Measuring charged current neutrino interactions in the electromagnetic calorimeters of the ND280 detector

This thesis presents a study of neutrino interactions within the electromagnetic calorimeters (ECals) of the Tokai-to-Kamioka (T2K) off -axis near detector (ND280), using data collected from T2K Run II and Run III. Neutrino oscillation physics is a rapidly advancing field, with the recent discovery of non-zero [Symbol appears here. To view, please open pdf attachment]13 allowing the possibility of measuring CP-violation in the lepton sector. The current neutrino beam experiments must make precise measurements of the oscillation parameters and to do this require an improved understanding of neutrino interactions, which can only come through better measurements of neutrino cross-sections. This thesis describes the development of a neutrino event selection using a boosted decision tree multi-variate analysis to separate interactions within the ND280 ECals from entering backgrounds. This is then used to provide a selection of neutrino event samples from each ECal module, which are inputs to a X2 fit that is used to extract the [Symbols appears here. To view, please open pdf attachment] charged current inclusive cross-section, which was found to be [Mathematical equation appears here. To view, please open pdf attachment].Open Acces

Mississippi Teacher Corps Trains Record Class

More than 50 percent of new recruits to teach math or scienc

Visor Scratch Repair and Prevention

Severe eye injuries occur in 30 percent of demining accidents. Visors are known to be effective personal protective equipment when worn properly, but deminers often lift or remove their visors because scratches, glare or fog make them hard to see through, or because they are hot, heavy and uncomfortable to wear. Addressing each of these specific design problems could increase visor use and prevent a significant number of debilitating injuries. This paper presents methods for preventing and eliminating scratches on demining visors

Antibody-based detection of protein phosphorylation status to track the efficacy of novel therapies using nanogram protein quantities from stem cells and cell lines

This protocol describes a highly reproducible antibody-based method that provides protein level and phosphorylation status information from nanogram quantities of protein cell lysate. Nanocapillary isoelectric focusing (cIEF) combines with UV-activated linking chemistry to detect changes in phosphorylation status. As an example application, we describe how to detect changes in response to tyrosine kinase inhibitors (TKIs) in the phosphorylation status of the adaptor protein ​CrkL, a major substrate of the oncogenic tyrosine kinase ​BCR-​ABL in chronic myeloid leukemia (CML), using highly enriched CML stem cells and mature cell populations in vitro. This protocol provides a 2.5 pg/nl limit of protein detection (<0.2% of a stem cell sample containing <104 cells). Additional assays are described for phosphorylated tyrosine 207 (pTyr207)-​CrkL and the protein tyrosine phosphatase ​PTPRC/​CD45; these assays were developed using this protocol and applied to CML patient samples. This method is of high throughput, and it can act as a screen for in vitro cancer stem cell response to drugs and novel agents

A new VLA/e-MERLIN limit on central images in the gravitational lens system CLASS B1030+074

We present new VLA 22-GHz and e-MERLIN 5-GHz observations of CLASS B1030+074, a two-image strong gravitational lens system whose background source is a compact flat-spectrum radio quasar. In such systems we expect a third image of the background source to form close to the centre of the lensing galaxy. The existence and brightness of such images is important for investigation of the central mass distributions of lensing galaxies, but only one secure detection has been made so far in a galaxy-scale lens system. The noise levels achieved in our new B1030+074 images reach 3 microJy/beam and represent an improvement in central image constraints of nearly an order of magnitude over previous work, with correspondingly better resulting limits on the shape of the central mass profile of the lensing galaxy. Simple models with an isothermal outer power law slope now require either the influence of a central supermassive black hole, or an inner power law slope very close to isothermal, in order to suppress the central image below our detection limit. Using the central mass profiles inferred from light distributions in Virgo galaxies, moved to z=0.5, and matching to the observed Einstein radius, we now find that 45% of such mass profiles should give observable central images, 10% should give central images with a flux density still below our limit, and the remaining systems have extreme demagnification produced by the central SMBH. Further observations of similar objects will therefore allow proper statistical constraints to be placed on the central properties of elliptical galaxies at high redshift.Comment: Accepted by Monthly Notices of the Royal Astronomical Society. 16 pages, 8 figure