11 research outputs found
ΠΠ΅ΡΠΎΠ΄ΠΈΠΊΠ° ΠΏΡΠΎΠ΅ΠΊΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΡΠ΅Ρ Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΡ Π΅ΠΌΠ° ΠΏΠΎΠ²ΡΠΎΡΠ½ΠΎΠΉ Π»ΠΈΠΊΠ²ΠΈΠ΄Π°ΡΠΈΠΈ Π½Π°ΠΊΠ»ΠΎΠ½Π½ΡΡ ΡΡΠ²ΠΎΠ»ΠΎΠ² Π·Π°ΠΊΡΡΡΡΡ ΡΠ³ΠΎΠ»ΡΠ½ΡΡ ΡΠ°Ρ Ρ
ΠΠ° ΠΎΡΠ½ΠΎΠ²Π΅ Π°Π½Π°Π»ΠΈΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½Ρ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠ°
ΠΏΡΠΎΠ΅ΠΊΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΡ
Π΅ΠΌΠ° ΠΏΠΎΠ²ΡΠΎΡΠ½ΠΎΠΉ Π»ΠΈΠΊΠ²ΠΈΠ΄Π°ΡΠΈΠΈ Π½Π°ΠΊΠ»ΠΎΠ½Π½ΡΡ
Π²ΡΡΠ°Π±ΠΎΡΠΎΠΊ
Π·Π°ΠΊΡΡΡΡΡ
ΡΠ°Ρ
Ρ ΡΠΏΠΎΡΠΎΠ±ΠΎΠΌ ΡΠ°ΠΌΠΏΠΎΠ½Π°ΠΆΠ° ΡΠ΅ΡΡΡΡΠΎΡΠ±Π΅ΡΠ΅Π³Π°ΡΡΠΈΠΌΠΈ Π±Π΅Π·ΡΡΠ°Π΄ΠΎΡΠ½ΡΠΌΠΈ ΡΠΌΠ΅ΡΡΠΌΠΈ.
Π’Π΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΡΡ Π³Π΅ΠΎΠΌΠ΅Ρ
Π°Π½ΠΈΡΠ΅ΡΠΊΡΡ ΡΡΡΠΎΠΉΡΠΈΠ²ΠΎΡΡΡ ΠΏΠΎΡΠΎΠ΄Π½ΠΎΠ³ΠΎ ΠΌΠ°ΡΡΠΈΠ²Π°
Long-term health status and systemic complaints following implant-based, autologous, or tertiary breast reconstruction
Reply to the Letter to the Editor by Wade et al. "The importance of the Unit of Analysis". Commentary on: Beugels J et al. Complications in unilateral versus bilateral deep inferior epigastric artery perforator flap breast reconstructions: A multicentre study
Improving the quality of life of patients with breast cancer-related lymphoedema by lymphaticovenous anastomosis (LVA):study protocol of a multicentre randomised controlled trial
Contains fulltext :
219858.pdf (publisher's version ) (Open Access)INTRODUCTION: Early breast cancer detection and advancements in treatment options have resulted in an increase of breast cancer survivors. An increasing number of women are living with the long-term effects of breast cancer treatment, making the quality of survivorship an increasingly important goal. Breast cancer-related lymphoedema (BCRL) is one of the most underestimated complications of breast cancer treatment with a reported incidence of 20%. A microsurgical technique called lymphaticovenous anastomosis (LVA) might be a promising treatment modality for patients with BCRL. The main objective is to assess whether LVA is more effective than the current standard therapy (conservative treatment) in terms of improvement in quality of life and weather it is cost-effective. METHODS AND ANALYSIS: A multicentre, randomised controlled trial, carried out in two academic and two community hospitals in the Netherlands. The study population includes 120 women over the age of 18 who have undergone treatment for breast cancer including axillary treatment (sentinel lymph node biopsy or axillary lymph node dissection) and/or axillary radiotherapy, presenting with an early stage lymphoedema of the arm, viable lymphatic vessels and received at least 3 months conservative treatment. Sixty participants will undergo the LVA operation and the other sixty will continue their regular conservative treatment, both with a follow-up of 24 months. The primary outcome is the health-related quality of life. Secondary outcomes are societal costs, quality adjusted life years, cost-effectiveness ratio, discontinuation rate of conservative treatment and excess limb volume. ETHICS AND DISSEMINATION: The study was approved by the Ethics Committee of Maastricht University Medical Center (METC) on 19 December 2018 (NL67059.068.18). The results of this study will be disseminated in presentations at academic conferences, publications in peer-reviewed journals and other news media. TRIAL REGISTRATION NUMBER: NCT02790021; Pre-results