Linear and nonlinear tails II: exact decay rates in spherical symmetry

We derive the exact late-time asymptotics for small spherically symmetric solutions of nonlinear wave equations with a potential. The dominant tail is shown to result from the competition between linear and nonlinear effects.Comment: 17 pages, 3 figures, 2 table

Environmental and socio-economic determinants of infant mortality in Poland : an ecological study

BACKGROUND: Health status of infants is related to the general state of health of women of child-bearing age; however, women's occupational environment and socio-economic conditions also seem to play an important role. The aim of the present ecological study was to assess the relationship between occupational environment, industrial pollution, socio-economic status and infant mortality in Poland. METHODS: Data on infant mortality and environmental and socio-economic characteristics for the 66 sub-regions of Poland for the years 2005–2011 were used in the analysis. Factor analysis was used to extract the most important factors explaining total variance among the 23 studied exposures. Generalized Estimating Equations model was used to evaluate the link between infant mortality and the studied extracted factors. RESULTS: Marked variation for infant mortality and the characteristics of industrialization was observed among the 66 sub-regions of Poland. Four extracted factors: “poor working environment”, “urbanization and employment in the service sector”, “industrial pollution”, “economic wealth” accounted for 77.3 % of cumulative variance between the studied exposures. In the multivariate regression analysis, an increase in factor “poor working environment” of 1 SD was related to an increase in infant mortality of 40 (95 % CI: 28–53) per 100,000 live births. Additionally, an increase in factor “industrial pollution” of 1 SD was associated with an increase in infant mortality of 16 (95 % CI: 2–30) per 100,000 live births. The factors “urbanization and employment in the service sector” and “economic wealth” were not significantly related to infant mortality. CONCLUSION: The study findings suggested that, at the population level, infant mortality was associated with an industrial environment. Strategies to improve working conditions and reduce industrial pollution might contribute to a reduction in infant mortality in Poland. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12940-015-0048-1) contains supplementary material, which is available to authorized users

Study on changing patterns of reproductive behaviours due to maternal features and place of residence in Poland during 1995-2014

Introduction The sharp decline in the total fertility rate in Poland coincided with broader socio-economic changes, which resulted in its reduction to the lowest level observed among the countries of Central and Eastern Europe. Objective. The aim of the study was to investigate and evaluate the changing patterns of reproductive behaviour in rural and urban areas, depending on the demographic and socio-economic features in Poland. Material and Methods Information about live births in Poland in the years 1995–2014 were obtained from the Central Statistical Office. Registered cases of live births in rural and urban areas were analyzed considering the maternal features (age, marital status, main source of income). To evaluate the changes in fertility and comparisons between rural and urban areas, Joinpoint Regresssion was used. Results In 1995–2014, a shift in the age of highest fertility from 20–24 years to 25–29 years was observed. This occurred at the same time as a reduction in the fertility rate per 1,000 women aged 15–29 years, more pronounced in rural areas (95.8 to 60.0) than in urban areas (63.4 to 51.5), while in women aged 30–49 years, a faster increase in fertility was observed in urban areas (16.4 to 32.0) than in rural areas (27.5–29.2). Fertility trends between rural and urban areas differed significantly. A significant increase in live births for employed mothers was shown mainly in 2005–2009; later, the growth rate in rural areas was slower and in urban areas the growth trend stopped. Conclusions The postponement of births and reduction of fertility in women aged 15–29 requires active measures aimed at creating favourable conditions for achieving economic independence for the younger generation, as well as combining work with raising children, especially in rural areas. Abbreviations APC – annual percentage change; AAPC – average annual percentage change; CSO – Central Statistical Office; TFR – total fertility rat

Social costs of loss in productivity-related absenteeism in Poland

Objectives: The aim of this study was to estimate indirect costs associated with losses in productivity due to sickness absence among registered workers in Poland. Material and Methods: Data on sick leave durations in 2013 was obtained from the Social Insurance Institution (SII) (Zakład Ubezpieczeń Społecznych – ZUS). Based on the number of assumptions, this data was used for calculating absence durations. The costs of lost productivity were estimated on the basis of the measure of gross value added. Results: Estimated losses in productivity due to absenteeism in 2013 together accounted for 4.33% of gross domestic product (GDP) (17.09 billion euro). In the female population, the total value of losses amounted to 9.66 billion euro, but excluding the costs of pregnancy, childbirth, and puerperium (2.96 billion euro), it was 6.7 billion euro. In the male population, the loss amounted to 7.43 billion euro. The highest overall costs of sickness absence based on age were found in the age group of 30–39 years (5.14 billion euro, including pregnancy, childbirth, and puerperium – 1.474 billion euro; respiratory diseases – 0.632 billion euro, injuries and poisonings – 0.62 billion euro). In the group of people aged > 40 years, the highest cost was generated by bone-muscular diseases (1.553 billion euro) and injuries and poisoning (1.251 billion euro). Higher losses in the productivity of women in addition to pregnancy, childbirth, and puerperium were due to mental and behavioral disorders (0.71 billion euro), diseases of the genitourinary system (0.38 billion euro), and neoplasms (0.35 billion euro). At the same time, in men, compared to women, we observed higher losses due to injuries and poisoning (1.65 billion euro), and diseases of musculoskeletal (1.26 billion euro), nervous (0.79 billion euro), circulatory (0.65 billion euro), and digestive (0.41 billion euro) systems. Conclusions: Improvement and further development of effective strategies for prevention of complications of pregnancy and chronic diseases in the workplace are necessary. Policies aimed at reduction of sickness absence could potentially increase prosperity and the socioeconomic situation in Poland. Int J Occup Med Environ Health 2017;30(6):917–93

Inequalities in mortality of infants under one year of age according to foetal causes and maternal age in rural and urban areas in Poland, 2004-2013

Introduction. European countries are characterized by low mortality during the infancy period compared to other areas of the world. However, there are significant disparities in the state of infant health which are related to socio-economic conditions and place of residence. Objective. Analysis of mortality in Poland from foetal and maternal causes (length of gestation, birth weight, maternal age) in the neonatal and post-neonatal period depending on place of residence (rural and urban areas) in 2004–2013. Materials and method. Data on mortality during the neonatal and infancy period in 2004–2013 was obtained from the Central Statistical Office. Diagnosed cases of deaths in rural and urban areas were analyzed, taking into account the causes of death according to ICD-10, the duration of pregnancy in weeks, birth weight, and maternal age. Trend analysis and comparison of mortality between rural and urban areas were performed using the Poisson regression model. Results. In rural areas, neonatal and post-neonatal death rates due to congenital malformations were siginificantly higher than in urban areas. The mortality rate was also higher in rural areas in children born to women aged 20–34 years, and children born after 37 weeks gestation with low birth weight. In the cities, higher post-neonatal mortality was due to respiratory diseases, and in children born after 37 weeks gestation to mothers under the age of 20 years. A decrease in the mortality of newborns and infants was observed, but in rural areas neonatal mortality decreased significantly more slowly. Conclusions. The results indicate the need to intensify programmes aimed at improving access to prenatal and maternity care, especially among women in rural areas

Late-time tails of a self-gravitating massless scalar field, revisited

We discuss the nonlinear origin of the power-law tail in the long-time evolution of a spherically symmetric self-gravitating massless scalar field in even-dimensional spacetimes. Using third-order perturbation method, we derive explicit expressions for the tail (the decay rate and the amplitude) for solutions starting from small initial data and we verify this prediction via numerical integration of the Einstein-scalar field equations in four and six dimensions. Our results show that the coincidence of decay rates of linear and nonlinear tails in four dimensions (which has misguided some tail hunters in the past) is in a sense accidental and does not hold in higher dimensions.Comment: 10 pages, 6 figures, one reference added, updated to conform with published versio

Protective Effect of Melatonin on Acute Pancreatitis

Melatonin, a product of the pineal gland, is released from the gut mucosa in response to food ingestion. Specific receptors for melatonin have been detected in many gastrointestinal tissues including the pancreas. Melatonin as well as its precursor, L-tryptophan, attenuates the severity of acute pancreatitis and protects the pancreatic tissue from the damage caused by acute inflammation. The beneficial effect of melatonin on acute pancreatitis, which has been reported in many experimental studies and supported by clinical observations, is related to: (1) enhancement of antioxidant defense of the pancreatic tissue, through direct scavenging of toxic radical oxygen (ROS) and nitrogen (RNS) species, (2) preservation of the activity of antioxidant enzymes; such as superoxide dismutase (SOD), catalase (CAT), or glutathione peroxidase (GPx), (3) the decline of pro-inflammatory cytokine tumor necrosis α (TNFα) production, accompanied by stimulation of an anti-inflammatory IL-10, (4) improvement of pancreatic blood flow and decrease of neutrophil infiltration, (5) reduction of apoptosis and necrosis in the inflamed pancreatic tissue, (6) increased production of chaperon protein (HSP60), and (7) promotion of regenerative process in the pancreas. Conclusion. Endogenous melatonin produced from L-tryptophan could be one of the native mechanisms protecting the pancreas from acute damage and accelerating regeneration of this gland. The beneficial effects of melatonin shown in experimental studies suggest that melatonin ought to be employed in the clinical trials as a supportive therapy in acute pancreatitis and could be used in people at high risk for acute pancreatitis to prevent the development of pancreatic inflammation

Saddle-point dynamics of a Yang-Mills field on the exterior Schwarzschild spacetime

We consider the Cauchy problem for a spherically symmetric SU(2) Yang-Mills field propagating outside the Schwarzschild black hole. Although solutions starting from smooth finite energy initial data remain smooth for all times, not all of them scatter since there are non-generic solutions which asymptotically tend to unstable static solutions. We show that a static solution with one unstable mode appears as an intermediate attractor in the evolution of initial data near a border between basins of attraction of two different vacuum states. We study the saddle-point dynamics near this attractor, in particular we identify the universal phases of evolution: the ringdown approach, the exponential departure, and the eventual decay to one of the vacuum states.Comment: 15 pages, 5 figure

Profiles of phenotype resistance to antibiotic other than β-lactams in Klebsiella pneumoniae ESBLs-producers, carrying blaSHV genes

Extended spectrum β-lactamases production is one of the most common mechanism of resistance to extendedspectrum β-lactam antibiotics is increasing worldwide. Twenty five strains of Klebsiella pneumoniae isolated from clinicalspecimens were tested. Based on the phenotypic confirmatory test all these strains were defined as ESBL producers namedESBL(+). The plasmid DNA from each strains was used to investigate the presence of blaSHV genes responsible for extendedspectrum β-lactamases production. Moreover, susceptibility of these strains to antibiotic other than β-lactams in was tested