6,416 research outputs found

    Is There a Difference Between Democrat and Republican States in the Percentage of Male High School Students Who Physically Fight on Campus?

    Get PDF
    School violence is a common occurrence in American high schools. Victims of school violence are more likely than others to become depressed, skip school, and commit suicide. In addition, intimidation, threats, sexual harassment, prejudice, gossip, and ridicule are serious threats to successful education. Overall, about 33% of students are bullied at school by other students, and bullying leads to fights. Because Democrats and Republicans support two different types of social learning environments that will modify the behaviors of residents within their respective jurisdictions, and because public safety is an important social issue, it is important to know if there is a difference between Democrat and Republican jurisdictions and aggressive behaviors of high school students. Therefore, the purpose of this study was to determine if there is a difference between Democrat and Republican states in the percentage of male high school students who physically fight on campus. This study examined electronic second-hand data collected in 2013, 2015, and 2017 by the Centers for Disease Control and Prevention. Data were collected via the Youth Risk Behavior Surveillance System (YRBSS) using a three-stage cluster sample design, which produced a nationally representative sample of students in grades 9-12 who attended public and private schools. The results of the logistic regression for repeated measures indicate that there is no statistically significant relationship between male high school students who physically fight on campus and political party

    The Education of Black Males in a \u27Post-Racial\u27 World

    Get PDF
    The Education of Black Males in a ‘Post-Racial’ World examines the varied structural and discursive contexts of race, masculinities and class that shape the educational and social lives of Black males. The contributing authors take direct aim at the current discourses that construct Black males as disengaged in schooling because of an autonomous Black male culture, and explore how media, social sciences, school curriculum, popular culture and sport can define and constrain the lives of Black males. The chapters also provide alternative methodologies, theories and analyses for making sense of and addressing the complex needs of Black males in schools and in society. By expanding our understanding of how unequal access to productive opportunities and quality resources converge to systemically create disparate experiences and outcomes for African-American males, this volume powerfully illustrates that race still matters in \u27post-racial\u27 America.https://scholarworks.wm.edu/educationbookchapters/1047/thumbnail.jp

    Relating Regularization and Generalization through the Intrinsic Dimension of Activations

    Full text link
    Given a pair of models with similar training set performance, it is natural to assume that the model that possesses simpler internal representations would exhibit better generalization. In this work, we provide empirical evidence for this intuition through an analysis of the intrinsic dimension (ID) of model activations, which can be thought of as the minimal number of factors of variation in the model's representation of the data. First, we show that common regularization techniques uniformly decrease the last-layer ID (LLID) of validation set activations for image classification models and show how this strongly affects generalization performance. We also investigate how excessive regularization decreases a model's ability to extract features from data in earlier layers, leading to a negative effect on validation accuracy even while LLID continues to decrease and training accuracy remains near-perfect. Finally, we examine the LLID over the course of training of models that exhibit grokking. We observe that well after training accuracy saturates, when models ``grok'' and validation accuracy suddenly improves from random to perfect, there is a co-occurent sudden drop in LLID, thus providing more insight into the dynamics of sudden generalization.Comment: NeurIPS 2022 OPT and HITY workshop

    Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFα

    Get PDF
    Activated macrophages secrete an array of proinflammatory cytokines, including tumor necrosis factor-α (TNFα) and interleukin 6 (IL-6), that are temporally secreted for sequential roles in inflammation. We have previously characterized aspects of the intracellular trafficking of membrane-bound TNFα and its delivery to the cell surface at the site of phagocytic cups for secretion (Murray, R.Z., J.G. Kay, D.G. Sangermani, and J.L. Stow. 2005. Science. 310:1492–1495). The trafficking pathway and surface delivery of IL-6, a soluble cytokine, were studied here using approaches such as live cell imaging of fluorescently tagged IL-6 and immunoelectron microscopy. Newly synthesized IL-6 accumulates in the Golgi complex and exits in tubulovesicular carriers either as the sole labeled cargo or together with TNFα, utilizing specific soluble NSF attachment protein receptor (SNARE) proteins to fuse with the recycling endosome. Within recycling endosomes, we demonstrate the compartmentalization of cargo proteins, wherein IL-6 is dynamically segregated from TNFα and from surface recycling transferrin. Thereafter, these cytokines are independently secreted, with TNFα delivered to phagocytic cups but not IL-6. Therefore, the recycling endosome has a central role in orchestrating the differential secretion of cytokines during inflammation

    Effectiveness and cost-effectiveness of a universal parenting skills programme in deprived communities : multicentre randomised controlled trial

    Get PDF
    Objective: To evaluate the effectiveness and cost utility of a universally provided early years parenting programme. Design: Multicentre randomised controlled trial with cost-effectiveness analysis. Setting: Early years centres in four deprived areas of South Wales. Participants: Families with children aged between 2 and 4 years. 286 families were recruited and randomly allocated to the intervention or waiting list control. Intervention: The Family Links Nurturing Programme (FLNP), a 10-week course with weekly 2 h facilitated group sessions. Main outcome measures: Negative and supportive parenting, child and parental well-being and costs assessed before the intervention, following the course (3 months) and at 9 months using standardised measures. Results: There were no significant differences in primary or secondary outcomes between trial arms at 3 or 9 months. With ‘+’ indicating improvement, difference in change in negative parenting score at 9 months was +0.90 (95%CI −1.90 to 3.69); in supportive parenting, +0.17 (95%CI −0.61 to 0.94); and 12 of the 17 secondary outcomes showed a non-significant positive effect in the FLNP arm. Based on changes in parental well-being (SF-12), the cost per quality-adjusted life year (QALY) gained was estimated to be £34 913 (range 21 485–46 578) over 5 years and £18 954 (range 11 664–25 287) over 10 years. Probability of cost per QALY gained below £30 000 was 47% at 5 years and 57% at 10 years. Attendance was low: 34% of intervention families attended no sessions (n=48); only 47% completed the course (n=68). Also, 19% of control families attended a parenting programme before 9-month follow-up. Conclusions: Our trial has not found evidence of clinical or cost utility for the FLNP in a universal setting. However, low levels of exposure and contamination mean that uncertainty remains. Trial registration: The trial is registered with Current Controlled Trials ISRCTN13919732

    Highly polymorphic microsatellites in the North American snakeweed grasshopper, Hesperotettix viridis

    Get PDF
    Microsatellite markers are preferred for fine-scale population genetic studies requiring high resolution. The grasshopper Hesperotettix viridis (Thomas) is an oligophagous species that feeds on composites and often exhibits locally restricted diets. Divergence in host plant use in some localities is seen where co-occurring subpopulations select alternate plant species, as expected with the evolution of host shifts and associated lineage divergence. To characterize the host-associated divergence patterns among populations of H. viridis, we developed markers from two microsatellite-enriched genomic libraries. Here we report the characterization and optimization of seven polymorphic di- and tri-nucleotide microsatellite loci for this species. One hundred and six individuals from 5 populations were tested for polymorphism. The number of alleles varied from 4 to 38 in all the populations. Ho ranged from 0.339 to 0.790. Homozygote excess was observed across loci, perhaps due to inbreeding. This is the first report of microsatellite markers for the subfamily Melanoplinae

    Constraints on the Progenitor of SN 2016gkg From Its Shock-Cooling Light Curve

    Full text link
    SN 2016gkg is a nearby Type IIb supernova discovered shortly after explosion. Like several other Type IIb events with early-time data, SN 2016gkg displays a double-peaked light curve, with the first peak associated with the cooling of a low-mass extended progenitor envelope. We present unprecedented intranight-cadence multi-band photometric coverage of the first light-curve peak of SN 2016gkg obtained from the Las Cumbres Observatory Global Telescope network, the Asteroid Terrestrial-impact Last Alert System, the Swift satellite and various amateur-operated telescopes. Fitting these data to analytical shock-cooling models gives a progenitor radius of ~25-140 solar radii with ~2-30 x 10^-2 solar masses of material in the extended envelope (depending on the model and the assumed host-galaxy extinction). Our radius estimates are broadly consistent with values derived independently (in other works) from HST imaging of the progenitor star. However, the shock-cooling model radii are on the lower end of the values indicated by pre-explosion imaging. Hydrodynamical simulations could refine the progenitor parameters deduced from the shock-cooling emission and test the analytical models.Comment: Accepted by ApJ
    • …
    corecore