Constraints on the binary black hole hypothesis for system LB-1

At about 70 solar masses, the recently-discovered dark object orbited by a B-type star in the system LB-1 is difficult to understand as the end point of standard stellar evolution, except as a binary black hole (BBH). LB-1 shows a strong, broad H-alpha emission line that is best attributed to a gaseous disk surrounding the dark mass. We use the observed H-alpha line shape, particularly its wing extension, to constrain the inner radius of the disk and thereby the separation of a putative BBH. The hypothesis of a current BBH is effectively ruled out on the grounds that its merger time must be a small fraction of the current age of the B star. The hypothesis of a previous BBH that merged to create the current dark mass is also effectively ruled out by the low orbital eccentricity, due to the combination of mass loss and kick resulted from gravitational wave emission in any past merger. We conclude that the current dark mass is a single black hole produced by the highly mass-conserving, monolithic collapse of a massive star

USDA ARS Corn Breeding

The United States Department of AgricultureAgricultural Research Service (USDA ARS) evaluated 5,412 experimental corn research plots at the Southeast Research Farm in 2010 representing three research projects within USDA ARS: Germplasm Enhancement of Maize (GEM). The objective of the GEM project is to increase the diversity of U.S. maize germplasm utilized by producers, global end-users, and consumers. The mission is accomplished though a collaborative effort between USDA-ARS and both public and private research scientists. Genetic Analysis of Selection Response in Maize Populations. The objective of this project is to develop more efficient strategies to increase maize production. The primary emphasis is on understanding the genetics of adaptation to high plant density. Breeding High-Quality Corn for LowInput and Organic Farming Systems. The primary objective of this project is to develop germplasm for low-input and organic farming systems through conventional breeding

Faint dwarfs as a test of DM models: WDM vs. CDM

We use high resolution Hydro$+$N-Body cosmological simulations to compare the assembly and evolution of a small field dwarf (stellar mass ~ 10$^{6-7}$ M$\odot$, total mass 10$^{10}$ M$\odot$ in $\Lambda$ dominated CDM and 2keV WDM cosmologies. We find that star formation (SF) in the WDM model is reduced and delayed by 1-2 Gyr relative to the CDM model, independently of the details of SF and feedback. Independent of the DM model, but proportionally to the SF efficiency, gas outflows lower the central mass density through `dynamical heating', such that all realizations have circular velocities $<$ 20kms at 500$~$pc, in agreement with local kinematic constraints. As a result of dynamical heating, older stars are less centrally concentrated than younger stars, similar to stellar population gradients observed in nearby dwarf galaxies. Introducing an important diagnostic of SF and feedback models, we translate our simulations into artificial color-magnitude diagrams and star formation histories in order to directly compare to available observations. The simulated galaxies formed most of their stars in many $\sim$10 Myr long bursts. The CDM galaxy has a global SFH, HI abundance and Fe/H and alpha-elements distribution well matched to current observations of dwarf galaxies. These results highlight the importance of directly including `baryon physics' in simulations when 1) comparing predictions of galaxy formation models with the kinematics and number density of local dwarf galaxies and 2) differentiating between CDM and non-standard models with different DM or power spectra.Comment: 13 pages including Appendix on Color Magnitude Diagrams. Accepted by MNRAS. Added one plot and details on ChaNGa implementation. Reduced number of citations after editorial reques

Two Exoplanets Discovered at Keck Observatory

We present two exoplanets detected at Keck Observatory. HD 179079 is a G5 subgiant that hosts a hot Neptune planet with Msini = 27.5 M_earth in a 14.48 d, low-eccentricity orbit. The stellar reflex velocity induced by this planet has a semiamplitude of K = 6.6 m/s. HD 73534 is a G5 subgiant with a Jupiter-like planet of Msini = 1.1 M_jup and K = 16 m/s in a nearly circular 4.85 yr orbit. Both stars are chromospherically inactive and metal-rich. We discuss a known, classical bias in measuring eccentricities for orbits with velocity semiamplitudes, K, comparable to the radial velocity uncertainties. For exoplanets with periods longer than 10 days, the observed exoplanet eccentricity distribution is nearly flat for large amplitude systems (K > 80 m/s), but rises linearly toward low eccentricity for lower amplitude systems (K > 20 m/s).Comment: 8 figures, 6 tables, accepted, Ap

Deep roots and soil structure

In this opinion article we examine the relationship between penetrometer resistance and soil depth in the field. Assuming that root growth is inhibited at penetrometer resistances > 2.5 MPa, we conclude that in most circumstances the increases in penetrometer resistance with depth are sufficiently great to confine most deep roots to elongating in existing structural pores. We suggest that deep rooting is more likely related to the interaction between root architecture and soil structure than it is to the ability of a root to deform strong soil. Although the ability of roots to deform strong soil is an important trait, we propose it is more closely related to root exploration of surface layers than deep rooting

Effect of the Ocular Microenvironment in Regulating Corneal Dendritic Cell Maturation

Objective To determine whether the ocular anterior segment (aqueous humor and cornea) actively inhibits dendritic cell (DC) maturation. Methods Dendritic cells were injected into syngeneic corneas or conjunctivae, and their surface major histocompatibility complex class II expression in response to the local milieu was assessed using confocal microscopy. Immature DCs were cocultured with corneal supernatant or with aqueous humor to evaluate their regulation of DC phenotypic and functional maturity. Results In contrast to conjunctivally injected DCs, DCs injected into the cornea resisted up-regulation in expression of surface major histocompatibility complex class II. Corneal supernatant–treated and aqueous humor–treated DCs retained their immaturity, as reflected by high antigen uptake but low costimulatory molecule (CD80 and CD86) expression and poor T-cell stimulation. Anti–transforming growth factor β2 treatment of aqueous humor and of corneal supernatant led to complete and partial blockade of their inhibition of DC maturation, respectively. However, α-melanocyte–stimulating hormone and calcitonin gene-related peptide had no demonstrable effect on DC maturation. Conclusion Cornea and aqueous humor, principally through transforming growth factor β2, promote generation of phenotypically and functionally immature DCs. Clinical Relevance Our results indicate that relative immune quiescence in the cornea and in the anterior segment is actively maintained in part by the inhibitory effect of transforming growth factor β2 on resident DCs and by their suppression of T-cell–mediated immune and inflammatory responses

Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis

Many epithelial compartments undergo constitutive renewal in homeostasis but activate unique regenerative responses following injury. The clear corneal epithelium is crucial for vision and is renewed from limbal stem cells (LSCs). Using single-cell RNA sequencing, we profiled the mouse corneal epithelium in homeostasis, aging, diabetes, and dry eye disease (DED), where tear deficiency predisposes the cornea to recurrent injury. In homeostasis, we capture the transcriptional states that accomplish continuous tissue turnover. We leverage our dataset to identify candidate genes and gene networks that characterize key stages across homeostatic renewal, including markers for LSCs. In aging and diabetes, there were only mild changes with \u3c15 dysregulated genes. The constitutive cell types that accomplish homeostatic renewal were conserved in DED but were associated with activation of cell states that comprise adaptive regeneration. We provide global markers that distinguish cell types in homeostatic renewal vs. adaptive regeneration and markers that specifically define DED-elicited proliferating and differentiating cell types. We validate that expression of SPARC, a marker of adaptive regeneration, is also induced in corneal epithelial wound healing and accelerates wound closure in a corneal epithelial cell scratch assay. Finally, we propose a classification system for LSC markers based on their expression fidelity in homeostasis and disease. This transcriptional dissection uncovers the dramatically altered transcriptional landscape of the corneal epithelium in DED, providing a framework and atlas for future study of these ocular surface stem cells in health and disease