Control of infectious lameness in sheep

Lameness in sheep remains a significant welfare and economic issue for many UK sheep farms. The principle causes of lameness are the infectious foot diseases footrot and contagious ovine digital dermatitis. This article will review the recent research on the microbial aetiology, epidemiology, prevention and treatment of both diseases and the application of this knowledge into farm specific control plans utilising the Five Point Plan framework. </jats:p

Sheep and farm level factors associated with contagious ovine digital dermatitis: A longitudinal repeated cross-sectional study of sheep on six farms

Contagious ovine digital dermatitis (CODD) is a cause of severe lameness in sheep in the UK currently affecting approximately 50% of farms. Six farms were studied in North Wales to investigate (1) the prevalence dynamics of CODD, (2) the association between sheep with CODD and potential risk factors and (3) the impact of CODD on lameness in sheep. The farms were visited at approximately two-month intervals between June 2012 and October 2013 and 6515 sheep were examined. The mean sheep level prevalence of CODD varied between farms (2.5–11.9%). Within farms, prevalence may increase in the late summer/early autumn and after housing. Environmental risk factors included larger flocks, lowland pasture, lush pasture and poached pasture. Co-infection of a foot with footrot was strongly associated with CODD in that foot (OR: 7.7 95% CI: 3.9–15.5

Watery mouth disease in neonatal lambs: a systematic literature review

Watery mouth disease is considered to be a significant cause of neonatal mortality in lambs. The clinical signs are strongly associated with an endotoxaemia produced as a result of the lysis of Gram-negative bacteria. It has been associated with mass antibiosis to neonatal lambs at birth, a practice which is now untenable. It can be prevented in many cases through the timely administration of good quality colostrum and a hygienic birth environment. However, despite this, much remains unknown about the specific aetiopathogenesis. Alternative strategies for prevention, treatment and control are required, particularly when colostrum quality is poor, or delivery is absent, and where unhygienic conditions predominate. </jats:p

Determining the cause of stillbirth in Kumasi, Ghana

ObjectiveTo classify causeâ ofâ death (COD) for stillbirths occurring in a major referral hospital in Kumasi, Ghana.MethodsIn a retrospective review conducted between June 8, 2011, and June 12, 2012, detailed information was collected on all stillbirths delivered at Komfo Anokye Teaching Hospital in Kumasi, Ghana. Patient records were independently reviewed by investigators using the Perinatal Society of Australia and New Zealand’s Perinatal Death Classification system to determine COD for each case.ResultsCOD was analyzed in 465 stillbirth cases. The leading causes of death were hypoxic interpartum death (105, 22.6%), antepartum hemorrhage (67, 14.4%), hypertension (52, 11.2%), and perinatal infection (32, 6.9%). One hundred and fifty seven (33.8%) stillbirths were classified as unexplained antepartum deaths.ConclusionsThis evaluation of stillbirth in a busy, tertiary care hospital in Kumasi, Ghana provides crucial insight into the high volume of stillbirth in Ghana as well as its medical causes. The study demonstrated the high rate of stillbirth attributed to hypoxic intrapartum events, placental abruption, preâ eclampsia, and unspecified bacterial infections. Yet, our rate of unexplained stillbirths underscores the need for a stillbirth classification system that thoughtfully integrates the needs and limitations of lowâ resource settings as unexplained stillbirth rates are a common indicator of the effectiveness of a classification system.This study demonstrates the high rate of stillbirth associated with hypoxic intrapartum events, placental abruption, preâ eclampsia, and infection at a tertiary hospital in Ghana.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151859/1/ijgo12930_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151859/2/ijgo12930.pd

Root causes and social consequences of birth injuries in Western Uganda

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138287/1/ijgo12257.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138287/2/ijgo12257_am.pd

Barriers to Early Presentation amongst Rural Residents Experiencing Symptoms of Colorectal Cancer : A Qualitative Interview Study

Peer reviewedPublisher PD

Long-term fertilization alters the relative importance of nitrate reduction pathways in salt marsh sediments

Salt marshes provide numerous valuable ecological services. In particular, nitrogen (N) removal in salt marsh sediments alleviates N loading to the coastal ocean. N removal reduces the threat of eutrophication caused by increased N inputs from anthropogenic sources. It is unclear, however, whether chronic nutrient over-enrichment alters the capacity of salt marshes to remove anthropogenic N. To assess the effect of nutrient enrichment on N cycling in salt marsh sediments, we examined important N cycle pathways in experimental fertilization plots in a New England salt marsh. We determined rates of nitrification, denitrification, and dissimilatory nitrate reduction to ammonium (DNRA) using sediment slurry incubations with 15 N labeled ammonium or nitrate tracers under oxic headspace (20% oxygen / 80% helium). Nitrification and denitrification rates were more than ten-fold higher in fertilized plots compared to control plots. By contrast, DNRA, which retains N in the system, was high in control plots but not detected in fertilized plots. The relative contribution of DNRA to total nitrate reduction largely depends on the carbon/nitrate ratio in the sediment. These results suggest that long-term fertilization shifts N cycling in salt marsh sediments from predominantly retention to removal. Long-term fertilization alters the relative importance of nitrate reduction pathways in salt marsh sediments: NO 3 - reduction in salt marsh sediments (PDF Download Available). Available from: https://www.researchgate.net/publication/305480944_Long-term_fertilization_alters_the_relative_importance_of_nitrate_reduction_pathways_in_salt_marsh_sediments_NO_3_-_reduction_in_salt_marsh_sediments [accessed Jun 6, 2017]