Disaster resilience and children: managing food security in Zimbabwe's Binga District

The growing recognition of the vulnerability of children to disasters has added a new impetus to the concept of their involvement in disaster risk reduction programs. Involving children in disaster risk reduction is among those aspects promoted in the Hyogo Framework for Action 2005–2015 to enhance the resilience of disaster-affected communities. This article presents the results from a research study which investigated the involvement of children in disaster risk reduction programs in Binga District, Zimbabwe, focusing on food security. The results suggest that children are an invaluable part of human agency in disaster contexts, especially in view of increasing numbers of children orphaned by HIV and AIDS. Yet their involvement is still contested. Unless family and cultural pressures imposed on children are recognized and managed in disaster risk programming, the potential of children’s involvement is likely to be missed in building disaster-resilient communities

The political economy of health services provision and access in Brazil

The authors examine the impact of local politics and government structure on the allocation of publicly subsidized (SUS) health services across municipios (counties) in Brazil, and on the probability that uninsured individuals who require medical attention actually receive access to those health services. Using data from the 1998 PNAD survey they demonstrate that higher per capita levels of SUS doctors, nurses, and clinic rooms increase the probability that an uninsured individual gains access to health services when he, or she seeks it. The authors find that an increase in income inequality, an increase in the percentage of the population that votes, and an increase in the percentage of votes going to left-leaning candidates are each associated with higher levels of public health services. The per capita provision of doctors, nurses, and clinics is also greater in counties with a popular local leader, and in counties where the county mayor and state governor are politically aligned. Administrative decentralization of health services to the county decreases provision levels, and reduces access to services by the uninsured, unless it is accompanied by good local governance.Health Systems Development&Reform,Health Monitoring&Evaluation,Public Health Promotion,Regional Rural Development,Gender and Health,Health Economics&Finance,Health Monitoring&Evaluation,Health Systems Development&Reform,Regional Rural Development,Gender and Health

Residential child care qualifications audit 2007

In recent years there has been a drive to develop a fully qualified residential child care sector in Scotland. In 2003 the Scottish Social Services Council (SSSC) announced the baseline qualifications for residential child care staff and set down a target for attaining it. This qualifications framework was subsequently reviewed and expanded in 2004. The Scottish Institute for Residential Child Care (SIRCC), commissioned by the Scottish Executive, has previously undertaken two inquiries into the qualification levels of the residential child care workforce in Scotland. The first Qualifications Audit (Frondigoun, Maclean, Hosie & Kendrick, 2002) was undertaken before the SSSC’s initial qualification framework was known and the second (Hunter, Hosie, Davidson & Kendrick, 2004) was based on it. The previous qualifications audit (Hunter et al., 2004) reported that 18% of residential child care staff were fully qualified in accordance with the SSSC’s qualification criteria (SSSC, 2004). The report forecast that the number of fully qualified staff would rise to 29.1% if all qualifications being undertaken were achieved. The purpose of this current audit is to determine whether levels of qualified staff have risen and to identify qualification trends throughout the residential child care sector in Scotland

Disaster education in the UK

The seminar series brought together emergency management specialists and educationalists to explore how disaster management knowledge, innovation and education can contribute to building a culture of safety and resilience in the UK. The series was primarily focussed on ways of understanding UK disaster reduction contexts, though informed by contributions from other parts of the world. The strengthening of debate on practical and policy developments for disaster education helped exchange experiences and ideas about dealing with changing hazards and vulnerabilities. This contributed to wider and strengthened interest in disaster risk reduction engagement through associated educational needs. The series analysed conceptual, practical and policy issues surrounding UK disaster education. Institutional partners were The universities of Northumbria (lead), Glamorgan, UCL and Kyoto served as partners with significant inputs from practice institutions, including in hosting of seminars. This facilitated a rich mix of learning cultures from within and without the academy for open debate and awareness building regards learning and education in disaster reduction. There are consequent developments for further activities beyond the life of this grant, such as ongoing additional conference sessions on disaster education, an EU project, and a DFID funded disaster education and community resilience programme in Zimbabwe and Bangladesh. These also feed back into the UK context. The series exposed a deeply held interest in disaster education from within the UK emergency management sector. Key conclusions were the need to develop in depth grounded learning processes, integrated institutional development and mixed qualitative and quantitative tools for the job

The responses of Tribolium castaneum to wheat germ oil and fungal produced volatiles: Presentation

The red flour beetle Tribolium castaneum Herbst (Coleoptera: Tenebrionidae) is a significant pest affecting a wide variety of different stored products around the Globe. Despite its economic impact, there is evidence that the lures currently used in traps to monitor for this species are largely ineffective. Based on the evolutionary history of T. castaneum, and the ecological niche it occupies, the volatiles of wheat germ oil and volatiles produced by grain-associated fungi have the potential to act as attractants for this species. We used electroantennography (EAG) to measure the electrophysiological response elicited by sixty-eight volatile compounds found in wheat germ oil and/or grain-associated fungi in two T. castaneum strains; an established lab population (CTC12 strain) and a recently caught wild population. Many volatile compounds from both sources elicited strong antennal depolarisations, and the responses of both strains were highly correlated. We then tested whether the compounds that triggered the strongest antennal depolarisations also elicited behavioural responses by using Y-tube olfactometer bioassays and identified several compounds attractive to both strains. The discovery of novel compounds that elicit strong EAG signals and behavioural responses could prove useful in the design of improved lures for T. castaneum and other stored product pests. Our future research will identify how effective these attractive volatiles might be when used in combination, and when used under conditions that more closely replicate a stored product environment.The red flour beetle Tribolium castaneum Herbst (Coleoptera: Tenebrionidae) is a significant pest affecting a wide variety of different stored products around the Globe. Despite its economic impact, there is evidence that the lures currently used in traps to monitor for this species are largely ineffective. Based on the evolutionary history of T. castaneum, and the ecological niche it occupies, the volatiles of wheat germ oil and volatiles produced by grain-associated fungi have the potential to act as attractants for this species. We used electroantennography (EAG) to measure the electrophysiological response elicited by sixty-eight volatile compounds found in wheat germ oil and/or grain-associated fungi in two T. castaneum strains; an established lab population (CTC12 strain) and a recently caught wild population. Many volatile compounds from both sources elicited strong antennal depolarisations, and the responses of both strains were highly correlated. We then tested whether the compounds that triggered the strongest antennal depolarisations also elicited behavioural responses by using Y-tube olfactometer bioassays and identified several compounds attractive to both strains. The discovery of novel compounds that elicit strong EAG signals and behavioural responses could prove useful in the design of improved lures for T. castaneum and other stored product pests. Our future research will identify how effective these attractive volatiles might be when used in combination, and when used under conditions that more closely replicate a stored product environment

Captive Breeding Protocols and Their Impact on Genetic Diversity in White-footed Mice (Peromyscus leucopus): Implications for Threatened and Endangered Species

Captive breeding protocols used in zoos often are aimed at increasing population sizes and retaining genetic diversity of endangered species. However, captive breeding causes genetic adaptation to captivity that can lead to an overall decrease in genetic diversity and reduce chances of a successful reintroduction to the wild. In this study, we assess how 3 different breeding protocols—random mating, preferential breeding of individuals with the lowest mean kinship scores, and selection for docility—affect the variability of mitochondrial DNA in white-footed mice (Peromyscus leucopus). We used mice that were captured from the wild but were mated for up to 20 generations using one of the aforementioned breeding protocols. Using animals from generations 0, 6, and 19, as well as the wild source population, we sequenced the mitochondrial D-loop in 2 replicate populations representing each of the 3 breeding protocols. Initial sequences indicate there is genetic variation at this mitochondrial locus, and further sequencing will allow us to quantify the genetic diversity maintained under each breeding protocol. These results will increase our understanding of the decline in genetic diversity due to adaptation to captivity. Thus, our results will have direct relevance for the maintenance and growth of zoo populations of critically endangered species

Anthocyanins inhibit tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity

An increased permeability of the intestinal barrier is proposed as a major event in the pathophysiology of conditions characterized by chronic gut inflammation. This study investigated the capacity of pure anthocyanins (AC), and berry and rice extracts containing different types and amounts of AC, to inhibit tumor necrosis alpha (TNFα)-induced permeabilization of Caco-2 cell monolayers. Caco-2 cells differentiated into intestinal epithelial cell monolayers were incubated in the absence/presence of TNFα, with or without the addition of AC or AC-rich plant extracts (ACRE). AC and ACRE inhibited TNFα-induced loss of monolayer permeability as assessed by changes in transepithelial electrical resistance (TEER) and paracellular transport of FITC-dextran. In the range of concentrations tested (0.25–1 μM), O-glucosides of cyanidin, and delphinidin, but not those of malvidin, peonidin and petunidin protected the monolayer from TNFα-induced decrease of TEER and increase of FITC-dextran permeability. Cyanidin and delphinidin acted by mitigating TNFα-triggered activation of transcription factor NF-κB, and downstream phosphorylation of myosin light chain (MLC). The protective actions of the ACRE on TNFα-induced TEER increase was positively correlated with the sum of cyanidins and delphinidins (r2 = 0.83) content in the ACRE. However, no correlation was observed between TEER and ACRE total AC, malvidin, or peonidin content. Results support a particular capacity of cyanidins and delphinidins in the protection of the intestinal barrier against inflammation-induced permeabilization, in part through the inhibition of the NF-κB pathway.Fil: Cremonini, Eleonora. University of California at Davis; Estados UnidosFil: Mastaloudis, Angela. Nu Skin Enterprises; Estados UnidosFil: Hester, Shelly N.. Nu Skin Enterprises; Estados UnidosFil: Verstraeten, Sandra Viviana. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Biológica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; ArgentinaFil: Anderson, Maureen. University of California at Davis; Estados UnidosFil: Wood, Steven M.. Nu Skin Enterprises; Estados UnidosFil: Waterhouse, Andrew L.. University of California at Davis; Estados UnidosFil: Fraga, César Guillermo. University of California at Davis; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Bioquímica y Medicina Molecular; ArgentinaFil: Oteiza, Patricia Isabel. University of California at Davis; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Identification and Characterization of Epp, the Secreted Processing Protease for the \u3cem\u3eVibrio anguillarum\u3c/em\u3e EmpA Metalloprotease

The zinc metalloprotease EmpA is a virulence factor for the fish pathogen Vibrio anguillarum. Previous studies demonstrated that EmpA is secreted as a 46-kDa proenzyme that is activated extracellularly by the removal of an ∼10-kDa propeptide. We hypothesized that a specific protease is responsible for processing secreted pro-EmpA into mature EmpA. To identify the protease responsible for processing pro-EmpA, a minitransposon mutagenesis (using mini-Tn10Km) clone bank of V. anguillarum was screened for reduced protease activity due to insertions in undescribed genes. One mutant with reduced protease activity was identified. The region containing the mini-Tn10Km was cloned, sequenced, and found to contain epp, an open reading frame encoding a putative protease. Further characterization of epp was done using strain M101, created by single-crossover insertional mutagenesis. Protease activity was absent in M101 cultures even when empA protease activity was induced by salmon gastrointestinal mucus. When the epp mutation was complemented with a wild-type copy of epp (M102), protease activity was restored. Western blot analysis of sterile filtered culture supernatants from wild-type (M93Sm) cells, M101 cells, and M102 cells revealed that only pro-EmpA was present in M101supernatants; both pro-EmpA and mature EmpA were detected in M93Sm and M102 supernatants. When sterile filtered culture supernatants from the empA mutant strain (M99) and M101 were mixed, protease activity was restored. Western blot analysis revealed that pro-EmpA in M101 culture supernatant was processed to mature EmpA only after mixing with M99 culture supernatant. These data show that Epp is the EmpA-processing protease