Absolute Frequency Atlas from 915 nm to 985 nm based on Laser Absorption Spectroscopy of Iodine

This article reports on laser absorption spectroscopy of iodine gas between 915 nm and 985 nm. This wavelength range is scanned utilizing a narrow linewidth and mode-hop-free tunable diode-laser whose frequency is actively controlled using a calibrated wavelength meter. This allows us to provide an iodine atlas that contains almost 10,000 experimentally observed reference lines with an uncertainty of 50 MHz. For common lines, good agreement is found with a publication by Gerstenkorn et al. [S. Gerstenkorn, P. Luc, Atlas du spectre d'absorption de la molecule d'iode 14800-20000 cm$^{-1}$, Paris: Editions du Centre National de la Recherche Scientifique (CNRS), 1978]. The new rich dataset allows existing models of the iodine molecule to be refined and can serve as a reference for laser frequency calibration and stabilization.Comment: 7 pages, 4 figures, link to online data depositor

SNP information

This file contains information on SNPs

Genotypes_for_209_horses

This file contains genotype information on 54,602 SNPs for 209 horses. The genotypes are from Illumina 50K SNP chip

Information on samples

This file contains information on phenotype, gender, region, age, sire and dam for 209 horses

Additional file 6: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity

Chromosomal distribution, characteristics and enrichment of detected CNVs and CNVRs. Number of CNVs and CNVRs detected per Equus caballus chromosome (ECA), including detection, state, content, mean size (in base pairs), coverage (in base pairs), chromosomal distribution ( = number of CNVs per chromosome total number of CNVs × 100 % $$=\frac{number\kern0.5em of\kern0.5em CNVs\kern0.5em per\kern0.5em chromosome}{total\kern0.5em number\kern0.5em of\kern0.5em CNVs}\times \kern0.5em 100\%$$ ), chromosomal coverage ( CNVR coverage per chromosome length of chromosome × 100 % $$\frac{CNVR\kern0.5em coverage\kern0.5em per\kern0.5em chromosome}{length\kern0.5em of\kern0.5em chromosome}\times 100\%$$ ) and SNP coverage in base pairs ( = length of chromosome number of SNPs per chromosome $$=\frac{length\kern0.5em of\kern0.5em chromosome}{number\kern0.5em of\kern0.5em SNPs\kern0.5em per\kern0.5em chromosome}$$ ). (DOCX 24 kb

Additional file 3: of A nonsense mutation in B3GALNT2 is concordant with hydrocephalus in Friesian horses

Genes located in the ECA1 region shared in a homozygous state by hydrocephalus cases. Start and stop position (in base pair; Equus caballus EquCab2.0 reference genome [29]), symbol and description of genes located in the region of 1.47 Mb in length that is shared in a homozygous state by hydrocephalus cases. (DOCX 21 kb

Additional file 1: of A nonsense mutation in B3GALNT2 is concordant with hydrocephalus in Friesian horses

Sanger DNA sequencing results for the nonsense mutation. A table with information on all horses that have been sequenced for the nonsense mutation. (DOCX 20 kb

Additional file 3: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity

CNVs randomly selected based on incidence and size validated through qPCR. CNVR identification, chromosome (ECA), start and end position (in bp) and size of the CNVs in the investigated Friesians horse sample is presented, including information on whether the CNV concerned a private (present in 1 horse) or shared (present in 2 horses; the exact same breakpoints were observed) CNV. The designed primers, state of the CNV and results of the qPCR are given. (DOCX 14 kb

Additional file 2: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity

Multidimensional scaling plot of 276 genotyped Friesian horses. Multidimensional scaling plot of 276 genotyped Friesian horses calculated with cluster and mds-plot commands in PLINK software v1.07 [28, 29] using autosomal SNPs. (DOCX 31 kb

Additional file 4: of Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity

Regional association plot (ECA20) of insect bite hypersensitivity in Friesian horses. Significance level based on allele frequency differences between cases (n = 141) and controls (n = 135) using a χ2-test (1df). The horizontal red line is the Bonferroni corrected significance level (P-value = 1.63 × 10− 7). (DOCX 27 kb