75 research outputs found
Knowledge Creation Within the Automobile Industry
Research has identified the enabling factors and inhibitors for successfully implementing knowledge creation and accomplishing its strategic objectives. It is important to understand how these factors interact with each other to improve or inhibit performance. This empirical research presents a framework for finding the fundamental relations between these factors. It proposes strategies for implementing knowledge creation initiatives. The framework mainly focuses on the "what factor" with respect to people and identifies the vital characteristics for the knowledge creation process. It mainly illustrates the parameters of knowledge transfer, which supports knowledge creation, thereby improving organizational performance
Evaluation of the effects of different groove length and thickness of the retainers on the retention of maxillary anterior base metal resin bonded retainers ' an in vitro study
Objectives: The resin-bonded fixed partial dentures have gained immense popularity in recent years as they are
more conservative, esthetic, economic and easily fabricated. However debonding is considered the most common
cause of failure of resin bonded prosthesis. The objective of the study were to compare the effects of different groove
lengths and thickness of retainers on retention of maxillary anterior base metal resin bonded retainers.
Study Design: Twenty five metal dies of maxillary central incisor duplicated from pure typhodont teeth (maxillary
left central incisors) prepared to receive retainer for resin bonded fixed partial denture having different test designs
were made. Five test groups were made with each group having five specimens. Two groups were having preparation
depth of 0.5mm and retention groove lengths of 3mm and 5mm. Two groups had preparation depths of 0.3
and 0.7mm with no groove preparation with retainer thickness of 0.3 and 0.7mm respectively. Fifth group with no
groove preparation and preparation depth of 0.5mm was kept as control for all the groups. All the specimens were
cemented using calibra (Dentsply) resin cement. Each specimen was subjected to tensile loading in vertical direction
on universal testing machine (Instron 5569) at a crosshead speed of 1mm/min. \
Results: Groups with 5mm and 3mm groove length recorded higher mean vertical forces when compared to the
group with no groove preparation. Group with 5mm groove length showed highest mean vertical forces. The group
with 0.7mm retainer recorded higher mean vertical force values when compared to groups with 0.5mm and 0.3mm
retainer thickness. Group with 0.3mm retainer thickness recorded the least mean vertical force value.
Conclusion: Placement of the grooves increased the retention values almost 2 ½ times than the grooveless preparation
and as the thickness of the retainers increased retention values also increased. Retention value was directly
proportional to the groove length and retainer thickness
Reconstruction of a midfacial defect using an intraoral-extraoral combination prosthesis employing magnets: a clinical report
Radical maxillectomy frequently leads to extended defects in hard and soft tissues that result in a connection between
the oral cavities and orbit. If the defect cannot be surgically reconstructed, a combination prosthesis may be
necessary to remedy dysfunction in patient function, comfort, esthetics. For minor defects, enlargement of the base
of the intra oral prosthesis is generally sufficient. Resections that affect more than one third of the maxilla usually
require an intra oral and an extra oral prosthesis that could be assembled and retained in the patient. This clinical
report describes a technique of prosthetic rehabilitation of midfacial defect with a silicone orbital prosthesis and
intra oral obturator that are retained by magnets
Ayurvedic understanding of Central Pontine Myelinolysis - A Case Report
A 56 year old male patient was admitted to S.D.M Ayurveda Hospital, Hassan, Karnataka with the confirmed diagnosis of Central Pontine Myelinolysis (CPM) on 11/12/17. The chief complaints were weakness of both hands and legs, stiffness in both hands and legs, pain in both shoulder joints, slurred speech, difficulty in walking with gait changes. H/O chronic alcoholism. MRI brain showed pontine and basal ganglia diffusion restriction - Acute Pontine Myelinolysis. The serum electrolyte showed serum sodium level as 128 mmol/litre. This disease can be understood as Samana Avruta Vyana in hyponatremic encephalopathy stage and the stage of myelinolysis can be understood as Sarvanga Vata with Kapha Avruta Udana and Vyana. After clinical evaluation, Avarana Chikitsa was started followed by Kevala Vatika Chikitsa and significant improvement was seen. Significant result was observed in subjective and objective parameters after the treatment. The patient was discharged with oral medications for 1 month
Comparative evaluation of bond strength of resin cements with and without 10-methacryloyloxydecyl dihydrogen phosphate (mdp) to zirconia and effect of thermocycling on bond strength ? An in vitro study
To compare bond strength of resin cements with and without 10-Methacryloyloxydecyl Dihydrogen Phosphate (MDP) to zirconia and evaluate effect of thermocycling on bond strength. Standardised test specimens were fabricated as per ADA specification 131. Ea
COMBINATORIAL EFFECT OF D-AMINOACIDS AND TETRACYCLINE AGAINST PSEUDOMONAS AERUGINOSA BIOFILM
Objective: The present study attempted to evaluate the anti-biofilm activity of D-amino acids (D-AAs) on Pseudomonas aeruginosa and determine if the combination of D-AAs with tetracycline enhances the anti-biofilm activity in vitro and ex vivo.Methods: Different D-AAs were tested for antibiofilm activity against wild type P. aeruginosa PAO1 and two multidrug resistant P. aeruginosa clinical strains in the presence of sub inhibitory concentrations of tetracycline using crystal violet microtitre plate assay. Results were further validated using in vitro wound dressing and ex vivo porcine skin models followed by cytotoxicity and hemocompatibility studies.Results: D-tryptophan (5 mmol) showed 61 % reduction in biofilm formation of P. aeruginosa. Interestingly combinatorial effect of 5 mmol D-tryptophan and 0.5 minimum inhibitory concentration (MIC) (7.5µg/ml) tetracycline showed 90% reduction in biofilm formation. 5 mmol D-methionine shows 28 % reduction and combination with tetracycline shows 41% reduction in biofilm formation of P. aeruginosa. D-leucine and D-tyrosine alone or in combination with tetracycline did not show significant anti-biofilm activity. D tryptophan-tetracycline combination could reduce 80 % and 77 % reduction in biofilm formation in two multi drug resistant P. aeruginosa clinical strains. D-tryptophan-tetracycline-combination could also reduce 76% and 66% reduction in biofilm formation in wound dressing model and porcine skin explant respectively. The cytotoxicity and hemocompatibility studies did not show significant toxicity when this combination was used.Conclusion: The results established the potential therapeutic application of D-tryptophan alone or in combination with tetracycline for treating biofilm associated clinical problems caused by P. aeruginosa
Evaluation of keeping quality of canine platelet rich plasma under different storage conditions
Platelet rich plasma (PRP) therapy is an integral part of regenerative medicine as the platelets possess a good healing capacity owing to the presence of a wide variety of growth factors in the platelet granules found in the cytoplasm of the platelet. Autologous PRP was prepared from the blood of the patient itself, without any preservatives. Storage of PRP was one of the main hurdles of the treatment modality. During storage, the platelet counts may get reduced, undergo activation or get contaminated with bacteria as no preservatives are used in the preparation of autologous PRP. Cytological changes and microbial quality of the PRP during storage at 4oC and -20oC for seven days were analysed in this study. Reduction in platelet count and the chance of microbial contamination were less when autologous PRP was stored at -20°C compared to 4°C
B-mode and Doppler ultrasound features of mammary neoplasms and their comparison with normal mammary glands in dogs
Canine mammary neoplasms are naturally occurring non-homogenous group of
tumours with many resemblances to human breast cancer. In female dogs mammary tumours
are of great clinical relevance due to the high prevalence and mortality rate, which varies
according to the histopathological classification and clinical stage. The aim of the study was to
compare the ultrasonographic features of the normal mammary gland with benign and malignant
mammary neoplasms in dogs, through assessed by B-mode and Doppler mode ultrasonography.
Ultrasonographic examination of seven normal mammary glands along with six benign and 12
malignant mammary neoplasms were performed. Among the parameters evaluated by B-Mode
ultrasonography, significant differences were found (p < 0.01) in the tumour margin and invasiveness
of neoplasms, where malignant tumours were invasive with uncircumscribed margin. Significant
difference was also found in the presence of posterior acoustic enhancement (p<0.05) between
benign and malignant mammary neoplasms. Elevated peak systolic velocity of blood flow within
the tumour vessels in malignant mammary neoplasm was the only feature assessed with Doppler
mode having significant difference
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