Congenital hypothyroidism in neonates

Context: Congenital hypothyroidism (CH) is one of the most common preventable causes of mental retardation in children and it occurs in approximately 1:2,000-1:4,000 newborns. Aims and Objectives: The aim of this study is to determine the frequency of CH in neonates. Settings and Design: This cross-sectional study was conducted in neonatal units of the Department of Pediatrics Unit-I, King Edward Medical University/Mayo Hospital, Lahore and Lady Willington Hospital Lahore in 6 months (January-June 2011). Materials and Methods: Sample was collected by non-probability purposive sampling. After consent, 550 newborn were registered for the study. Demographic data and relevant history was recorded. After aseptic measures, 2-3 ml venous blood analyzed for thyroid-stimulating hormone (TSH) level by immunoradiometric assay. Treatment was started according to the individual merit as per protocol. Statistical Analysis Used: Data was analyzed by SPSS 17 and Chi-square test was applied to find out the association of CH with different variables. Results: The study population consisted of 550 newborns. Among 550 newborns, 4 (0.8%) newborns had elevated TSH level. CH had statistically significant association with mother′s hypothyroidism (P value 0.000) and mother′s drug intake during the pregnancy period (P value 0.013). Conclusion: CH is 0.8% in neonates. It has statistically significant association with mother′s hypothyroidism and mother′s drug intake during pregnancy

Spatial Distribution and Trends of Fertility Differentials in Toba Tek Singh District, Punjab-Pakistan

This study examines socio-economic and demographic factors as fertility differentials and draws conclusions upon data collected from some selected rural and urban localities of Toba Tek Sing-Punjab. The analysis carried to examine change in fertility trends and preferences in relation to children ever born to currently married women. The ideal family size from the both localities is 3.98 which, is still reckoned high as compared to the (NGRP) National Growth Rate in Pakistan which is 3.80. The dependent variable is reproductive preference measured by a single indicator- ideal no. of children and gender in both urban and rural localities as same study was conducted by National Institute of Population Studies (NIPS) in 1990-91 and 2006-07. In Pakistan number of demographic surveys has revealed that woman of reproductive age generally prefer more children than their own preferred family size. The aim of this study is to contribute into the existing literature on the geographical patterns of fertility differentials in a district of the Punjab. This will help planners to formulate more effective fertility related policies and programmes in the country. This is also a continuum of DHS conducted in mid 1980s to elaborate fertility patterns among married couples. The goal is to dig deeper into the relationship between education and fertility has been a central focus within demography and related social sciences. Higher education is associated with higher age at first birth and lower number of children discussed the implication of findings in the context of policy framework to enhance the public awareness about the small family in context with high quality life. Higher fertility in a country like Pakistan is rooted in cultural believes about children and number, pre-natal control measures should be targeted more at women attitude to large family. This is to provide policy makers with an understanding of the potential demand for fertility control and help in formulating policies to reduce fertility and improve socio-economic climate of the district

Spatial Distribution and Trends of Fertility Differentials in Toba Tek Singh District, Punjab-Pakistan

This study examines socio-economic and demographic factors as fertility differentials and draws conclusions upon data collected from some selected rural and urban localities of Toba Tek Sing-Punjab. The analysis carried to examine change in fertility trends and preferences in relation to children ever born to currently married women. The ideal family size from the both localities is 3.98 which, is still reckoned high as compared to the (NGRP) National Growth Rate in Pakistan which is 3.80. The dependent variable is reproductive preference measured by a single indicator- ideal no. of children and gender in both urban and rural localities as same study was conducted by National Institute of Population Studies (NIPS) in 1990-91 and 2006-07. In Pakistan number of demographic surveys has revealed that woman of reproductive age generally prefer more children than their own preferred family size. The aim of this study is to contribute into the existing literature on the geographical patterns of fertility differentials in a district of the Punjab. This will help planners to formulate more effective fertility related policies and programmes in the country. This is also a continuum of DHS conducted in mid 1980s to elaborate fertility patterns among married couples. The goal is to dig deeper into the relationship between education and fertility has been a central focus within demography and related social sciences. Higher education is associated with higher age at first birth and lower number of children discussed the implication of findings in the context of policy framework to enhance the public awareness about the small family in context with high quality life. Higher fertility in a country like Pakistan is rooted in cultural believes about children and number, pre-natal control measures should be targeted more at women attitude to large family. This is to provide policy makers with an understanding of the potential demand for fertility control and help in formulating policies to reduce fertility and improve socio-economic climate of the district

Characteristics of case patients (with neurological complications) and control patients (without neurological complications).

Characteristics of case patients (with neurological complications) and control patients (without neurological complications).</p

Psyllium-Husk-Assisted Synthesis of ZnO Microstructures with Improved Photocatalytic Properties for the Degradation of Methylene Blue (MB)

Wastewater from the textile industry is chronic and hazardous for the human body due to the presence of a variety of organic dyes; therefore, its complete treatment requires efficient, simple, and low cost technology. For this purpose, we grew ZnO microstructures in the presence of psyllium husk, and the role of psyllium husk was to modify the surface of the ZnO microstructures, create defects in the semiconducting crystal structures, and to alter the morphology of the nanostructured material. The growth process involved a hydrothermal method followed by calcination in air. Additionally, the psyllium husk, after thermal combustion, added a certain value of carbon into the ZnO nanomaterial, consequently enhancing the photocatalytic activity towards the degradation of methylene blue. We also investigated the effect of varying doses of photocatalyst on the photocatalytic properties towards the photodegradation of methylene blue in aqueous solution under the illumination of ultraviolet light. The structure and morphology of the prepared ZnO microstructures were explored by scanning electron microscopy (SEM) and powder X-ray diffraction (XRD) techniques. The degradation of methylene blue was monitored under the irradiation of ultraviolet light and in the dark. Also, the degradation of methylene blue was measured with and without photocatalyst. The photodegradation of methylene blue is highly increased using the ZnO sample prepared with psyllium husk. The photodegradation efficiency is found to be approximately 99.35% for this sample. The outperforming functionality of psyllium-husk-assisted ZnO sample is attributed to large surface area of carbon material from the psyllium husk and the synergetic effect between the incorporated carbon and ZnO itself. Based on the performance of the hybrid material, it is safe to say that psyllium husk has high potential for use where surface roughness, morphology alteration, and defects in the crystal structure are vital for the enhancing the functionality of a nanostructured material. The observed performance of ZnO in the presence of psyllium husk provides evidence for the fabrication of a low cost and efficient photocatalyst for the wastewater treatment problems

Mn3O4@ZnO Hybrid Material: An Excellent Photocatalyst for the Degradation of Synthetic Dyes including Methylene Blue, Methyl Orange and Malachite Green

In this study, we synthesized hybrid systems based on manganese oxide@zinc oxide (Mn3O4@ZnO), using sol gel and hydrothermal methods. The hybrid materials exhibited hierarchical morphologies and structures characterized by the hexagonal phase of ZnO and the tetragonal phase of Mn3O4. The hybrid materials were tested for degradation of methylene blue (MB), methyl orange (MO), and malachite green (MG) under ultraviolet (UV) light illumination. The aim of this work was to observe the effect of various amounts of Mn3O4 in enhancing the photocatalytic properties of ZnO-based hybrid structures towards the degradation of MB, MO and MG. The ZnO photocatalyst showed better performance with an increasing amount of Mn3O4, and the degradation efficiency for the hybrid material containing the maximum amount of Mn3O4 was found to be 94.59%, 89.99%, and 97.40% for MB, MO and MG, respectively. The improvement in the performance of hybrid materials can be attributed to the high charge separation rate of electron-hole pairs, the co-catalytic role, the large number of catalytic sites, and the synergy for the production of high quantities of oxidizing radicals. The performance obtained from the various Mn3O4@ZnO hybrid materials suggest that Mn3O4 can be considered an effective co-catalyst for a wide range of photocatalytic materials such as titanium dioxide, tin oxide, and carbon-based materials, in developing practical hybrid photocatalysts for the degradation of dyes and for wastewater treatment