Additional file 1: Figure S1. of Impact of the estimation equation for GFR on population-based prevalence estimates of kidney dysfunction

Bland-Altman plots for comparison between Full Age Spectrum creatinine equation (FAScre) and the other equations used to estimate GFR among 7001 adults aged 18–79 in Germany 2008–2011 (DEGS1). MDRD: Modification of Diet in Renal Disease study equation; CKD-EPIcre: Chronic Kidney Disease Epidemiology Collaboration creatinine equation; CKD-EPIcys: Chronic Kidney Disease Epidemiology Collaboration cystatin C equation; CKD-EPIcrecys: Chronic Kidney Disease Epidemiology Collaboration creatinine and cystatin C equation; LM: Lund-Malmö equation; FAScre: Full Age Spectrum creatinine equation. Solid, horizontal lines represent the mean difference between the eGFR. Dashed, horizontal lines represent the limit of agreement between the equations. Solid, vertical lines represent the eGFR cut-off value of a decreased kidney function (60 ml/min/1.73m2). (PDF 422 kb

VMJ767761_Supplementary_material – Supplemental material for Life expectancy and comorbidities in patients with hereditary hemorrhagic telangiectasia

<p>Supplemental material, VMJ767761_Supplementary_material for Life expectancy and comorbidities in patients with hereditary hemorrhagic telangiectasia by Freya Droege, Kruthika Thangavelu, Boris A Stuck, Andreas Stang, Stephan Lang and Urban Geisthoff in Vascular Medicine</p

Low socio-economic position is associated with poor social networks and social support: results from the Heinz Nixdorf Recall Study-1

<p><b>Copyright information:</b></p><p>Taken from "Low socio-economic position is associated with poor social networks and social support: results from the Heinz Nixdorf Recall Study"</p><p>http://www.equityhealthj.com/content/7/1/13</p><p>International Journal for Equity in Health 2008;7():13-13.</p><p>Published online 5 May 2008</p><p>PMCID:PMC2424055.</p><p></p

Associations between perceived risk of developing diabetes ^a and putative determinants of diabetes risk perception in persons with prediabetes.

<p>Results from robust poisson regression models (prevalence ratios (PR), 95% confidence intervals): The KORA FF4 study (N = 773).</p

Subjective risk of diabetes by age and school leaving certificate.

<p>Subjective risk of diabetes by age and school leaving certificate.</p

Perceived risk of having undiagnosed diabetes by categories of glucose regulation: The KORA FF4 study.

<p>Perceived risk of having undiagnosed diabetes by categories of glucose regulation: The KORA FF4 study.</p

Perceived risk of developing diabetes in the next years by categories of glucose regulation: The KORA FF4 study.

<p>Perceived risk of developing diabetes in the next years by categories of glucose regulation: The KORA FF4 study.</p

Epidemiology and Prognostic Implications of Coronary Artery Calcium in Asymptomatic Individuals with Prediabetes: A Multi-Cohort Study

Objectives: To describe the epidemiology and prognostic value of the coronary artery calcium (CAC) among individuals with prediabetes. Research Design and Methods: We pooled participants free of clinical ASCVD from 4 prospective cohorts Multi-Ethnic Study of Atherosclerosis (MESA), Heinz-Nixdorf Recall Study (HNR), Framingham Heart Study (FHS) and Jackson Heart Study (JHS). Two definitions were used for prediabetes: inclusive (fasting plasma glucose [FPG] ≥100-<126 mg/dL and hemoglobin A1c [HbA1c] ≥5.7-<6.5%, if available, among participants not taking glucose-lowering medications) and restrictive (FPG ≥110-<126 mg/dL and HbA1c ≥5.7-<6.5%, if available). Results: The study included 13,376 participants (mean age 58 years, 54% women, 57% White, 27% Black). The proportion with CAC≥100 was 17%, 22%, and 37% among those with euglycemia, prediabetes, and diabetes, respectively. Over a median (25th – 75th percentile) follow up time of 14.6 (7.8-16.4) years, individuals with prediabetes and CAC≥100 had higher unadjusted 10-year incidence of ASCVD (13.4%) than the overall group of those with diabetes (10.6%). In adjusted analyses, using the inclusive definition of prediabetes, compared to individuals with euglycemia the hazard ratio (HR) (95% confidence interval) for ASCVD was 0.79 (0.62, 1.01) for prediabetes and CAC=0, 0.70 (0.54, 0.89) for prediabetes and CAC 1-99, 1.54 (1.27, 1.88) for prediabetes and CAC≥100; and 1.64 (1.39, 1.93) for diabetes. Using the restrictive definition, the HR for ASCVD was 1.63 (1.29, 2.06) for prediabetes and CAC≥100. Conclusions: CAC≥100 is frequent among individuals with prediabetes, and identifies a high ASCVD risk subgroup in which the adjusted ASCVD risk is similar to people with diabetes.</p