Преклинический атеросклероз: эндотелиальная дисфункция, комплекс интима-медиа, сосудистая жесткость

Preclinical atherosclerosis is an acute problem of contemporary medicine with significant effects on cardiovascular morbidity and mortality. Targeting strategy to tackle atherosclerotic disease at incipient clinical stages is undertaken to achieve a significant reduction in major cardiovascular events and reliance on an early assessment of serum markers of endothelial dysfunction and other noninvasive indicators of asymptomatic atherosclerotic arterial disease, such as the intimae-media thickness and arterial stiffness.Преклинический атеросклероз является острой проблемой современной медицины и обладает значительным влиянием на сердечно- сосудистую заболеваемость и смертность. Ориентация стратегии борьбы с атеросклеротической болезнью на преклинических стадиях нацелена на достижение значительного снижения основных сердечно-сосудистых осложнений и основана на ранней оценке сывороточных маркеров эндотелиальной дисфункции и на других неинвазивных показателях бессимптомного атеросклеротического поражения артерий, таких как толщина комплекса интима-медиа и жесткость сосудистых стенок

Many-Body Superconformal Systems from Hamiltonian Reductions

We propose a new reduction mechanism which allows one to construct n-particle (super)conformal theories with pairwise interaction starting from a composite system involving n(n-1)/2+1 copies of the ordinary (super)conformal mechanics. Applications of the scheme include an N=4 superconformal extension for a complexification of the Calogero model and a D(2,1|\alpha)-invariant n-particle system.Comment: 12 pages, no figures. v2: Title changed. New material and acknowledgements adde

Wiring surface loss of a superconducting transmon qubit

Quantum processors using superconducting qubits suffer from dielectric loss leading to noise and dissipation. Qubits are usually designed as large capacitor pads connected to a non-linear Josephson junction (or SQUID) by a superconducting thin metal wiring. Here, we report on finite-element simulation and experimental results confirming that more than 50% of surface loss in transmon qubits can originated from Josephson junctions wiring and can limit qubit relaxation time. Extracting dielectric loss tangents capacitor pads and wiring based on their participation ratios, we show dominant surface loss of wiring can occur for real qubits designs. Then, we simulate a qubit coupled to a bath of individual TLS defects and show that only a small fraction (~18%) of coupled defects is located within the wiring interfaces, however, their coupling strength is much higher due to stronger electromagnetic field. Finally, we fabricate six tunable floating transmon qubits and experimentally demonstrate up to 20% improvement in qubit quality factor by wiring design optimization.Comment: 17 pages, 8 figure

Octahedral chalcogenide rhenium cluster complexes with imidazole

Reactions of [{Re6Q8}Br6]4−/3− (Q = S, Se) with molten imidazole lead to the formation of two new neutral cluster complexes [{Re6Q8}(imzH)4(imz)2] (imzH = imidazole). The interaction of [{Re6Q8}(imzH)4(imz)2] with hydrohalic acids resulted in cationic complexes [{Re6Q8}(imzH)6]X2 (X = Cl, Br). All compounds were characterised by X-ray single-crystal and powder diffraction analyses, elemental analysis, energy dispersive X-ray and IR spectroscopies. The luminescence of the neutral compounds [{Re6Q8}(imzH)4(imz)2] was also studied

Robust cryogenic matched low-pass coaxial filters for quantum computing applications

Electromagnetic noise is one of the key external factors decreasing superconducting qubits coherence. Matched coaxial filters can prevent microwave and IR photons negative influence on superconducting quantum circuits. Here, we report on design and fabrication route of matched low-pass coaxial filters for noise-sensitive measurements at milliKelvin temperatures. A robust transmission coefficient with designed linear absorption (-1dB/GHz) and ultralow reflection losses less than -20 dB up to 20 GHz is achieved. We present a mathematical model for evaluating and predicting filters transmission parameters depending on their dimensions. It is experimentally approved on two filters prototypes different lengths with compound of Cu powder and Stycast commercial resin demonstrating excellent matching. The presented design and assembly route are universal for various compounds and provide high repeatability of geometrical and microwave characteristics. Finally, we demonstrate three filters with almost equal reflection and transmission characteristics in the range from 0 to 20 GHz, which is quite useful to control multiple channel superconducting quantum circuits.Comment: 5 pages, 4 figure

An X-ray photoelectron spectroscopy study of uranyl-chitosan interaction

An X-ray photoelectron spectroscopy study of uranium sorption by spherically-granulated chitosan in sulphate solutions, as well as the study of the nature of the U(VI) - chitosan interaction was carried out in this work. The X-ray photoelectron spectroscopy analysis showed that the uranyl - chitosan interaction results in the formation of complexes with aminogroup nitrogen, and possibly chitin ring oxygens and free hydroxyl groups in the equatorial plane. Under the UHV in the spectrometer chamber, the uranyl-amin and uranyl-hyroxide bonds were shown to break and tetravalent uranium compounds were shown to form on the sample surface. Hydroxyl groups were shown to evaporate. The calculated DG0 = -1,3 kJ/mol can be an evidence of several concurrent processes, some of which require energy, as well as of the formation of a surface chemical compound

Signatures of High-Intensity Compton Scattering

We review known and discuss new signatures of high-intensity Compton scattering assuming a scenario where a high-power laser is brought into collision with an electron beam. At high intensities one expects to see a substantial red-shift of the usual kinematic Compton edge of the photon spectrum caused by the large, intensity dependent, effective mass of the electrons within the laser beam. Emission rates acquire their global maximum at this edge while neighbouring smaller peaks signal higher harmonics. In addition, we find that the notion of the centre-of-mass frame for a given harmonic becomes intensity dependent. Tuning the intensity then effectively amounts to changing the frame of reference, going continuously from inverse to ordinary Compton scattering with the centre-of-mass kinematics defining the transition point between the two.Comment: 25 pages, 16 .eps figure

Counting Statistics of an Adiabatic Pump

We consider quantum statistics of charge transmitted through a mesoscopic device in the adiabatic pumping process. A general formula for the distribution function of the transmitted charge in terms of the time-dependent S-matrix is obtained. It is applied to a few simple examples of the pumping cycles. We identify coherent pumping strategies which lead to the binomial charge distribution and minimize the fluctuations of the pumped current. Conditions for the ideal noiseless quantized pump are discussed.Comment: 4 page

An X-ray photoelectron spectroscopy study of the products of the interaction of gaseous IrF6 with fine UO2F2

Nuclear fuel reprocessing by fluorination, a dry method of regeneration of spent nuclear fuel, uses UO2F2 for the separation of plutonium from gaseous mixtures. Since plutonium requires special treatment, IrF6 was used as a thermodynamic model of PuF6. The model reaction of the interaction of gaseous IrF6 with fine UO2F2 in the sorption column revealed a change of color of the sorption column contents from pale-yellow to gray and black, indicating the formation of products of such an interaction. The X-ray photoelectron spectroscopy study showed that the interaction of gaseous IrF6 with fine UO2F2 at 125 °C results in the formation of stable iridium compounds where the iridium oxidation state is close to Ir3+. The dependence of the elemental compositions of the layers in the sorption column on the penetration depth of IrF6 was established

Conformal mechanics inspired by extremal black holes in d=4

A canonical transformation which relates the model of a massive relativistic particle moving near the horizon of an extremal black hole in four dimensions and the conventional conformal mechanics is constructed in two different ways. The first approach makes use of the action-angle variables in the angular sector. The second scheme relies upon integrability of the system in the sense of Liouville.Comment: V2: presentation improved, new material and references added; the version to appear in JHE