A Conceptual Architecture for an Event-based Information Aggregation Engine in Smart Logistics

The field of Smart Logistics is attracting interest in several areas of research, including Business Process Management. Awide range of research works are carried out to enhance the capability of monitoring the execution of ongoing logistics processes and predict their likely evolvement. In order to do this, it is crucial to have in place an IT infrastructure that provides the capability of automatically intercepting the digitalised transportation-related events stemming from widespread sources, along with their elaboration, interpretation and dispatching. In this context, we present here the service-oriented software architecture of such an event-based information engine. In particular, we describe the requisites that it must meet. Thereafter, we present the interfaces and subsequently the service-oriented components that are in charge of realising them. The outlined architecture is being utilised as the reference model for an ongoing European research project on Smart Logistics, namely GET Service

A microarray analysis of full depth knee cartilage of ovariectomized rats

<p>Abstract</p> <p>Background</p> <p>This short communication focuses the on articular cartilage and the subchondral bone, both of which play important roles in the development of osteoarthritis (OA). There are indications that estrogen-deficiency, as the post-menopausal state, accelerate the development of OA.</p> <p>Findings</p> <p>We investigated, which extracellular matrix (ECM) protein, proteases and different pro-inflammatory factors was up- or down-regulated in the knee joint tissue in response to estrogen-deficiency in rats induced by ovariectomy. These data support previous findings that several metalloproteinases (MMPs) and cysteine proteases are co-regulated with numerous collagens and proteoglycans that are important for cartilage integrity. Furthermore quite a few pro-inflammatory cytokines were regulated by estrogen deprivation.</p> <p>Conclusion</p> <p>We found multiple genes where regulated in the joint by estrogen-deficiency, many of which correspond well with our current knowledge of the pathogenesis of OA. It supports that estrogen-deficiency (e.g. OVX) may accelerate joint deterioration. However, there are also data that draw attention the need for better understanding of the synergy between proteases and tissue turnover.</p

A Catalog of Reusable Design Decisions for Developing UML- and MOF-based Domain-Specific Modeling Languages

In the process of model-driven development (MDD) of software artifacts, domain-specific modeling languages (DSMLs) are an integral part. They act as the communication vehicle for aligning the requirements of the domain expert with the needs of the software engineer. With the rise of the UML as de facto standard for modeling software systems, MOF/UML-based DSMLs are now widely used for MDD. This paper documents design decisions from ten DSML projects which are based on the MOF/UML and which we conducted over the last years. We present our experiences in the form of reusable decision templates for all decision points detected in each phase of the DSML development process. Furthermore, we report also on identified decision dependencies which may occur within a single decision or between two decisions. (author's abstract)Series: Technical Reports / Institute for Information Systems and New Medi

An Approach to Bridge the Gap between Role Mining and Role Engineering via Migration Guides

Abstract—Mining approaches, such as role mining or organizational mining, can be applied to derive permissions and roles from a system’s configuration or from log files. In this way, mining techniques document the current state of a system and produce current-state RBAC models. However, such currentstate RBAC models most often follow from structures that have evolved over time and are not the result of a systematic rights management procedure. In contrast, role engineering is applied to define a tailored RBAC model for a particular organization or information system. Thus, role engineering techniques produce a target-state RBAC model that is customized for the business processes supported via the respective information system. The migration from a current-state RBAC model to a tailored targetstate RBAC model is, however, a complex task. In this paper, we present a systematic approach to migrate current-state RBAC models to target-state RBAC models. In particular, we use model comparison techniquesto identifydifferences between two RBAC models.Basedon thesedifferences,we derive migrationrulesthat define which elements and element relations must be changed, added, or removed. A migration guide then includes all migration rules that need to be applied to a particular current-state RBAC model to produce the corresponding target-state RBAC model. In addition, we discuss different options for tool support and describe our implementation for the derivation of migration guides which is based on the Eclipse Modeling Framework (EMF). I

An Approach for Consistent Delegation in Process-Aware Information Systems

Abstract. Delegation is an important concept to increase flexibility in authorization and obligation management. Due to the complexity of potential delegation relations, there is a strong need to systematically check the consistency of all delegation assignments. In this paper, we discuss the detection of delegation conflicts based on the formal definitions of a model that supports the delegation of roles, tasks, and duties in a business process context

BPMN Extension forBusiness Process Monitoring *

Abstract: The execution of business processes generates al ot of data representing happenings (also called events) that may be utilized for process monitoring and analysis. This, however, is not supported by typical Business Process Management Systems (BPMSs). Especially,i nm anual executing business process environments, i.e., not drivenbyaBPMS,the correlation of events to processes for monitoring and analysis is not trivial. At design-time, ProcessEvent Monitoring Points are usedinprocess models to specify the locations, where particular events are expected. Therewith, occurring events can be assigned to aprocess during run-time. In this paper,weintroduce an extension to BPMN,which implements this connection between process models and events. We showapplicability of this extension by applying it to alogistics scenario taken from an EU project