Unrolled primal-dual networks for lensless cameras

Conventional models for lensless imaging assume that each measurement results from convolving a given scene with a single experimentally measured point-spread function. These models fail to simulate lensless cameras truthfully, as these models do not account for optical aberrations or scenes with depth variations. Our work shows that learning a supervised primal-dual reconstruction method results in image quality matching state of the art in the literature without demanding a large network capacity. We show that embedding learnable forward and adjoint models improves the reconstruction quality of lensless images (+5dB PSNR) compared to works that assume a fixed point-spread function

The Impact of regulatory capital regulation on balance sheet structure, intermediation cost and growth

URL des Documents de travail : http://ces.univ-paris1.fr/cesdp/cesdp2016.htmlDocuments de travail du Centre d'Economie de la Sorbonne 2016.61 - ISSN : 1955-611XAs Europe is subject to a protracted recession, it should be asked whether the reform of the financial sector is not costly in terms of potential growth. Our analysis shows that the negative effect of the Basel III package excepted by the pre-QE studies are almost annihilated today. The recession must then have other causes: falling corporate lending volumes resulted from falling demand in the aftermath of the financial crisis, but this is longer the case. The EU is trying to incentivize corporate lending, via forward guidance as well as ‘supporting factor’ cutting down the Basel capital requirements. The macroeconomic theorists are trying to account for future success of monetary policy around zero nominal interest rate via the risk-taking channel. All these clever initiatives failed to deliver. As a consequence, we might infer that banks are simply not taking any risks: rather than appealing to risk aversion, we would like to argue that the banks seem especially embarrassed by future regulatory developments, which appear remote and uncertain. The binding constraint for corporate lending and growth in the EU is then plausibly a combination of banks' expectations of future regulation and strong uncertainty aversion. While we offer some mitigation prospects, we hope that the theoretical developments of the recent years will quickly yield both theoretical advances and practical results.Malgré les assouplissements récents de la règlementation bancaire afin de permettre une reprise des prêts aux entreprises, il semble que le paquet Bâle III ait un effet néfaste sur la croissance. Le texte s'interroge sur la contrainte active parmi l'ensemble des nouvelles règles. Il semblerait que les banques soient devenues très averses à l'incertitude, en particulier à l'incertitude sur l'évolution des règles qui leurs sont imposées. En conséquence nous proposons de modifier la nature des provisions en capital et le nombre de régulateurs ayant un pouvoir de décision sur le niveau des capitaux

Practical realisation and elimination of an ECC-related software bug attack

We analyse and exploit implementation features in OpenSSL version 0.9.8g which permit an attack against ECDH-based functionality. The attack, although more general, can recover the entire (static) private key from an associated SSL server via $633$ adaptive queries when the NIST curve P-256 is used. One can view it as a software-oriented analogue of the bug attack concept due to Biham et al. and, consequently, as the first bug attack to be successfully applied against a real-world system. In addition to the attack and a posteriori countermeasures, we show that formal verification, while rarely used at present, is a viable means of detecting the features which the attack hinges on. Based on the security implications of the attack and the extra justification posed by the possibility of intentionally incorrect implementations in collaborative software development, we conclude that applying and extending the coverage of formal verification to augment existing test strategies for OpenSSL-like software should be deemed a worthwhile, long-term challenge.This work has been supported in part by EPSRC via grant EP/H001689/1 and by project SMART, funded by ENIAC Joint Undertaking (GA 120224)

The change in the activity of biochemical inflammation markers of oral liquid at pain dysfunction of tmj and their correction with inhibitors of cog-2

Проблема диагностики и лечения пациентов с зубочелюстными аномалиями, осложненными заболеваниями височнонижнечелюстного сустава, в настоящее время весьма актуальна. Это связано с отсутствием целенаправленной комплексной тактики лечения данной патологии. Проведенное биохимическое исследование ротовой жидкости пациентов с болевой дисфункцией височнонижнечелюстного сустава продемонстрировало способность мовалиса эффективно снижать уровень основных маркеров воспаления в полости рта. Полученные результаты подтверждают высокую противовоспалительную эффективность "Мовалиса" ("Мелоксикама"), связанную с ингибированием циклооксигеназы-2 и выработки медиаторов воспаления простагландинов.Проблема діагностики і лікування пацієнтів із зубощелепними аномаліями, ускладненими захворюваннями скроневонижньощелепного суглобу, в даний час вельми актуальна. Це пов'язано з відсутністю цілеспрямованої комплексної тактики лікування даної патології. Проведене біохімічне дослідження ротової рідини пацієнтів з больовою дисфункцією скронево-нижньощелепного суглобу продемонструвало здатність мовалісу ефективно знижувати рівень основних маркерів запалення в порожнині рота. Отримані результати підтверджують високу протизапальну ефективність "Мовалісу" ("Мелоксикама"), пов'язану з інгібірованням циклооксигенази-2 і виробленням медіаторів запалення простагландинів.The problem of diagnostics and treatment of the patients with dentoalveolar anomalies, complicated with the diseases of temporomandibular joint, is very topical at present. This fact is connected to the absence of task-specific complex tactics of the treatment of the given pathology. According to the data of WHO during 2008, the frequency of the diseases of TMJ in patients of 35-45 years old is more than 75 %, and the prevalence is from 20 to 80 %. Dysfunction of TMJ is found in 80 % of the pathology of joint in whole

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

Objectives:We utilized the database of the Defining Antibiotic Levels in Intensive care unit patients (DALI) study to statistically compare the pharmacokinetic/pharmacodynamic and clinical outcomes between prolonged-infusion and intermittent-bolus dosing of piperacillin/tazobactam and meropenem in critically ill patients using inclusion criteria similar to those used in previous prospective studies.Methods: This was a post hoc analysis of a prospective, multicentre pharmacokinetic point-prevalence study (DALI), which recruited a large cohort of critically ill patients from 68 ICUs across 10 countries.Results: Of the 211 patients receiving piperacillin/tazobactam and meropenem in the DALI study, 182 met inclusion criteria. Overall, 89.0% (162/182) of patients achieved the most conservative target of 50% fT(> MIC) (time over which unbound or free drug concentration remains above the MIC). Decreasing creatinine clearance and the use of prolonged infusion significantly increased the PTA for most pharmacokinetic/pharmacodynamic targets. In the subgroup of patients who had respiratory infection, patients receiving beta-lactams via prolonged infusion demonstrated significantly better 30 day survival when compared with intermittent-bolus patients [86.2% (25/29) versus 56.7% (17/30); P=0.012]. Additionally, in patients with a SOFA score of >= 9, administration by prolonged infusion compared with intermittent-bolus dosing demonstrated significantly better clinical cure [73.3% (11/15) versus 35.0% (7/20); P=0.035] and survival rates [73.3% (11/15) versus 25.0% (5/20); P=0.025].Conclusions: Analysis of this large dataset has provided additional data on the niche benefits of administration of piperacillin/tazobactam and meropenem by prolonged infusion in critically ill patients, particularly for patients with respiratory infections

SARS-CoV-2 seroprevalence and implications for population immunity: Evidence from two Health and Demographic Surveillance System sites in Kenya, February-December 2022.

BACKGROUND: We sought to estimate SARS-CoV-2 antibody seroprevalence within representative samples of the Kenyan population during the third year of the COVID-19 pandemic and the second year of COVID-19 vaccine use. METHODS: We conducted cross-sectional serosurveys among randomly selected, age-stratified samples of Health and Demographic Surveillance System (HDSS) residents in Kilifi and Nairobi. Anti-spike (anti-S) immunoglobulin G (IgG) serostatus was measured using a validated in-house ELISA and antibody concentrations estimated with reference to the WHO International Standard for anti-SARS-CoV-2 immunoglobulin. RESULTS: HDSS residents were sampled in February-June 2022 (Kilifi HDSS N = 852; Nairobi Urban HDSS N = 851) and in August-December 2022 (N = 850 for both sites). Population-weighted coverage for ≥1 doses of COVID-19 vaccine were 11.1% (9.1-13.2%) among Kilifi HDSS residents by November 2022 and 34.2% (30.7-37.6%) among Nairobi Urban HDSS residents by December 2022. Population-weighted anti-S IgG seroprevalence among Kilifi HDSS residents increased from 69.1% (65.8-72.3%) by May 2022 to 77.4% (74.4-80.2%) by November 2022. Within the Nairobi Urban HDSS, seroprevalence by June 2022 was 88.5% (86.1-90.6%), comparable with seroprevalence by December 2022 (92.2%; 90.2-93.9%). For both surveys, seroprevalence was significantly lower among Kilifi HDSS residents than among Nairobi Urban HDSS residents, as were antibody concentrations (p < 0.001). CONCLUSION: More than 70% of Kilifi residents and 90% of Nairobi residents were seropositive for anti-S IgG by the end of 2022. There is a potential immunity gap in rural Kenya; implementation of interventions to improve COVID-19 vaccine uptake among sub-groups at increased risk of severe COVID-19 in rural settings is recommended

Lawson criterion for ignition exceeded in an inertial fusion experiment

For more than half a century, researchers around the world have been engaged in attempts to achieve fusion ignition as a proof of principle of various fusion concepts. Following the Lawson criterion, an ignited plasma is one where the fusion heating power is high enough to overcome all the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop with rapidly increasing temperature. In inertially confined fusion, ignition is a state where the fusion plasma can begin "burn propagation" into surrounding cold fuel, enabling the possibility of high energy gain. While "scientific breakeven" (i.e., unity target gain) has not yet been achieved (here target gain is 0.72, 1.37 MJ of fusion for 1.92 MJ of laser energy), this Letter reports the first controlled fusion experiment, using laser indirect drive, on the National Ignition Facility to produce capsule gain (here 5.8) and reach ignition by nine different formulations of the Lawson criterion