Do Tapping Box Technology Increase Local Taxes And District Own Source Revenue?

Taxes have a very important contribution to the state because they are the main income and a manifestation of community involvement in state spending which is regulated in laws. Local taxes as one of the many sources of District Own Source Revenue have a very important role in regional development. This local taxes collection and revenue must be maximized so that the resulting District Own Source Revenue will be maximized as well. The technological innovation or the use of Tapping Box has become an important part of taxes collection and revenue. The study aims to investigate restaurant taxes, the hotel taxes, and entertainment taxes on District Own OktafiyantiSource Revenue receipts mediated by the use of Tapping Box technology. The research took place in the Regional Finance Agency (BAPENDA) of Semarang Regency. This study uses a sample of 60 with 5 years of observation. The sample is the amount of taxes or income per month received from the Regional Taxes Information System then the acquisition of the collected data was analyzed using WarpPLS. The results show that the use of Tapping Box has proven to be able to strengthen the relationship between restaurant taxes and District Own Source Revenue and also the relationship between hotel taxes and District Own Source Revenue. On the other hand, the use of tapping boxes does not strengthen the relationship between the entertainment taxes and District Own Source Revenue. This indicates that the tapping box is often deactivated so that the entertainment business owner's income is not recorded every day, which causes the entertainment taxes paid to the local government to be not optimal

EDUKASI KEJADIAN EFEK SAMPING OBAT PADA MASYARAKAT DI DUSUN MAPONG DESA JURANG JALER, LOMBOK TENGAH

ABSTRAKEfek samping obat atau Adverse Drug Reactions (ADRs) adalah efek obat yang tidak diinginkan yang terjadi selama penggunaan klinis pada dosis normal atau dosis terapi. Efek samping obat dapat berpengaruh pada kualitas hidup pasien, bahkan dapat menyebabkan morbiditas dan mortalitas. Rendahnya pemahaman dan kesadaran masyarakat mengenai obat yang aman, ditambah dengan banyaknya informasi kurang tepat yang beredar melalui media sosial merupakan tantangan baru bagi tenaga kefarmasian untuk melakukan edukasi kejadian efek samping obat yang diberikan kepada masyarakat. Tujuan kegiatan ini untuk memberikan edukasi kepada masyarakat tentang kejadian efek samping obat. Pelaksanaan pra kegiatan meliputi survei lokasi kegiatan di Dusun Mapong Desa Jurang Jaler, Lombok Tengah, proses pembuatan leaflet dan pencetakan leaflet. Pelaksanaan kegiatan dilakukan pada hari Rabu tanggal 29 Juni 2022 bertempat di Rumah Kepala Dusun. Leaflet yang telah disiapkan didistribusikan kepada peserta kegiatan. Pada tahap pasca kegiatan dilakukan evaluasi dilakukan dengan wawancara dan observasi secara lansung menunjukkan adannya peningkatan pengetahuan masyarakat tentang efek samping obat. Edukasi efek samping obat membuka wawasan masyarakat untuk lebih berhati-hati terhadap kemungkinan terjadinya efek samping obat, dan segera melaporkan kejadian efek samping obat kepada Tenaga Kesehatan atau fasilitas pelayanan Kesehatan terdekat untuk meminimalisir kejadian efek samping yang lebih berbahaya. Kata kunci: efek samping obat; edukasi; dusun mapong ABSTRACTAdverse drug reactions (ADRs) are unwanted drug effects that occur during clinical use at normal or therapeutic doses. Drug side effects can affect the patient's quality of life, and can even cause morbidity and mortality. The low level of public understanding and awareness about safe drugs, coupled with a lot of inaccurate information circulating through social media, is a new challenge for pharmacy staff to educate the public on the incidence of adverse drug reactions. The purpose of this activity is to educate the public about the incidence of adverse drug reactions. The pre-activity implementation includes a survey of activity locations in Mapong Hamlet, Jurang Jaler Village, Central Lombok, the process of making leaflets and printing leaflets. The activity was carried out on Wednesday, June 29, 2022 at the Dusun Head's House. Leaflets that have been prepared are distributed to activity participants. At the post-activity stage,. The evaluation was conducted by interviews and direct observations showing an increase in public knowledge about drug side effects education.Education on adverse drug reactions opens the public's insight to be more careful about the possibility of adverse drug reactions, and immediately reports the occurrence of adverse drug reactions to Health Workers or the nearest health service facility to minimize the incidence of more dangerous adverse drug reactions. Keywords: adverse drug reactions; education; mapong hamle

Preliminary Results on the Effect of Magnetic Fields on Anther Culture and Pollen Germination of Citrus clementina Hort. ex Tan.

Exposure to electromagnetic fields seems to modify the biological behaviour of seeds, roots, pollen grains and buds of several plants. This procedure has been also suggested as a tool to improve the utilization of plant species (Firetto et al., 2000, 2001, Petruszewski S., 1996). Since the first haploid embryogenic calli production and plantlet regeneration by anther culture of C. clementina Hort. ex Tan. ‘Nules’ was reported (Germanà et al., 1994), several studies have been carried out to improve both the frequency of microspore embryogenesis and the percentage of plantlet regeneration. To enlarge the number of respondent genotypes and to improve the induction rate (the frequency of pollen grains which form embryoids) are fundamental goals in order to take practical advantage of the haploid potential in Citrus breeding. Successful recovery of haploids depends on several factors like genotype, pre-treatment, pollen development stage, media composition and cultural conditions. This research has been carried out to investigate the effect of magnetic field exposure on the response of Citrus clementina anthers to in vitro culture and the effect of the exposure to three different magnetic frequencies on pollen in vitro germination. The percentage of anthers producing callus was increased by exposure to the magnetic field. Magnetic field exposure also affected pollen germination as well as pollen tube length and morpholog

High Flexibility of RNaseH2 Catalytic Activity with Respect to Non-Canonical DNA Structures

Ribonucleotides misincorporated in the human genome are the most abundant DNA lesions. The 2′-hydroxyl group makes them prone to spontaneous hydrolysis, potentially resulting in strand breaks. Moreover, their presence may decrease the rate of DNA replication causing replicative fork stalling and collapse. Ribonucleotide removal is initiated by Ribonuclease H2 (RNase H2), the key player in Ribonucleotide Excision Repair (RER). Its absence leads to embryonic lethality in mice, while mutations decreasing its activity cause Aicardi–Goutières syndrome. DNA geometry can be altered by DNA lesions or by peculiar sequences forming secondary structures, like G-quadruplex (G4) and trinucleotide repeats (TNR) hairpins, which significantly differ from canonical B-form. Ribonucleotides pairing to lesioned nucleotides, or incorporated within non-B DNA structures could avoid RNase H2 recognition, potentially contributing to genome instability. In this work, we investigate the ability of RNase H2 to process misincorporated ribonucleotides in a panel of DNA substrates showing different geometrical features. RNase H2 proved to be a flexible enzyme, recognizing as a substrate the majority of the constructs we generated. However, some geometrical features and non-canonical DNA structures severely impaired its activity, suggesting a relevant role of misincorporated ribonucleotides in the physiological instability of specific DNA sequences.ISSN:1422-006

Agriculture:Monitoring the effects on humans and various agricultural plants of air pollution by particulate with trace metals.

Agriculture:Monitoring the effects on humans and various agricultural plants of air pollution by particulate with trace metal