Partial Synchronization on Complex Networks

Network topology plays an important role in governing the collective dynamics. Partial synchronization (PaS) on regular networks with a few non-local links is explored. Different PaS patterns out of the symmetry breaking are observed for different ways of non-local couplings. The criterion for the emergence of PaS is studied. The emergence of PaS is related to the loss of degeneration in Lyapunov exponent spectrum. Theoretical and numerical analysis indicate that non-local coupling may drastically change the dynamical feature of the network, emphasizing the important topological dependence of collective dynamics on complex networks.Comment: 4 pages, 4 figure

Synchronization of groups of coupled oscillators with sparse connections

Synchronization of groups of coupled oscillators with sparse connections are explored. It is found that different topologies of intergroup couplings may lead to different synchronizability. In the strong-coupling limit, an analytical treatment and criterion is proposed to judge the synchronization between communities of oscillators, and an optimal connection scheme for the group synchronization is given. By varying the intergroup and intragroup coupling strengths, different synchronous phases, i.e., the unsynchronized state, intragroup synchronization, intergroup synchronization, and global synchronization are revealed. The present discussions and results can be applied to study the pattern formation and synchronization of coupled spatiotemporal systems

Characterization of the HIV-1 integrase chromatin- and LEDGF/p75-binding abilities by mutagenic analysis within the catalytic core domain of integrase

<p>Abstract</p> <p>Background</p> <p>During the early stage of HIV-1 replication, integrase (IN) plays important roles at several steps, including reverse transcription, viral DNA nuclear import, targeting viral DNA to host chromatin and integration. Previous studies have demonstrated that HIV-1 IN interacts with a cellular Lens epithelium-derived growth factor (LEDGF/p75) and that this viral/cellular interaction plays an important role for tethering HIV-1 preintegration complexes (PICs) to transcriptionally active units of host chromatin. Meanwhile, other studies have revealed that the efficient knockdown and/or knockout of LEDGF/p75 could not abolish HIV infection, suggesting a LEDGF/p75-independent action of IN for viral DNA chromatin targeting and integration, even though the underlying mechanism(s) is not fully understood.</p> <p>Results</p> <p>In this study, we performed site-directed mutagenic analysis at the C-terminal region of the IN catalytic core domain responsible for IN/chromatin binding and IN/LEDGF/p75 interaction. The results showed that the IN mutations H171A, L172A and EH170,1AA, located in the loop region ₁₇₀EHLK₁₇₃between the α4 and α5 helices of IN, severely impaired the interaction with LEDGF/p75 but were still able to bind chromatin. In addition, our combined knockdown approach for LEDGF/p75 also failed to dissociate IN from chromatin. This suggests that IN has a LEDGF/p75-independent determinant for host chromatin binding. Furthermore, a single-round HIV-1 replication assay showed that the viruses harboring IN mutants capable of LEDGF/p75-independent chromatin binding still sustained a low level of infection, while the chromatin-binding defective mutant was non-infectious.</p> <p>Conclusions</p> <p>All of these data indicate that, even though the presence of LEDGF/p75 is important for a productive HIV-1 replication, IN has the ability to bind chromatin in a LEDGF/p75-independent manner and sustains a low level of HIV-1 infection. Hence, it is interesting to define the mechanism(s) underlying IN-mediated LEDGF/p75-independent chromatin targeting, and further studies in this regard will help for a better understanding of the molecular mechanism of chromatin targeting by IN during HIV-1 infection.</p

Enhanced hydrogen sensing properties of graphene by introducing a mono-atom-vacancy

To facilitate the dissociative adsorption of H2 molecules on pristine graphene, the addition of a mono-atom-vacancy to graphene is proposed. This leads to reduction of the dissociative energy barrier for a H2 molecule on graphene from 3.097 to 0.805 eV for the first H2 and 0.869 eV for the second, according to first principles calculations. As a result, two H2 molecules can be easily dissociatively adsorbed on this defected graphene at room temperature. The electronic structure and conductivity of the graphene change significantly after H2 adsorption. In addition, the related dissociative adsorption phase diagrams under different temperatures and partial pressures show that this dissociative adsorption at room temperature is very sensitive (10-35 mol L -1). Therefore, this defected graphene is promising for ultra-sensitive room temperature hydrogen sensing. © 2013 the Owner Societies

Transitions To the Long-Resident State in coupled chaotic oscillators

The behaviors of coupled chaotic oscillators before complete synchronization were investigated. We report three phenomena: (1) The emergence of long-time residence of trajectories besides one of the saddle foci; (2) The tendency that orbits of the two oscillators get close becomes faster with increasing the coupling strength; (3) The diffusion of two oscillator's phase difference is first enhanced and then suppressed. There are exact correspondences among these phenomena. The mechanism of these correspondences is explored. These phenomena uncover the route to synchronization of coupled chaotic oscillators.Comment: 3 pages, 5 figure