Innovative development of the building complex on the basis of environmental and energy-efficient technologies

The objective of the current study was to determine the priorities of innovative development of the building complex on the basis of the analysis of the environmental and energy-efficient technologies that were applied. Analysis of energy efficiency and environmental technologies in the construction industry showed that residential housing consumes 23% of the total primary energy supply in Russia. The construction sector is responsible for 30% of CO2 emissions into the atmosphere. Russia annually spends approximately 170 million tons of fuel equivalents for heating, ventilation and air conditioning of residential housing. Comparing Russia with the countries of similar climatic conditions it should be noted that energy consumption value in Russia is significantly higher (the excess ranges from 24 to 47% depending upon the building). Having analyzed the housing the authors offer the ways of building complex innovative development that mean the following: reindustrialization of material and technical resources of construction companies and the introduction of managerial innovations; the development and application of new high-tech building structures, products and materials that are to ensure the economic and environmental efficiency of buildings’ construction and operation

Innovative development of the building complex on the basis of environmental and energy-efficient technologies

The objective of the current study was to determine the priorities of innovative development of the building complex on the basis of the analysis of the environmental and energy-efficient technologies that were applied. Analysis of energy efficiency and environmental technologies in the construction industry showed that residential housing consumes 23% of the total primary energy supply in Russia. The construction sector is responsible for 30% of CO2 emissions into the atmosphere. Russia annually spends approximately 170 million tons of fuel equivalents for heating, ventilation and air conditioning of residential housing. Comparing Russia with the countries of similar climatic conditions it should be noted that energy consumption value in Russia is significantly higher (the excess ranges from 24 to 47% depending upon the building). Having analyzed the housing the authors offer the ways of building complex innovative development that mean the following: reindustrialization of material and technical resources of construction companies and the introduction of managerial innovations; the development and application of new high-tech building structures, products and materials that are to ensure the economic and environmental efficiency of buildings’ construction and operation

Hydrological, meteorological observations and isotopes sampling results during 2019-2020 at Djankuat Glacier Station in the North Caucasus, Russia

This is an update of a dataset on the long-term complex glaciological, hydrological, meteorological observations and isotopes sampling in an extremely underreported alpine zone of the North Caucasus. The Djankuat research basin is of 9.1 km2, situated on elevations between 2500 – 4000 m, by 30% covered with glaciers. The biggest in the basin Djankuat glacier was chosen as representative of the central North Caucasus during the International Hydrological Decade and is one of 30 'reference' glaciers in the world that have annual mass-balance series longer than 50 years (Zemp et al, 2009). The original dataset covers 2007-2017, this update - 2019-2020. In total, the dataset contains the result of yearly measurements of snow thickness and density; dynamics of snow and ice melting; measurements of water runoff, conductivity, turbidity, temperature, δ18O, δ2H on the main gauging station with a one-hour or several-hours step depending on the parameter; data on δ18O and δ2H sampling of liquid precipitation, snow, ice, firn, groundwater in different parts of the watershed regularly in time during the melting season; precipitation amount, air temperature, relative humidity, shortwave incoming and reflected radiation, longwave downward and upward radiation, atmospheric pressure, wind speed and direction – measured on several automatic weather stations within the basin with 15 min – one-hour step; gradient meteorological measurements to estimate turbulent fluxes of heat and moisture, measuring three components of wind speed at a frequency of 10 hertz to estimate the turbulent impulse heat fluxes over the glacier surface by the eddy covariance method. The observations were held during ablation period June-October and were interrupted in winter. The dataset will be further updated. The dataset can be useful for developing and verifying hydrological, glaciological and meteorological models for high elevation territories, to study impact of climate change on hydrology of mountain regions, using isotopic and hydrochemical approaches to study mountain territories

Protein Kinase Cδ and Calmodulin Regulate Epidermal Growth Factor Receptor Recycling from Early Endosomes through Arp2/3 Complex and Cortactin

The intracellular trafficking of the epidermal growth factor receptor (EGFR) is regulated by a cross-talk between calmodulin (CaM) and protein kinase Cδ (PKCδ). On inhibition of CaM, PKCδ promotes the formation of enlarged early endosomes and blocks EGFR recycling and degradation. Here, we show that PKCδ impairs EGFR trafficking due to the formation of an F-actin coat surrounding early endosomes. The PKCδ-induced polymerization of actin is orchestrated by the Arp2/3 complex and requires the interaction of cortactin with PKCδ. Accordingly, inhibition of actin polymerization by using cytochalasin D or by overexpression of active cofilin, restored the normal morphology of the organelle and the recycling of EGFR. Similar results were obtained after down-regulation of cortactin and the sequestration of the Arp2/3 complex. Furthermore we demonstrate an interaction of cortactin with CaM and PKCδ, the latter being dependent on CaM inhibition. In summary, this study provides the first evidence that CaM and PKCδ organize actin dynamics in the early endosomal compartment, thereby regulating the intracellular trafficking of EGFR