A study on platelet count and their indices-mean platelet volume and platelet distribution width and their prognostic significance in acute coronary syndrome in tertiary care hospital

BACKGROUND AND OBJECTIVES: Cardiovascular disease is an epidemic of modern society. Myocardial infarction is a major cause of morbidity and mortality in the world. Despite the impressive strides in diagnosis and management over the past four decades, acute myocardial infarction continues to be a major public health problem in industrialized world and is becoming an increasingly important problem in developing countries. In United States, 13 million individuals have ischemic heart disease, > 6 million have angina pectoris,>7 million have persistent myocardial infarction. The study “The platelet count and mean platelet volume and platelet distribution width in myocardial infarction “was done to assess the relationship between mean platelet volume (MPV) and the occurrence of acute myocardial infarction and to find out its association with the risk factors and short term prognosis after myocardial infarction. METHODS: With rigid criteria 65 patients were selected carefully and were evaluated on social, clinical and laboratory aspects after institutional ethical clearance with an informed consent.35 subjects were taken as controls. The data were entered in Microsoft Excel spread sheet and analysed statistically. RESULTS: There were 45 males and 20 females in patient group. There were25 males and 10 females in control group. The mean age of the patient group was 52.98±15 and that of the control group 49.03±10.36 (p value 0.167 –not statistically significant). The prevalence of smoking systemic hypertension, and diabetes mellitus were noticed in both group with statistical significance. The mean platelet count of the cases was 4.98±0.23lakhs/mm³ and that of the controls was 1.29±0.42 Lakhs/mm³ (p value 0.050 statistically significant). The MPV of the cases ranged from 8.4 to 12 femtolitres with a mean of 10.2 ± 1.1 femtolitres. The MPV of the controls ranged from 7 to 10.60 femtolitres with mean of 8.29±0.9 femtolitres. The difference between the two was statistically significant. (p value 0.001 significant). INTERPRETATION AND CONCLUSION: There was significantly relationship between age, sex, smoking, diabetes mellitus and systemic hypertension platelet count, MPV, PDW.MPV was found to be independent of aspirin intake. There was correlation observed between MPV and short term prognosis like left ventricular dysfunction and death. According to Assiri [et al.] (2012) stated that platelet volume parameters mainly MPV and PDW are, available and inexpensive markers, detected significantly raised in patients admitted with acute coronary syndrome. From this observation, they suggested to use platelet parameters used to screen patients presenting to emergency room with chest pain suspected to have acute coronary syndrome

Dynamic Mobile Cloud Eco System Security - A Review

Mobile cloud computing is the technique of using cloud technology and various rich mobile applications are intended to be able to run on a variety of mobile devices using the technique called mobile cloud computing. In recent years, huge amounts of data are stored by the clients which are much more easily to the integration of cloud platforms into mobile systems. The ways of security used in portable device settings are one of the key challenges in this respect as the number of people using smartphones continues to rise. None of the models that have been developed with confidence and privacy for precaution of data in mobile cloud systems are impervious to destructive attacks, despite countless attempts. While mobile cloud computing has great potential, security, privacy, viability, and accessibility concerns must still be considered by both consumers and businesses. Additionally, it emphasizes the use of Canny Card Web Services (CCWS) competition to enhance mobile cloud computing security with IOT. This paper has been presented with more than one user application: a smart house and a smart parking in an educational institution, in the inclusion of IOT with cloud computing for demonstrating various admittance control and endorsement requirement. A review regarding this paper concentrated on a little model that is intended the security and privacy ensureability of data in mobile clouds. Additionally, to manage mobile cloud security difficulties and challenges, it is important to look at the current situation with regard to cloud security breaches, the weaknesses of mobile cloud devices, and the best ways to address these issues in the near future with regard to mobile device management and mobile data protection

On Fractional Helmholtz Equations

MSC 2010: 26A33, 33E12, 33C60, 35R11In this paper we derive an analytic solution for the fractional Helmholtz equation in terms of the Mittag-Leffler function. The solutions to the fractional Poisson and the Laplace equations of the same kind are obtained, again represented by means of the Mittag-Leffler function. In all three cases the solutions are represented also in terms of Fox's H-function

Assessment of physiochemical and microbial concentrations in different fresh waters in Tiruchirappalli city: A special emphasize on their correlation

The six fresh water samples belonging to three different sources (Cauvery river water, ground water and bottle drinking water) from Tiruchirappalli city were collected (bi-monthly sampling) during April 2014 to June 2014 for physiochemical and microbiological study. Bacterial and physiochemical parameters levels were two to ten folds higher in river water sample than in ground and bottle water due to discharges of municipal sewage and human activities. The elevated bacterial communities in May month indicated that which received waste materials from landside and more visits due to the lack of water scarcity. The higher pollution index (PI) ratio (>1) were observed in river water samples (than the ground and bottle water) in all the three months indicate the human fecal matters were responsible for water pollution. The order of decreasing microbial and physiochemical values were: May month > April month > June month. The correlation proved that physicochemical parameters were strongly supported to microbial communities due to addition of rich organic content in the water bodies from different pollution sources. Based on the report, this study was suggesting that throughout impoundment is needed to protect fresh water sources

Anti (Q, L)-Fuzzy Subhemirings of a Hemiring

In this paper, an attempt has been made to study the algebraic nature of an anti (Q, L)-fuzzy subhemirings of a hemi ring

Efficacy of antibacterial activity of garlic cloves from Tamil Nadu and Jowai region

Background:The development of antibiotic resistance has become a global health challenge which is causing ineffectiveness of the available antibacterial agents leading to increase in diseases and death rate. Therefore this study intends to investigate the antibacterial action of Aqueous Garlic Extract (AGE) against 9 multidrug-resistant gram-positive and gram-negative bacterial isolates, including Staphylococcus aureus, Enterococcus species, ß hemolytic streptococcus, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, Escherichia coli, Vibrio cholerae and Serretia marscenes.Methods:Antibacterial activity of different concentrations of AGE by well-diffusion method was recorded by measuring the diameter of zone of inhibition. The Tamil Nadu garlic cloves as well as Jowai region garlic cloves showed antibacterial activity against both GPC and GNR.Results: The maximum zone of inhibition was observed in Tamil Nadu garlic than that of Jowai region, but the only bacteria which showed a better zone of inhibition with Jowai region than Tamil Nadu garlic was Pseudomonas aeruginosa.Conclusion:Thus our study reveals that garlic not only makes the food more spicy & edible with its flavour but can also be used as an effective antibacterial agents against MDR gram positive & gram negative bacteria.

A Search for Blues Brothers: X-ray Crystallographic/Spectroscopic Characterization of the Tetraarylbenzidine Cation Radical as a Product of Aging of Solid Magic Blue

Magic blue (MB+˙ SbCl6− salt), i.e. tris-4-bromophenylamminium cation radical, is a routinely employed one-electron oxidant that slowly decomposes in the solid state upon storage to form so called ‘blues brothers’, which often complicate the quantitative analyses of the oxidation processes. Herein, we disclose the identity of the main ‘blues brother’ as the cation radical and dication of tetrakis-(4-bromophenyl)benzidine (TAB) by a combined DFT and experimental approach, including isolation of TAB+˙ SbCl6− and its X-ray crystallography characterization. The formation of TAB in aged magic blue samples occurs by a Scholl-type coupling of a pair of MB followed by a loss of molecular bromine. The recognition of this fact led us to the rational design and synthesis of tris(2-bromo-4-tert-butylphenyl)amine, referred to as ‘blues cousin’ (BC: Eox1 = 0.78 V vs. Fc/Fc+, λmax(BC+˙) = 805 nm, εmax = 9930 cm−1 M−1), whose oxidative dimerization is significantly hampered by positioning the sterically demanding tert-butyl groups at the para-positions of the aryl rings. A ready two-step synthesis of BC from triphenylamine and the high stability of its cation radical (BC+˙) promise that BC will serve as a ready replacement for MB and an oxidant of choice for mechanistic investigations of one-electron transfer processes in organic, inorganic, and organometallic transformations