282 research outputs found

    Effect of prosocial public health messages for population behaviour change in relation to respiratory infections: a systematic review protocol.

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    INTRODUCTION: The COVID-19 pandemic represents a major societal challenge that requires large-scale behaviour change, widespread collective action and cooperation to reduce viral transmission. Existing literature indicates that several messaging approaches may be effective, including emphasising the benefits to the recipient, aligning with the recipient's moral values and focusing on protecting others. Current research suggests that prosocial public health messages that highlight behaviours linked to societal benefits (eg, protecting 'each other'), rather than focusing on behaviours that protect oneself (eg, protecting 'yourself'), may be a more effective method for communicating strategies related to infectious disease. To investigate this we will conduct a systematic review that will identify what messages and behaviour change techniques have the potential to optimise the effect on population behaviour in relation to reducing transmission of respiratory infections. METHODS AND ANALYSIS: A systematic literature search of published and unpublished studies (including grey literature) in electronic databases will be conducted to identify those that meet our inclusion criteria. The search will be run in four electronic databases: MEDLINE, EMBASE, PsycINFO and Scopus. We will also conduct supplementary searches in databases of 'grey' literature such as PsycEXTRA, Social Science Research Network and OSF PREPRINTS, and use the Google Scholar search engine. A systematic approach to searching, screening, reviewing and data extraction will be applied based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Titles, abstracts and full texts for eligibility will be examined independently by researchers. The quality of the included studies will be assessed using the Cochrane Risk of Bias Tool and the Risk of Bias in Non-randomized Studies-of Interventions tool. Disagreements will be resolved by a consensus procedure. ETHICS AND DISSEMINATION: This protocol has been registered with PROSPERO. No ethical approval is required, as there will be no collection of primary data. The synthesised findings will be disseminated through peer-reviewed publication. PROSPERO REGISTRATION NUMBER: CRD42020198874

    Στιγμιαία τιμή της τάσης έναρξης και της τάσης περαίωσης των μερικών εκκενώσεων στο συνδυασμό "Pertimax-λάδι μετασχηματιστών" υπό κρουστικές τάσεις ± 1,2/100μs εντός ανομοιογενούς πεδίου

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    97 σ.Η διερεύνηση της ηλεκτρονικής συμπεριφοράς, τα φαινόμενα γήρανσης και διάσπασης των ηλεκτρομονωτικών υλικών εντός μονωτικού ελαίου υπό την επίδραση υψηλών τάσεων έχουν αποτελέσει αντικείμενο μελέτης εξαιτίας της ευρείας χρήσης τους στη βιομηχανία. Η εργασία αυτή αφορά σε μετρήσεις που έγιναν στον συνδυασμό «Pertimax-λάδι μετασχηματιστών» υπό κρουστική τάση ±1,2/100 μs εντός ανομοιογενούς πεδίου και διαρθρώνεται σε τέσσερα μέρη. Στο πρώτο εισαγωγικό μέρος, η θεωρία του οποίου αναφέρεται κυρίως στο βιβλίο του Καθηγητή Ε.Μ.Π. Περικλή Μπούρκα: “Εφαρμογές Κτιριακών – Βιομηχανικών Μελετών και Εγκαταστάσεων”, περιγράφονται οι βασικές ιδιότητες των βιομηχανικών ηλεκτρομονωτικών υλικών, τα κριτήρια αξιολόγησης τους και οι κατηγορίες διάκρισης των μονωτικών υλικών ανάλογα με τη φυσική τους κατάσταση. Στη συνέχεια, εξετάζονται στα είδη καταπόνησης και τα είδη διάτρησης που αυτά υφίστανται. Τέλος στο ίδιο κεφάλαιο αναπτύσσονται οι δύο βασικές θεωρίες για την ερμηνεία του φαινομένου της γήρανσης και διάσπασης: η μακροσκοπική θεωρία και η κβαντομηχανική θεωρία, οι οποίες αποτελούν και το βασικό εργαλείο επεξεργασίας των μετρήσεων για την εξαγωγή συμπερασμάτων. Στο δεύτερο μέρος γίνεται αναφορά στο σκοπό της παρούσας διπλωματικής εργασίας. Περιγράφεται η διαδικασία που ακολουθήθηκε για την πραγματοποίηση των μετρήσεων και ο καθορισμός των μετρούμενων μεγεθών. Παρατίθενται χρήσιμοι ορισμοί για σημαντικά ηλεκτρικά μεγέθη και μαθηματικές σχέσεις με τις οποίες θα αξιολογήσουμε τα μονωτικά υλικά. Στο τρίτο μέρος παρατίθενται πίνακες που αναφέρονται στα αποτελέσματα των μετρήσεων. Οι πίνακες αυτοί περιλαμβάνουν τόσο τα απευθείας μετρούμενα μεγέθη (επιβαλλόμενη τάση και φορτία έναρξης και περαίωσης), όσο και αυτά που υπολογίσαμε για την αξιολόγηση των υλικών (π.χ. κινητικότητα, ένταση πεδίου, ειδική αγωγιμότητα κα). Οι πίνακες συνοδεύονται από τις γραφικές παραστάσεις των κριτηρίων αξιολόγησης ως προς την επιβαλλόμενη τάση uk και την ένταση του ηλεκτρικού πεδίου Εk. Ακολουθεί, η μαθηματική προσέγγιση των γραφικών παραστάσεων. Έτσι γίνεται αντιληπτή οπτικά και θεωρητικά η μεταξύ τους σχέση και παρατηρούμε την εξέλιξη φαινομένων με την αύξηση της επιβαλλόμενης τάσης ή της πεδιακής έντασης. Η διπλωματική εργασία κλείνει, στο τέταρτο μέρος, με τα συμπεράσματα που προκύπτουν από τις μετρήσεις. Τα συμπεράσματα αυτά απορρέουν από τη μελέτη, την επεξεργασία και παρατήρηση μέσω του θεωρητικών εργαλείων, της στατιστικής ανάλυσης και των γραφικών παραστάσεων των υπολογιζόμενων μεγεθών και των φαινομένων που λαμβάνουν χώρα κατά τη διεξαγωγή της πειραματικής διαδικασίας.The examination of the electronic attribute, the ageing and the degradation of electrical insulation material within insulating oil, has been extensively investigated due to their excessive use in the industrial sector This thesis analyses the results of measurements which have been held in conjunction «Pertimax-oil transformers» applying impulse voltage ± 1,2 / 100 μs in a heterogeneous field. The first introductory part, describes the main properties of industrial electrical insulation materials, their evaluation criteria and their division according to their physical condition. Additionally, this study presents the types of strain and perforation. Finally, in the same chapter, the macroscopic theory and the quantum mechanics theory are presented. The methodology of these two theories is used for the interpretation of the results. The theory of this first part is based on the book “Application of Building – Industrial Research and Installation” by P. Mpourkas, Professor in the National Technical University of Athens. The second part refers to the purpose of this thesis, describes the procedure of the measurements and defines the measured magnitude and the mathematical fractions used for the results. In the third part, the results of the measurements and the calculated magnitude are presented in tables. All these are illustrated in diagrams as a function to the implicated voltage uk and the intensity of the electric field Ek. Moreover, these diagrams are approached by a mathematical perspective Finally, the fourth part is the conclusion of this study. The measurements are analyzed according to the theoretical tools of statistics analysis, the graphs and the phenomena that took place during the experimental procedure. At this point, I would like to thank my supervisor Professor for appointing this thesis to me, and for his invaluable support and contribution during its implementation. This thesis analyses the results of measurements which have been held in conjunction «Pertimax-oil transformers» applying impulse voltage ± 1,2 / 100 ms in a heterogeneous field.Ευαγγελία Π. Αντωνοπούλο

    Tailoring the specificity of the type C feruloyl esterase FoFaeC from Fusarium oxysporum towards methyl sinapate by rational redesign based on small molecule docking simulations

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    The type C feruloyl esterase FoFaeC from Fusarium oxysporum is a newly discovered enzyme with high potential for use in the hydrolysis of lignocellulosic biomass but it shows low activity towards sinapates. In this work, small molecule docking simulations were employed in order to identify important residues for the binding of the four model methyl esters of hydroxycinnamic acids, methyl ferulate/caffeate/sinapate/p-coumarate, to the predicted structure of FoFaeC. Subsequently rational redesign was applied to the enzyme’ active site in order to improve its specificity towards methyl sinapate. A double mutation (F230H/T202V) was considered to provide hydrophobic environment for stabilization of the methoxy substitution on sinapate and a larger binding pocket. Five mutant clones and the wild type were produced in Pichia pastoris and biochemically characterized. All clones showed improved activity, substrate affinity, catalytic efficiency and turnover rate compared to the wild type against methyl sinapate, with clone P13 showing a 5-fold improvement in catalytic efficiency. Although the affinity of all mutant clones was improved against the four model substrates, the catalytic efficiency and turnover rate decreased for the substrates containing a hydroxyl substitution

    Validity of the Working Alliance Inventory Within Child Protection Services

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    The Working Alliance Inventory remains a widely studied measure of quality of therapeutic relationships between the practitioner and client. No prior study has examined the psychometrics and validity of the Working Alliance Inventory–Short (WAI-S) in a sample of families, social workers, and trained observers within child protection services. Surveys were completed by 130 families, social workers concerning 274 cases, and observers following 165 home visits during the first wave of data collected from a randomized controlled trial of child protection services. Confirmatory factor analyses were conducted on three versions of the WAI-S and demonstrated moderate to good model fit. Convergent construct validity was found with other standardized measures. Results support the use of the WAI-S during in child protection services practice and research. Future research into family engagement in child protection social work services should focus on the working relationship

    On the Dirichlet to Neumann Problem for the 1-dimensional Cubic NLS Equation on the half-line

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    This is an author-created, un-copyedited version of an article accepted for publication in Nonlinearity. The publisher is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at http://dx.doi.org/10.1088/0951-7715/28/9/3073Initial-boundary value problems for 1-dimensional `completely integrable' equations can be solved via an extension of the inverse scattering method, which is due to Fokas and his collaborators. A crucial feature of this method is that it requires the values of more boundary data than given for a well-posed problem. In the case of cubic NLS, knowledge of the Dirichet data su ces to make the problem well-posed but the Fokas method also requires knowledge of the values of Neumann data. The study of the Dirichlet to Neumann map is thus necessary before the application of the `Fokas transform'. In this paper, we provide a rigorous study of this map for a large class of decaying Dirichlet data. We show that the Neumann data are also su ciently decaying and that, hence, the Fokas method can be applied
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