Molecular Functionalization of Carbon Nanotubes and Use as Substrates for Neuronal Growth

A cell and substrate system and nerve regeneration implant are disclosed including a carbon nanotube and a neuron growing on the carbon nanotube. Both unfunctionalized carbon nanotubes and carbon nanotubes functionalized with a neuronal growth promoting agent may be utilized in the invention. A method is also disclosed for promoting neuronal growth

First observations of the X-ray transient EXO 2030+375 with IBIS/ISGRI

We present a first INTEGRAL observation of the 42s transient X-ray pulsar EXO 2030+375 with IBIS/ISGRI. The source was detected during Cyg X-1 observations in December 2002. We analyzed observations during the outburst period from 9 to 21 December 2002 with a total exposure time of ~770 kiloseconds. EXO 2030+375 was almost always detected during single ~30 minute exposures in the 18-45 energy bands. The source light curve shows the characteristic outburst shape observed in this source.Comment: 4 pages, 3 figures (1 in CMYK color), accepted by Astronomy and Astrophysics, INTEGRAL special issue, 200

Serum butyrylcholinesterase in type 2 diabetes mellitus: a biochemical and bioinformatics approach

BACKGROUND: Butyrylcholinesterase is an enzyme that may serve as a marker of metabolic syndrome. We (a) measured its level in persons with diabetes mellitus, (b) constructed a family tree of the enzyme using nucleotide sequences downloaded from NCBI. Butyrylcholinesterase was estimated colorimetrically using a commercially available kit (Randox Lab, UK). Phylogenetic trees were constructed by distance method (Fitch and Margoliash method) and by maximum parsimony method. RESULTS: There was a negative correlation between serum total cholesterol and butyrylcholinesterase (-0.407; p < 0.05) and between serum LDL cholesterol and butyrylcholinesterase (-0.435; p < 0.05). There was no statistically significant correlation among the other biochemical parameters. In the evolutionary tree construction both methods gave similar trees, except for an inversion in the position of Sus scrofa (M62778) and Oryctolagus cuniculus (M62779) between Fitch and Margoliash, and maximum parsimony methods. CONCLUSION: The level of butyrylcholinesterase enzyme was inversely related to serum cholesterol; dendrogram showed that the structures from evolutionarily close species were placed near each other

Estimating Be Star Disk Radii using H-alpha Emission Equivalent Widths

We present numerical models of the circumstellar disks of Be stars, and we describe the resulting synthetic H-alpha emission lines and maps of the wavelength-integrated emission flux projected onto the sky. We demonstrate that there are monotonic relationships between the emission line equivalent width and the ratio of the angular half-width at half maximum of the projected disk major axis to the radius of the star. These relationships depend mainly upon the temperatures of the disk and star, the inclination of the disk normal to the line of sight, and the adopted outer boundary for the disk radius. We show that the predicted H-alpha disk radii are consistent with those observed directly through long baseline interferometry of nearby Be stars (especially once allowance is made for disk truncation in binaries and for dilution of the observed H-alpha equivalent width by continuum disk flux in the V-band).Comment: 12 pages, 2 figures, ApJL in pres

4U2206+54 - an Unusual High Mass X-ray Binary with a 9.6 Day Orbital Period but No Strong Pulsations

Rossi X-ray Timing Explorer All-Sky Monitor observations of the X-ray source 4U2206+54, previously proposed to be a Be star system, show the X-ray flux to be modulated with a period of approximately 9.6 days. If the modulation is due to orbital variability then this would be one of the shortest orbital periods known for a Be star X-ray source. However, the X-ray luminosity is relatively modest whereas a high luminosity would be predicted if the system contains a neutron star accreting from the denser inner regions of a Be star envelope. Although a 392s pulse period was previously reported from EXOSAT observations, a reexamination of the EXOSAT light curves does not show this or any other periodicity. An analysis of archival RXTE Proportional Counter Array observations also fails to show any X-ray pulsations. We consider possible models that may explain the properties of this source including a neutron star with accretion halted at the magnetosphere and an accreting white dwarf.Comment: Accepted for publication in the Astrophysical Journa

Crustal Heating and Quiescent Emission from Transiently Accreting Neutron Stars

Nuclear reactions occurring deep in the crust of a transiently accreting neutron star efficiently maintain the core at a temperature >5e7 K. When accretion halts, the envelope relaxes to a thermal equilibrium set by the flux from the hot core, as if the neutron star were newly born. For the time-averaged accretion rates typical of low-mass X-ray transients, standard neutrino cooling is unimportant and the core thermally re-radiates the deposited heat. The resulting luminosity has the same magnitude as that observed from several transient neutron stars in quiescence. Confirmation of this mechanism would strongly constrain rapid neutrino cooling mechanisms for neutron stars. Thermal emission had previously been dismissed as a predominant source of quiescent emission since blackbody spectral fits implied an emitting area much smaller than a neutron star's surface. However, as with thermal emission from radio pulsars, fits with realistic emergent spectra will imply a substantially larger emitting area. Other emission mechanisms, such as accretion or a pulsar shock, can also operate in quiescence and generate intensity and spectral variations over short timescales. Indeed, quiescent accretion may produce gravitationally redshifted metal photoionization edges in the quiescent spectra (detectable with AXAF and XMM). We discuss past observations of Aql~X-1 and note that the low luminosity X-ray sources in globular clusters and the Be star/X-ray transients are excellent candidates for future study.Comment: 5 pages, 2 ps figures, uses AASTEX macros. To appear in ApJ letters, 10 September 1998. Revised to conform with journal; minor numerical correction

Quasi-periodic flares in EXO 2030+375 observed with INTEGRAL

Context: Episodic flaring activity is a common feature of X-ray pulsars in HMXBs. In some Be/X-ray binaries flares were observed in quiescence or prior to outbursts. EXO 2030+375 is a Be/X-ray binary showing "normal" outbursts almost every ~46 days, near periastron passage of the orbital revolution. Some of these outbursts were occasionally monitored with the INTEGRAL observatory. Aims: The INTEGRAL data revealed strong quasi-periodic flaring activity during the rising part of one of the system's outburst. Such activity has previously been observed in EXO 2030+375 only once, in 1985 with EXOSAT. (Some indications of single flares have also been observed with other satellites.) Methods: We present the analysis of the flaring behavior of the source based on INTEGRAL data and compare it with the flares observed in EXO 2030+375 in 1985. Results: Based on the observational properties of the flares, we argue that the instability at the inner edge of the accretion disk is the most probable cause of the flaring activity.Comment: Accepted for publication in A&A Lette

Optical pulsations in the cataclysmic binary 3A 0729+103

Fast photometric observations of the newly discovered cataclysmic variable 3A 0729+103 are reported. Regular optical pulsations, with an average semiamplitude of ~0.15 mag in B-band and having a period in agreement with that reported by McHardy et al. (1982) are clearly detected in the light curve of the star. The optical pulse has a sinusoidal shape. Flares with a maximum amplitude of ~0.43 mag have also been observed. There is also suggestion of flickering on time scales of ≧10s. It is suggested that 3A 0729+103 is similar in characteristics to H 2252-035 class of cataclysmic binaries containing rapidly rotating white dwarfs. Interpretation of the period of optical pulse as the beat period leads to prediction of X-ray pulse period to be about 847s for prograde rotation and 991s for retrograde rotation of the white dwarf compared to the reported ~900-1000s period. Alternative interpretation of the observed optical pulse being due to directly beamed radiation from the vicinity of the pole of the white dwarf is also considered

Photometric Observations of Three High Mass X-Ray Binaries and a Search for Variations Induced by Orbital Motion

We searched for long period variation in V-band, Ic-band and RXTE X-ray light curves of the High Mass X-ray Binaries (HMXBs) LS 1698 / RX J1037.5-5647, HD 110432 / 1H 1249-637 and HD 161103 / RX J1744.7-2713 in an attempt to discover orbitally induced variation. Data were obtained primarily from the ASAS database and were supplemented by shorter term observations made with the 24- and 40-inch ANU telescopes and one of the robotic PROMPT telescopes. Fourier periodograms suggested the existence of long period variation in the V-band light curves of all three HMXBs, however folding the data at those periods did not reveal convincing periodic variation. At this point we cannot rule out the existence of long term V-band variation for these three sources and hints of longer term variation may be seen in the higher precision PROMPT data. Long term V-band observations, on the order of several years, taken at a frequency of at least once per week and with a precision of 0.01 mag, therefore still have a chance of revealing long term variation in these three HMXBs.Comment: Accepted, RAA, May, 201