325 research outputs found

    Susceptibility weighted imaging in intracranial hemorrhage:not all bleeds are black

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    To correctly recognize intracranial hemorrhage (ICH) and differentiate it from other lesions, knowledge of the imaging characteristics of an ICH on Susceptibility Weighted Imaging (SWI) is essential. It is a common misconception that blood is always black on SWI, and it is important to realize that hemorrhage has a variable appearance in different stages on SWI. Furthermore, the presence of a low signal on SWI does not equal the presence of blood products. In this review the appearance of ICH on SWI during all its stages and common other causes of a low signal on SWI are further discussed and illustrated.</p

    Outcomes of submucosal (T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection

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    AIM: To investigate the outcomes and recurrences of pT1b esophageal adenocarcinoma (EAC) following endoscopic mucosal resection (EMR) and associated treatments. METHODS: Patients undergoing EMR with pathologically confirmed T1b EAC at two academic referral centers were retrospectively identified. Patients were divided into 4 groups based on treatment following EMR: Endoscopic therapy alone (group A), endoscopic therapy with either chemotherapy, radiation or both (group B), surgical resection (group C) or no further treatment/lost to follow-up (< 12 mo) (group D). Pathology specimens were reviewed by a central pathologist. Follow-up data was obtained from the academic centers, primary care physicians and/or referring physicians. Univariate analysis was performed to identify factors predicting recurrence of EAC. RESULTS: Fifty-three patients with T1b EAC underwent EMR, of which 32 (60%) had adequate follow-up ≥ 12 mo (median 34 mo, range 12-103). There were 16 patients in group A, 9 in group B, 7 in group C and 21 in group D. Median follow-up in groups A to C was 34 mo (range 12-103). Recurrent EAC developed overall in 9 patients (28%) including 6 (38%) in group A (median: 21 mo, range: 6-73), 1 (11%) in group B (median: 30 mo, range: 30-30) and 2 (29%) in group C (median 21 mo, range: 7-35. Six of 9 recurrences were local; of the 6 recurrences, 5 were treated with endoscopy alone. No predictors of recurrence of EAC were identified. CONCLUSION: Endoscopic therapy of T1b EAC may be a reasonable strategy for a subset of patients including those either refusing or medically unfit for esophagectomy

    Vergroten zelfvoorzienendheid watervoorziening glastuinbouw : watervraag glastuinbouw Haaglanden : deelrapport A

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    De watervoorziening van de glastuinbouw in Haaglanden staat onder druk door toekomstige ontwikkelingen zoals klimaatverandering (langere perioden van droogte en toename verzilting), veranderingen in het beheer van het hoofdwatersysteem en verschuivingen in de zoet-zout grens (uitvoering kierbesluit en planvorming voor een zout water Volkerak-Zoommeer) en de discussie rondom het infiltreren van brijn in de ondergrond. Dit heeft zowel betrekking op de beschikbaarheid van regenwater als ook van voldoende en geschikt oppervlaktewater

    Eindrapport 20 juni 2014 : deelrapport B: wateraanbod glastuinbouw Haaglanden

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    In de regio Haaglanden is veel glastuinbouw. Op dit moment wordt hemelwater als primaire gietwaterbron gebruikt voor de substraatteelt, wat 88% van het glastuinbouw areaal in deze regio beslaat. Bedrijven zijn verplicht een hemel-waterberging te hebben van minimaal 500 m3/ha. Dit is echter niet genoeg voor de meeste bedrijven. Doordat water tijdens piekbuien onvoldoende kan worden opgevangen, en het meeste water nodig is in een periode met weinig regenval, ontstaat een watertekort. Om het huidige tekort op te lossen wordt een alternatieve bron ingezet als aanvullend gietwater. Een veelbelovende alternatieve gietwaterbron lijkt water van de afvalwaterzui-vering Harnaschpolder. Behalve het inzetten van een alternatieve waterbron, of het vergroten van de bergingscapaciteit, kan ook gezocht worden naar manieren om de watervraag te verminderen

    Importance of Occlusion Site for Thrombectomy Technique in Stroke:Comparison Between Aspiration and Stent Retriever

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    BACKGROUND AND PURPOSE: Thrombectomy with stent retriever and direct aspiration are equally effective in the endovascular treatment of anterior circulation acute ischemic stroke. We report efficacy and safety of initial treatment technique per occlusion segment. METHODS: For this study, we analyzed data from the MR CLEAN Registry, a prospective, observational study in all centers that perform endovascular therapy in the Netherlands. We used ordinal logistic regression analysis to compare clinical and technical results of first line direct aspiration treatment with that of stent retriever thrombectomy stratified for occlusion segment. Primary outcome measure was functional outcome at 3 months. Secondary outcome measures included reperfusion grade expressed as the extended Thrombolysis in Cerebral Infarction score, periprocedural complication risk, time to reperfusion, and mortality. RESULTS: Of the 2282 included patients, 1658 (73%) were initially treated with stent retriever and 624 (27%) with aspiration. Four hundred sixty-two patients had an occlusion of the intracranial part of the carotid artery, 1349 of the proximal middle cerebral artery, and 471 of the distal parts of the middle cerebral artery. There was no difference in functional outcome between aspiration and stent retriever thrombectomy (odds ratio, 1.0 [95% CI, 0.9-1.2]) in any of the occlusion segments (P value for interaction=0.2). Reperfusion rate was higher in the aspiration group (odds ratio, 1.4 [95% CI, 1.1-1.6]) and did not differ between occlusion segments (P value for interaction=0.6). Procedure times were shorter in the aspiration group (minutes 50 versus 65 minutes; P<0.0001). There was no difference in periprocedural complications or mortality. CONCLUSIONS: In unselected patients with anterior circulation infarcts, we observed equal functional outcome of aspiration and stent retriever thrombectomy in all occlusion segments. When aspiration was the first line treatment modality, reperfusion rates were higher and procedure times shorter in all occlusion segments
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