Additional file 1: of Laquinimod attenuates inflammation by modulating macrophage functions in traumatic brain injury mouse model

Inflammation-related gene expression changes in microglia. A, Gene expression of inflammatory-related molecules in microglia as measured by MG468 chip. B–C, qPCR validation of iNOS (B) and IL-6 (C) in microglia. We studied 5–7 mice per group from at least three independent experiments. Bars show mean ± s.e.m. (n = 5). (PDF 97 kb

An evaluation of the international Baccalaureate Mathematical Studies course for non-mathematicians

Additional file 4. There were no differences in parasitaemia and mortality between those mice treated with fraction A and untreated mice during P. berghei ANKA infection. (A) Parasitaemia, (B) survival and (C) body weight loss of C57BL/6 mice that received 10 mg/kg of A. blazei fraction A or 30 mg/kg of chloroquine three days before infection, then infected with 105 pRBCs, and treated until 7 dpi. Parasitaemia and body weight values are expressed as mean ± SD of 5 mice per group. Log-rank test and *p < 0.05, **p < 0.01 and ***p < 0.001, ANOVA followed Bonferroni’s test

MOESM6 of Effect of mushroom Agaricus blazei on immune response and development of experimental cerebral malaria

Additional file 6. Fraction C treated mice did not display clinical signs of CM and significant differences in haematrocrit during P. berghei infection. C57BL/6 mice were treated with fraction C of A. blazei or chloroquine three days before infection, then infected with 105 pRBCs, and treated until 7 dpi. (A) clinical signs of cerebral malaria assessed by the RMCBS score and (B) haematocrit assessed on 5th dpi, normalized relative to that of uninfected controls for each mouse group. RMCBS score and haematocrit values were expressed as mean ± SD of 5 mice per group. ***p < 0.001, ANOVA followed Bonferroni’s test

MOESM2 of Effect of mushroom Agaricus blazei on immune response and development of experimental cerebral malaria

Additional file 2. Administration of 800 mg/kg of Agaricus blazei lyophilized extract resulted in significant survival of P. berghei ANKA-infected mice. (A) Parasitaemia and (B) survival of C57BL/6 mice that received 80 mg/kg or 800 mg/kg of A. blazei lyophilized extract or 30 mg/kg of chloroquine three days before infection, then infected with 105 pRBCs, and treated until 7 dpi. Parasitaemia expressed as mean ± SD of 5 mice per group. (A) ANOVA followed Bonferroni’s test was applied and (B) # p<0.001 Log-rank test