Analyticity and the NcN_c counting rule of SS matrix poles

By studying $\pi\pi$ scattering amplitudes in the large $N_c$ limit, we clarify the $N_c$ dependence of the $S$ matrix pole position. It is demonstrated that analyticity and the $N_c$ counting rule exclude the existence of $S$ matrix poles with ${\cal M}, \Gamma\sim O(1)$. Especially the properties of $\sigma$ and $f_0(980)$ with respect to the $1/N_c$ expansion are discussed. We point out that in general tetra-quark resonances do not exist.Comment: This paper replaces hep-ph/0412175. The latter is withdraw

Corrigendum to CNTNAP2 variants affect early language development in the general population

Corrigendum to CNTNAP2 variants affect early language development in the general population A. J. O. Whitehouse, D. V. M. Bishop, Q. W. Ang, C. E. Pennell and S. E. Fisher Genes Brain Behav (2011) doi: 10.1111/j.1601-183X.2011.00684.x. The authors have detected a typographical error in the Abstract of this paper. The error is in the fifth sentence, which reads: ‘‘On the basis of these findings, we performed analyses of four-marker haplotypes of rs2710102–rs759178–rs17236239–rs2538976 and identified significant association (haplotype TTAA, P = 0.049; haplotype GCAG,P = .0014).’’ Rather than ‘‘GCAG’’, the final haplotype should read ‘‘CGAG’’. This typographical error was made in the Abstract only and this has no bearing on the results or conclusions of the study, which remain unchanged. Reference Whitehouse, A. J. O., Bishop, D. V. M., Ang, Q. W., Pennell, C. E. & Fisher, S. E. (2011) CNTNAP2 variants affect early language development in the general population. Genes Brain Behav 10, 451–456. doi: 10.1111/j.1601-183X.2011.00684.x

Anisotropic Generalized Bayesian Coherent Point Drift for Point Set Registration

Registration is highly demanded in many real-world scenarios such as robotics and automation. Registration is challenging partly due to the fact that the acquired data is usually noisy and has many outliers. In addition, in many practical applications, one point set (PS) usually only covers a partial region of the other PS. Thus, most existing registration algorithms cannot guarantee theoretical convergence. This article presents a novel, robust, and accurate three-dimensional (3D) rigid point set registration (PSR) method, which is achieved by generalizing the state-of-the-art (SOTA) Bayesian coherent point drift (BCPD) theory to the scenario that high-dimensional point sets (PSs) are aligned and the anisotropic positional noise is considered. The high-dimensional point sets typically consist of the positional vectors and normal vectors. On one hand, with the normal vectors, the proposed method is more robust to noise and outliers, and the point correspondences can be found more accurately. On the other hand, incorporating the registration into the BCPD framework will guarantee the algorithm's theoretical convergence. Our contributions in this article are three folds. First, the problem of rigidly aligning two general PSs with normal vectors is incorporated into a variational Bayesian inference framework, which is solved by generalizing the BCPD approach while the anisotropic positional noise is considered. Second, the updated parameters during the algorithm's iterations are given in closed-form or with iterative solutions. Third, extensive experiments have been done to validate the proposed approach and its significant improvements over the BCPD

Closed-Loop Magnetic Manipulation for Robotic Transesophageal Echocardiography

This paper presents a closed-loop magnetic manipulation framework for robotic transesophageal echocardiography (TEE) acquisitions. Different from previous work on intracorporeal robotic ultrasound acquisitions that focus on continuum robot control, we first investigate the use of magnetic control methods for more direct, intuitive, and accurate manipulation of the distal tip of the probe. We modify a standard TEE probe by attaching a permanent magnet and an inertial measurement unit sensor to the probe tip and replacing the flexible gastroscope with a soft tether containing only wires for transmitting ultrasound signals, and show that 6-DOF localization and 5-DOF closed-loop control of the probe can be achieved with an external permanent magnet based on the fusion of internal inertial measurement and external magnetic field sensing data. The proposed method does not require complex structures or motions of the actuator and the probe compared with existing magnetic manipulation methods. We have conducted extensive experiments to validate the effectiveness of the framework in terms of localization accuracy, update rate, workspace size, and tracking accuracy. In addition, our results obtained on a realistic cardiac tissue-mimicking phantom show that the proposed framework is applicable in real conditions and can generally meet the requirements for tele-operated TEE acquisitions.Comment: Accepted by IEEE Transactions on Robotics. Copyright may be transferred without notice, after which this version may no longer be accessibl

Two Novel Genetic Variants in the Mineralocorticoid Receptor Gene Associated with Spontaneous Preterm Birth

Background: Preterm birth is the leading cause of mortality and morbidity in newborn infants. Its etiology is multifactorial with genes and environmental factors, including chronic maternal stress, contributing to its risk. Our objective was to investigate whether single nucleotide polymorphisms (SNPs) in genes involved in the stress response are associated with spontaneous preterm birth using a candidate gene approach. Methods: A total of 210 cases (singleton spontaneous preterm birth at \u3c37 \u3eweeks) and 412 controls (singleton term birth at 38–42 weeks without a history of preterm birth) were studied. High quality maternal DNA was available from saliva samples of 190 cases and 369 controls and compared. Sociodemographic and medical data were collected. Sixteen SNPs, either tag SNPs located in key genes involved in the stress response identified in the Preterm Birth Genome Project database or SNPs found to be associated with adverse mental health outcomes in the published literature, were selected for genotyping and sequencing. SNPs were genotyped using Taqman® SNP genotyping assays. Univariate and multivariate logistic regression were performed. Results: Multivariate analysis showed that two SNPs located in the mineralocorticoid receptor gene were significantly associated with spontaneous preterm birth: rs17484063 (OR 0.50, p = 0.038) and rs2883929 (OR 0.49, p = 0.017), regardless of maternal age, smoking, alcohol use, educational status, and history of spontaneous miscarriage. Conclusion: This report demonstrates an association between mineralocorticoid receptor gene polymorphisms, rs17484063 and rs2883929, and preterm birth, supporting a role for genetics in the association between chronic maternal stress and preterm birth. Potentially, this information may be used to predicting the risk of having a preterm delivery

The role of early childhood development and education (ECDE) in supporting learning and well-being in rural early childhood and primary schools in South Africa

This paper examines how early childhood and primary schools can be constructed as enabling spaces to improve the learning and well-being of children aged six to nine who live in multidimensionally poor, low-resourced rural communities in South Africa. Quality early childhood development and education (ECDE) can be the catalyst to break the cycle of poverty for many young children in rural areas. A systematic review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses flowchart. A comprehensive search strategy using electronic databases and hand searches systematically whittled down an initial database of 30,080 articles to 16 articles for this study. A thematic analysis identified enablers and constraints for supporting children’s learning and well-being across three themes: (1) infrastructure, educational resources and child agency (2) initial teacher education (ITE) and (3) socioeconomic status. The findings and discussion highlight child agency as an enabler to learning and well-being and the structural and pedagogical challenges of implementing ITE curricula specific to rural educational contexts

Reliable Hybrid Mixture Model for Generalized Point Set Registration

Point set registration (PSR) is an essential problem in the field of surgical navigation and augmented reality (AR). In surgical navigation, the aim of registration is mapping the pre-operative space to the intra-operative space. This article introduces a reliable hybrid mixture model, in which the reliability of the normal vectors in the generalized point set (GPS) is examined and exploited. The motivation of considering the reliability of orientation information is that normal vectors cannot be estimated or measured accurately in the clinic. The point set (PS) is divided into two subsets according to the reliability of normal vectors. PSR is cast into the maximum likelihood estimation (MLE) problem. The expectation maximization (EM) framework is used to solve the MLE problem. In the E-step, the posterior probabilities between points in two PSs are computed. In the M-step, the transformation matrix and model components are updated by optimizing the objective function. We have demonstrated through extensive experiments on the human femur bone PS that the proposed algorithm outperforms the state-of-the-art ones in terms of accuracy, robustness, and convergence speed

Highly phosphorescent platinum(II) emitters: photophysics, materials and biological applications

published_or_final_versio

Effervescent Water Coagulant from Citrofortunella Microcarpa Scraps for Water Treatment

As the Philippines experiences increasing alerts in water pollution, this study aims to create a Calamansi-based effervescent water coagulant to increase the accessibility of purified water to Filipinos. The study makes use of Citrofortunella microcarpa (Calamansi), a small citrus fruit abundant in the Philippines. Calamansi has a big contribution in the production of agricultural waste as the fruit is mainly utilized for its pulp; therefore, the researchers focused on the usage of Calamansi’s peels and seeds, given their ability to absorb minute particles and to kill bacteria. Disposed Calamansi scraps were powderized and mixed with other components to form an eco-friendly effervescent water coagulant. The researchers assessed the efficacy of the Calamansi coagulant by comparing it to Ferric chloride (FeCl3), an existing chemical water coagulant, and testing ten trials of each sample in a contaminated soil-water mixture. The group’s findings suggest that the effervescent Calamansi coagulant presented a higher efficacy in water treatment than FeCl3, with its pH, electrical conductivity (EC), total dissolved solids (TDS), and salinity readings all within the standard range. The Calamansi coagulant accumulated more residue than the FeCl3 sample. The study demonstrates that Calamansi seed and peel waste offer a great alternative to chemical-based coagulants in water treatment