Gluelump spectrum from Coulomb gauge QCD

We compute the energy spectrum of gluelumps defined as gluonic excitations bound to a localized, static octet source. We are able to reproduce the nontrivial ordering of the spin-parity levels and show how this is related to the non-abelian part of the Coulomb interaction between color charges.Comment: 8 pages, 5 figure

Heavy quarkonium hybrids from Coulomb gauge QCD

Using the non-relativisitc reduction of Coulomb gauge QCD we compute spectrum of the low mass hybrid mesons containing a heavy quark-antiquark pair. The gluon degrees of freedom are treated in the mean field approximation calibrated to the gluelump spectrum. We discuss the role of the non-abelian nature of the QCD Coulomb interaction in the ordering of the spin-parity levels.Comment: 12 pages, 6 figure

The Streptomyces coelicolor small ORF trpM stimulates growth and morphological development and exerts opposite effects on actinorhodin and calcium-dependent antibiotic production

In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many others still deserve further investigations. In this regard, the possible role of many small open reading frames (smORFs) in actinomycete morpho-physiological differentiation is still elusive. In Streptomyces coelicolor, inactivation of the smORF trpM (SCO2038) – whose product modulates L-tryptophan biosynthesis – impairs production of antibiotics and morphological differentiation. Indeed, it was demonstrated that TrpM is able to interact with PepA (SCO2179), a putative cytosol aminopeptidase playing a key role in antibiotic production and sporulation. In this work, a S. coelicolor trpM knock-in (Sco-trpMKI) mutant strain was generated by cloning trpM into overexpressing vector to further investigate the role of trpM in actinomycete growth and morpho-physiological differentiation. Results highlighted that trpM: (i) stimulates growth and actinorhodin (ACT) production; (ii) decreases calcium-dependent antibiotic (CDA) production; (iii) has no effect on undecylprodigiosin production. Metabolic pathways influenced by trpM knock- in were investigated by combining two-difference in gel electrophoresis/nanoliquid chromatography coupled to electrospray linear ion trap tandem mass spectrometry (2D- DIGE/nanoLC-ESI-LIT-MS/MS) and by LC-ESI-MS/MS procedures, respectively. These analyses demonstrated that over-expression of trpM causes an over-representation of factors involved in protein synthesis and nucleotide metabolism as well as a down-representation of proteins involved in central carbon and amino acid metabolism. At the metabolic level, this corresponded to a differential accumulation pattern of different amino acids – including aromatic ones but tryptophan – and central carbon intermediates. PepA was also down-represented in Sco-trpMKI. The latter was produced as recombinant His-tagged protein and was originally proven having the predicted aminopeptidase activity. Altogether, these results highlight the stimulatory effect of trpM in S. coelicolor growth and ACT biosynthesis, which are elicited through the modulation of various metabolic pathways and PepA representation, further confirming the complexity of regulatory networks that control antibiotic production in actinomycetes

Diseño del Edificio Administrativo de la Universidad Privada de Tacna para Mejorar el Confort Espacial del Usuario Tacna, 2019

La presente investigación tiene como objetivo: Proponer el diseño arquitectónico del edificio administrativo para mejorar el confort espacial para los usuarios en la sede rectoral de la Universidad Privada de Tacna. La investigación es de tipo no experimental, con un enfoque cualitativo, la población de estudio fueron los usuarios internos y externos de la Universidad Privada de Tacna, se utilizaron instrumentos de investigación tales como entrevista y ficha de observación según las dimensiones de las variables. Dentro de los resultados de mayor importancia se encontró que la mayoría de usuarios manifiesta disconfort con respecto a la distribución espacial, circulación, accesibilidad, funcionalidad, e iluminación, en base a los resultados mencionados la propuesta del diseño del edificio administrativo de la Universidad Privada de Tacna cumple con las dimensiones del confort espacial según la normativa, premisas de diseño, condicionantes, y determinantes establecidas a lo largo de la investigación, de esta manera se mejorara la problemática identificada, motivo del presente trabajo de investigación, a la vez esta propuesta tendrá un gran impacto en la imagen institucional de la universidad y por ende de la imagen urbana de la ciudad de TacnaTesi

Insurance Fraud Detection: A Statistically-Validated Network Approach

Fraud is a social phenomenon, and fraudsters oftencollaborate with other fraudsters, taking on differentroles. The challenge for insurance companies is toimplement claim assessment and improve frauddetection accuracy. We developed an investigativesystem based on bipartite networks, highlighting therelationships between subjects and accidents or vehi-cles and accidents. We formalize filtering rules throughprobability models and test specific methods to assessthe existence of communities in extensive networksand propose new alert metrics for suspicious struc-tures. We apply the methodology to a real database—the Italian Antifraud Integrated Archive—and compare the results to out‐of‐sample fraud scams underinvestigation by the judicial authoritie

Investigation of Ducted Fuel Injection Implementation in a Retrofitted Light-Duty Diesel Engine through Numerical Simulation

Ducted Fuel Injection (DFI) is a concept of growing interest to abate soot emissions in diesel combustion, based on a small duct within the combustion chamber in front of the injector nozzle. Despite the impressive potential of the DFI has been proven in literature, its application for series production and the complexity for the adaptation of existing compression-ignition (CI) engines need to be extensively investigated. In this context, the aim of this study is to numerically assess the potential of DFI implementation in a CI engine for light-duty applications, highlighting the factors which can limit or facilitate its integration in existing combustion chambers. The numerical model for combustion simulation was based on a 1D/3D-CFD coupled approach relying on a calibrated spray model, extensively validated against experimental data. Once assessed the coupling procedure by comparing the numerical results with experimental in-cylinder pressure and heat release rate data for both low and high load operating conditions, the duct impact was investigated introducing it in the computational domain. It was observed that DFI did not yield any significant advantage to engine-out soot emissions and fuel consumption with the existing combustion system. Although the soot formation was generally reduced, the soot oxidation process was partially inhibited by the duct adoption maintaining fixed the engine calibration, suggesting the need for complete optimization of the combustion system design. On the other hand, a preliminary variation of engine calibration highlighted several beneficial trends for DFI, whose operation improved with a simplified injection strategy. Present numerical results indicate that DFI retrofit solutions without specific optimization of the combustion system design do not guarantee soot reduction. Nevertheless, wide room for improvement remains in terms of DFI-targeted combustion chamber design and engine calibration towards the complete success of this technology for soot-free CI engines

Synergetic Application of Zero-, One-, and Three-Dimensional Computational Fluid Dynamics Approaches for Hydrogen-Fuelled Spark Ignition Engine Simulation

Nowadays hydrogen, especially if derived from biomass or produced by renewable power, is rising as a key energy solution to shift the mobility of the future toward a low-emission scenario. It is well known that hydrogen can be used with both internal combustion engines (ICEs) and fuel cells (FCs); however, hydrogen-fuelled ICE represents a robust and cost-efficient option to be quickly implemented under the current production infrastructure. In this framework, this article focuses on the conversion of a state-of-the-art 3.0L diesel engine in a hydrogen-fuelled Spark Ignition (SI) one. To preliminarily evaluate the potential of the converted ICE, a proper simulation methodology was defined combining zero-, one-, and three-dimensional (0D/1D/3D) Computational Fluid Dynamics (CFD) approaches. First of all, a detailed kinetic scheme was selected for both hydrogen combustion and Nitrogen Oxides (NOx) emission predictions in a 3D-CFD environment. Afterward, to bring the analysis to a system-level approach, a 1D-CFD predictive combustion model was firstly optimized by implementing a specific laminar flame speed correlation and, secondly, calibrated against the 3D-CFD combustion results. The combustion model was then integrated into a complete engine model to assess the potential benefit derived from the wide range of flammability and the high flame speed of hydrogen on a complete engine map, considering NOx formation and knock avoidance as priority parameters to control. Without a specific modification of turbocharger and combustion systems, a power density of 34 kW/L and a maximum brake thermal efficiency (BTE) of about 42% were achieved, thus paving the way for further hardware optimization (e.g., compression ratio reduction, turbocharger optimization, direct injection [DI]) to fully exploit the advantages enabled by hydrogen combustion

Thermolytic reverse electrodialysis heat engine: model development, integration and performance analysis

Salinity gradient heat engines represent an innovative and promising way to convert low-grade heat into electricity by employing salinity gradient technology in a closed-loop configuration. Among the aqueous solutions which can be used as working fluid, ammonium bicarbonate-water solutions appear very promising due to their capability to decompose at low temperature. In this work, an experimentally validated model for a reverse electrodialysis heat engine fed with ammonium bicarbonate-water solutions was developed. The model consists of two validated sub-models purposely integrated, one for the reverse electrodialysis unit and the other for the stripping/absorption regeneration unit. The impact of using current commercial membranes and future enhanced membranes on the efficiency of the system was evaluated, along with the effect of operating and design parameters through sensitivity analyses. Results indicated that exergy efficiency up to 8.5% may be obtained by considering enhanced future membranes and multi-column regeneration units