2,259 research outputs found

    Magnetization switching in nanoscale ferromagnetic grains: simulations with heterogeneous nucleation

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    We present results obtained with various types of heterogeneous nucleation in a kinetic Ising model of magnetization switching in single-domain ferromagnetic nanoparticles. We investigate the effect of the presence of the system boundary and make comparison with simulations on periodic lattices. We also study systems with bulk disorder and compare how two different types of disorder influence the switching behavior.Comment: 3 pages, 4 Postscript figure

    Atyidae and Palaemonidae (Crustacea: Decapoda: Caridea) of Bocas del Toro, Panama.

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    The present contribution is a preliminary report on the freshwater caridean fauna of Bocas del Toro province, northeastern Panama, based on field collections carried out during a Shrimp Taxonomy Workshop at the STRI station in Bocas del Toro in August 2008. A total of eight species from two families, Atyidae and Palaemonidae, were collected at 17 different collection sites in the rivers, streams and ponds on several islands of the Bocas del Toro archipelago and the adjacent mainland. The species reported herein are Atya scabra (Leach, 1815), Jonga serrei (Bouvier, 1909), Micratya poeyi (Guérin-Méneville, 1855), Potimirim glabra (Kingsley, 1878), P. potimirim (Müller, 1881) (Atyidae), Palaemon pandaliformis (Stimpson, 1871), Macrobrachium acanthurus (Wiegmann, 1836) and M. crenulatum Holthuis, 1950 (Palaemonidae). The record of J. serrei is the first for Panama, and M. poeyi a P. glabra the first for Bocas del Toro province

    Spatial Modulation Microscopy for Real-Time Imaging of Plasmonic Nanoparticles and Cells

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    Spatial modulation microscopy is a technique originally developed for quantitative spectroscopy of individual nano-objects. Here, a parallel implementation of the spatial modulation microscopy technique is demonstrated based on a line detector capable of demodulation at kHz frequencies. The capabilities of the imaging system are shown using an array of plasmonic nanoantennas and dendritic cells incubated with gold nanoparticles.Comment: 3 pages, 4 figure

    A framework to evaluate land degradation and restoration responses for improved planning and decision-making.

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    Made available in DSpace on 2020-05-14T20:20:36Z (GMT). No. of bitstreams: 1 A-framework-to-evaluate-land-degradation-and-restoration-responses-for-improved-planning-and-decision-making.pdf: 3147852 bytes, checksum: e97d8b89271bd75dfcdff4bd682b112d (MD5) Previous issue date: 2020bitstream/item/212992/1/A-framework-to-evaluate-land-degradation-and-restoration-responses-for-improved-planning-and-decision-making.pd

    Atrial fibrillation impairs the diagnostic performance of cardiac natriuretic peptides in dyspneic patients. results from the BACH Study (Biomarkers in ACute Heart Failure)

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    Objectives: The purpose of this study was to assess the impact of atrial fibrillation (AF) on the performance of mid-region amino terminal pro-atrial natriuretic peptide (MR-proANP) in comparison with the B-type peptides (BNP and NT-proBNP) for diagnosis of acute heart failure (HF) in dyspneic patients. Background: The effects of AF on the diagnostic and prognostic performance of MR-proANP in comparison with the B type natriuretic peptides have not been previously reported. Methods: A total of 1,445 patients attending the emergency department with acute dyspnea had measurements taken of MR-proANP, BNP, and NT-proBNP values on enrollment to the BACH trial and were grouped according to presence or absence of AF and HF. Results: AF was present in 242 patients. Plasma concentrations of all three peptides were lowest in those with neither AF nor HF and AF without HF was associated with markedly increased levels (p < 0.00001). HF with or without AF was associated with a significant further increment (p < 0.00001 for all three markers). Areas under receiver operator characteristic curves (AUCs) for discrimination of acute HF were similar and powerful for all peptides without AF (0.893 to 0.912; all p < 0.001) with substantial and similar reductions (0.701 to 0.757) in the presence of AF. All 3 peptides were independently prognostic but there was no interaction between any peptide and AF for prediction of all-cause mortality. Conclusions: AF is associated with increased plasma natriuretic peptide (MR-proANP, BNP and NT-proBNP) levels in the absence of HF. The diagnostic performance of all three peptides is impaired by AF. This warrants consideration of adjusted peptide thresholds for diagnostic use in AF and mandates the continued search for markers free of confounding by AF

    A framework to evaluate land degradation and restoration responses for improved planning and decision-making

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    Avoiding, reducing or reversing land degradation will require increased restoration investments, carefully targeted and implemented to maximize environmental, economic and social benefits. Our objective was to develop a multi-criteria framework to assess effectiveness of land degradation responses for enhanced land use planning and restoration by evaluating both direct biophysical and socio-economic responses and indirect effects of various restoration strategies. The effectiveness of restoration responses is demonstrated for degraded forestland using a comprehensive literature review and case study in Nepal. The results show that most forestland restoration responses have an ecological focus with tree planting being the dominant direct response and economic and financial instruments the indirect responses. The results confirmed that environmental desirability was the dominant factor and economic feasibility was secondary for assessing restoration responses. Cultural acceptability was given the least consideration. Among sub-criteria, improved vegetative structure was the dominant restoration response. This study, originating from the Land Degradation and Restoration Assessment of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services, supports the view that the scientific community and decision-makers must give greater attention to cultural, social, technical, and political dimensions that influence the outcomes of restoration responses to solve the pervasive problem of land degradation

    Development and validation of a life expectancy estimator for multimorbid older adults: A cohort study protocol

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    Background Older multimorbid adults have a high risk of mortality and a short life expectancy (LE). Providing high-value care and avoiding care overuse, including of preventive care, is a serious challenge among multimorbid patients. While guidelines recommend to tailor preventive care according to the estimated LE, there is no tool to estimate LE in this specific population. Our objective is therefore to develop an LE estimator for older multimorbid adults by transforming a mortality prognostic index, which will be developed and internally validated in a prospective cohort. Methods and analysis We will analyse data of the Optimising Therapy to Prevent Avoidable Hospital Admissions in Multimorbid Older People cohort study in Bern, Switzerland. 822 participants were included at hospitalisation with age of 70 years or older, multimorbidity (three or more chronic medical conditions) and polypharmacy (use of five drugs or more for >30 days). All-cause mortality will be assessed during 3 years of follow-up. We will apply a flexible parametric survival model with backward stepwise selection to identify the mortality risk predictors. The model will be internally validated using bootstrapping techniques. We will derive a point-based risk score from the regression coefficients. We will transform the 3-year mortality prognostic index into an LE estimator using the Gompertz survival function. We will perform a qualitative assessment of the clinical usability of the LE estimator and its application. We will conduct the development and validation of the mortality prognostic index following the Prognosis Research Strategy (PROGRESS) framework and report it following the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) statement. Ethics and dissemination Written informed consent by patients themselves or, in the case of cognitive impairment, by a legal representative, was required before enrolment. The local ethics committee (Kantonale Ethikkommission Bern) has approved the study. We plan to publish the results in peer-reviewed journals and present them at national and international conferences
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