexity. Advantages and disadvantages of each model representation method are identified. Application domains for the classifications are proposed which focus on the strengths and weaknesses of the model representation for supporting model storage and model manipulation functions. An example of the design of a MMS using the classification is presented

Are Urban Parents Familiar With Ways to be Involved in a Child\u27s Education?

The purpose of the research was to ascertain if parents of students who attend school in an urban setting could identify ways to be involved in a child\u27s education at home and at school. The research was conducted over an eight week period. The subjects of the research were adults from various parts of the country. However, it should be noted that out of the twenty urban parents that took part in the research, the vast majority of them resided in the Rochester, New York area. The research was collected through interviewing the participants. The interviews were conducted over the phone or in person, depending upon the wishes of the participant. The results of the research collected show that most urban parents know how to be involved in a child\u27s education at home and at school. However, it is important to point out that although most parents were only able to identify one to three ways to be involved in a child\u27s education at home or at school. One of the suggestions for implications for future research include establishing a sound criterion that would gauge not only the quantity of answers given by parents, but also the quality of answers. Another suggestion would be to obtain a more random sample of urban parents, perhaps one that doesn\u27t have a large percentage of its parents in a centralized location in and around the city of Rochester

Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis

BackgroundHistologically assessed liver fibrosis stage has prognostic significance in patients with non-alcoholic fatty liver disease (NAFLD) and is accepted as a surrogate endpoint in clinical trials for non-cirrhotic NAFLD. Our aim was to compare the prognostic performance of non-invasive tests with liver histology in patients with NAFLD.MethodsThis was an individual participant data meta-analysis of the prognostic performance of histologically assessed fibrosis stage (F0–4), liver stiffness measured by vibration-controlled transient elastography (LSM-VCTE), fibrosis-4 index (FIB-4), and NAFLD fibrosis score (NFS) in patients with NAFLD. The literature was searched for a previously published systematic review on the diagnostic accuracy of imaging and simple non-invasive tests and updated to Jan 12, 2022 for this study. Studies were identified through PubMed/MEDLINE, EMBASE, and CENTRAL, and authors were contacted for individual participant data, including outcome data, with a minimum of 12 months of follow-up. The primary outcome was a composite endpoint of all-cause mortality, hepatocellular carcinoma, liver transplantation, or cirrhosis complications (ie, ascites, variceal bleeding, hepatic encephalopathy, or progression to a MELD score ≥15). We calculated aggregated survival curves for trichotomised groups and compared them using stratified log-rank tests (histology: F0–2 vs F3 vs F4; LSM: 2·67; NFS: 0·676), calculated areas under the time-dependent receiver operating characteristic curves (tAUC), and performed Cox proportional-hazards regression to adjust for confounding. This study was registered with PROSPERO, CRD42022312226.FindingsOf 65 eligible studies, we included data on 2518 patients with biopsy-proven NAFLD from 25 studies (1126 [44·7%] were female, median age was 54 years [IQR 44–63), and 1161 [46·1%] had type 2 diabetes). After a median follow-up of 57 months [IQR 33–91], the composite endpoint was observed in 145 (5·8%) patients. Stratified log-rank tests showed significant differences between the trichotomised patient groups (p<0·0001 for all comparisons). The tAUC at 5 years were 0·72 (95% CI 0·62–0·81) for histology, 0·76 (0·70–0·83) for LSM-VCTE, 0·74 (0·64–0·82) for FIB-4, and 0·70 (0·63–0·80) for NFS. All index tests were significant predictors of the primary outcome after adjustment for confounders in the Cox regression.InterpretationSimple non-invasive tests performed as well as histologically assessed fibrosis in predicting clinical outcomes in patients with NAFLD and could be considered as alternatives to liver biopsy in some cases

Business fundamentals. : V 4. : Information technology for managers.

V. 4.; vi, 132 p.; 28 cm

Corporate Information Strategy and Management : Text and Cases

Bostonx, 726 p.; illus.; 25 cm

Corporate information systems management : text and cases, 4th ed./ Applegate

xvii, 796 hal. : tab. ; 23 cm