37 research outputs found

    The Design of a Real-Scale Steel Moment-Resisting Frame for Pseudo-Dynamic Earthquake Testing

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    Background: Forthe reliable prediction of the non-linear response of structures, severe seismic events have proven to be a challenging task. Although much non-linear analysis software exists, the accuracy of the results depends on the assumptions made in the characterization of the members. Typically, the analytical models are calibrated using experimental observations. With this scope, experimental research remains the most reliable mean for the assessment of the seismic performance of structures, and it is crucial to target the development of new analytical models and design methods. Objective: Quasi-static tests can provide information on the non-linear behaviour of subassemblies, but it is often difficult to relate the imposed force or displacement histories to those that might occur during an earthquake. The pseudo-dynamic method combines an on-line computer simulation with experimental information about the tested structure, providing the application of realistic dynamic response histories. In this paper, the preliminary analysis and the design of a pseudo-dynamic testing facility for the experimental study of a real scale two storeys-two bays steel MRF, with classical and innovative joint details, are shown. Methods: Pushover and Incremental Dynamic Analyses carried out with Seismostruct software estimate the forces and displacements expected at each storey for the selected ground motions. These analyses have been performed by varying the structural detail of the beam-to-column connections. Results / Conclusion: In this paper, the analytical prediction of the performance of two bays-two storeys steel frames equipped with different solutions of beam-to-column joints is focused. Based on the performed analyses, it has been recognized that steel frames with partial strength joints can provide satisfactory performance under severe seismic actions provided that the joints are adequately designed

    Original Article

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    The pancreas taken from the frog (Rana nigromaculata) was fixed in 1% OsO_4 and sliced into ultrathin sections for electron microscopic studies. The following observations were made: 1. A great \u27number of minute granules found in the cytoplasm of a pancreatic cell were called the microsomes, which were divided into two types, the C-microsome and S-microsome. 2. Electron microsopic studies of the ergastoplasm showed that it is composed of the microsome granules and A-substance. The microsomes were seen embedded in the A-substance which was either filamentous or membranous. The membranous structure, which was called the Am-membrane, was seen to form a sac, with a cavity of varying sizes, or to form a lamella. 3. The Am-membrane has close similarity to α-cytomembrane of Sjostrand, except that the latter is rough-surfaced. It was deduced that the Am-membrane, which is smooth-surfaced, might turn into the rough-surfaced α-cytomembrane. 4. There was the Golgi apparatus in the supranuclear region of a pancreatic cell. It consisted of the Golgi membrane, Golgi vacuole and. Golgi vesicle. 5. The mitochondria of a pancreatic cell appeared like long filaments, and some of them were seen to ramify. 6. The membrane of mitochondria, i. e. the limiting membrane, consisted of the Ammembrane. The mitochondria contained a lot of A-substances, as well as the C-microsomes and S-microsomes. When the mitochondria came into being, there appeared inside them chains of granules, which appeared like strips of beads, as the outgrowths of the A-substance and the microsome granules attached to the Am-membrane. They are the so-called cristae mitochondriales. 7. The secretory granules originate in the microsomes. They came into being when the microsomes gradually thickened and grew in size as various substances became adhered to them. Some of the secretory granules were covered with a membrane and appeared like what they have called the intracisternal granule of Palade.It seemed that this was a phenomenon attendant upon the dissolution and liqutefaction of the secretory granule. 8. Comparative studies were made of the ergastoplasm of the pancreatic cells from the frogs in hibernation, the frogs artificially hungered, the frogs which were given food after a certain period of fasting, the frogs to which pilocarpine was given subcutaneously, and the very young, immature frogs. The studies revealed that the ergastoplasm of the pancreatic cells greatly varied in form with the difference in nutritive condition and with different developmental stages of the cell. The change in form and structure occured as a result of transformation of the microsomes and A-substance. The ergastoplasm, even after it has come into being, might easily be inactivated if nutrition is defective. The ergastoplasm is concerned in the secretory mechanism, which is different from the secretory phenomenon of the secretory granules. It would seem that structurally the mitochondria have no direct relation to this mechanism

    HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial

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    Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia

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    HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4+ T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial

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    Measurement of the charge asymmetry in top-quark pair production in the lepton-plus-jets final state in pp collision data at s=8TeV\sqrt{s}=8\,\mathrm TeV{} with the ATLAS detector

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    ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider

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    Measurements of top-quark pair differential cross-sections in the eμe\mu channel in pppp collisions at s=13\sqrt{s} = 13 TeV using the ATLAS detector

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    Search for single production of vector-like quarks decaying into Wb in pp collisions at s=8\sqrt{s} = 8 TeV with the ATLAS detector

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    Measurement of the W boson polarisation in ttˉt\bar{t} events from pp collisions at s\sqrt{s} = 8 TeV in the lepton + jets channel with ATLAS

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