Primary Gastrointestinal Kaposi’s Sarcoma in a Patient with Human Immunodeficiency Virus

Gastrointestinal bleeding in HIV patients secondary to coinfection by HHV8 and development of Kaposi’s sarcoma (KS) is a rare complication even if no skin lesions are detected on physical examination. This article indicates which patients might develop this type of clinical sign and also tries to recall that absence of skin lesions never rules out the presence of KS, especially if gastrointestinal involvement is documented. Gastrointestinal bleeding in terms of hematemesis has rarely been reported in the literature. We review some important clinical findings, diagnosis, and treatment approach. We present the case of an HIV patient who presented to the emergency department with hematemesis and gastrointestinal signs of KS on upper gastrointestinal endoscopy without any dermatological involvement

Deficiencia congénita del factor V

Blood coagulation factor V (FV) plays a pivotal role in blood coagulation. It is found in both plasma and in platelets and has a profound impact on thrombin generation. Deficiency of this clotting factor due to inherited or acquired conditions results in a broad spectrum of bleeding symptoms. ranging from mucocutaneous bleeding to central nervous system bleeding. We present a case of a 33-year-old woman with abnormal uterine bleeding for several years, not improvement with the management in previous consultations, concluding after several tests a congenital Leiden V factor deficiency.El factor V de la coagulación es encontrado en el plasma y en las plaquetas y tiene un profundo impacto sobre la generación de la trombina. La deficiencia de este factor puede ser congénita o adquirida y se caracteriza por un amplio espectro de signos, que van desde sangrado mucocutáneo hasta compromiso del sistema nervioso central. A continuación se presenta el caso de una paciente de 33 años de edad con hemorragia uterina anormal de varios años de evolución, sin evidenciar mejoría en el manejo instaurado en consultas previas, realizándose paraclínicos que concluyen deficiencia congénita del factor V