Manajemen Program Siaran Lokal Aceh TV Dalam Upaya Penyebarluasan Syariat Islam Dan Pelestarian Budaya Lokal

Managing broadcasting management is not easy. Managing the broadcasting business is a difficult and challenging. This research aims to analyze the activity of management and organizational performance ACEH TV television media in an effort to disseminate the Islamic Sharia and Preservation of Local Culture in Aceh. This research is descriptive qualitative. Informants of this research is managing director, program director, executive producer, cameraman / reporter, as well as additional informants Regional Chairman of the Indonesian Broadcasting Commission (KPID) Aceh, Aceh Province Department of Islamic Law, and local media observers. The location of this research is in Banda Aceh, Aceh province. Sampling was done purposively. Data collected through observation, interviews, and documentation. Data were analyzed by analysis of an interactive model of Miles and Huberman. The results showed that the ACEH TV as the medium of television that is broadcasting management ACEH have done according to a local television broadcasting standard. Agenda setting function of mass media performed in the ACEH TV dissemination of Islamic Shariah in Aceh and local culture to influence the people of Aceh to implement Islamic Sharia and also maintain the culture and local wisdom Aceh. It can be seen from all the programs that are aired ACEH TV is a program of local cultural nuances of Islamic law. There are still some shortcomings in running broadcasting broadcasting technology such as lack of equipment that is increasingly sophisticated. The results of image editing is very simple, and some programs presenter still looks stiff when in front of the camera

Additional file 1: of Remodeling adipose tissue through in silico modulation of fat storage for the prevention of type 2 diabetes

Results from every deletion experiment in the article as well as the assignment of gene essentiality for optimal growth from the 6 cell-lines of the two studies used in the validation of the network. (XLSX 54 kb

Additional file 2: of Remodeling adipose tissue through in silico modulation of fat storage for the prevention of type 2 diabetes

R code for the simulation and validation if iTC1390adip. (ZIP 452 kb

Additional file 3: Figure_S1. of Remodeling adipose tissue through in silico modulation of fat storage for the prevention of type 2 diabetes

Graph of the effect of each gene’s deletion on both biomass and lipid droplet production compared to the wild type network when glucose and TAG uptake are restricted. Table_S1.docx. Biomass and lipid droplet constituent with stoichiometry as well as growth media definition. Table_S2.xlsx. List of metabolic tasks used to insure proper network behavior under various circumstances. Table_S3.xlsx. List of fluxes for imports and exports in the network at each time point when optimising for lipid droplet production with restrictions to the values of TAG extraction, glucose uptake and NEFA release to the experimental values from obese and lean subjects. Table_S4.xlsx. List of fluxes for imports and exports in the network at each time point when optimising for acetyl-CoA production with restrictions to the values of TAG extraction, glucose uptake and NEFA release to the experimental values from obese and lean subjects. Table_S5.xlsx. Effect of gene deletion in mouse models for the genes predicted to have an effect on adipocyte hypertrophy. Table_S6.docx. Number of genes having an increased effect on lipid droplet and biomass production in either of the adipose tissues compared to the other. Table_S7.xlsx. List of genes identified as potential targets when restricting the flux of reactions using gene fold differences between subcutaneous and visceral adipose tissues. iTC1390adip.xml and iTC1390adipRaven.xml files containing the iTC1390adip network in SDML and raven formats as described above. (ZIP 911 kb

Effect of aldose reductase inhibitor on PGF_2α release by human primary preadipocytes.

<p>PGF_2α release by subcutaneous and omental preadipocytes treated for 24 h with 1 ng/ml IL-1β in the presence or absence of increasing concentrations (0-20 μM) of ponalrestat. Data are presented as mean ± SEM. Results are expressed as pg/ml*μg protein*24 h (* p≤0.05, n = 7 for all conditions).</p

PGF_2α release by omental and subcutaneous fat cells.

<p>(<b>A</b>) PGF_2α release by subcutaneous and omental primary preadipocytes in response to TNF-α and/or IL-1β (preadipocytes stimulated for 24 h with 1 ng/ml TNF-α, 1 ng/ml IL-1β or both). Results are expressed as pg/ml*μg protein*24 h (n = 14), (<b>B</b>) PGF_2α release by isolated subcutaneous and omental mature adipocytes in response to TNF-α and/or IL-1β (isolated mature adipocytes stimulated for 2 h with 1 ng/ml TNF-α, 1 ng/ml IL-1β or both). Results are expressed as pg/10⁶cells*2 h (n = 12), (<b>C</b>) PGF_2α release by subcutaneous and omental adipose tissue explants in response to TNF-α and/or IL-1β (explants stimulated for 24 h with 1 ng/ml TNF-α, 1 ng/ml IL-1β or both). Results are expressed as pg/ml*mg tissue*24 h. Data are presented as mean ± SEM. p≤0.05 for treatment-by-depot interaction in panel A and p≤0.05 for treatment effect in panels A and C. * p ≤ 0.05.</p

Plasma Lf levels in severely obese subjects.

<p>Correlations were tested between plasma Lf concentrations and <b>(A)</b> BMI, <b>(B)</b> insulin and <b>(C)</b> HOMA-IR in severely obese subjects without T2D. Pearson correlation coefficients of log-transformed variables and <i>P</i> values are shown in the graph (n = 62); <b>(D)</b> Plasma Lf concentrations in severely obese patients according to HOMA-IR tertiles and to the presence of T2D. * <i>P<</i>0.05.</p

PGF_2α release by omental mature adipocytes.

<p>Comparison of (<b>A</b>) omental adipocyte PGF_2α release; (<b>B</b>) subcutaneous adipocyte PGF_2α release; (<b>C</b>) omental <i>AKR1B1</i> mRNA expression; and (<b>D</b>) subcutaneous <i>AKR1B1</i> mRNA expression in women with low or high omental adipocyte PGF_2α release. Data are presented as mean ± SEM. ^† p < 0.10, *p ≤ 0.05, **p ≤ 0.005, *** p ≤ 0.0001. Expression levels relative to <i>ATP5O</i> mRNA expression. OM: omental; SC: Subcutaneous.</p

COX-2 and PGF synthase expression in primary preadipocytes.

<p>Messenger RNA expression and protein levels of COX-2 (<b>A</b> and <b>B</b>, respectively), mRNA expression and protein levels of AKR1B1 (<b>C</b> and <b>D</b>, respectively) and mRNA expression of <i>AKR1C3</i> (<b>E</b>) in subcutaneous and omental preadipocytes (n = 4) stimulated for 24 h with 1 ng/ml TNF-α, 1 ng/ml IL-1β or both. The data are presented as mean ± SEM (* p≤0.05 for treatment effect in panels A, B, C and D). Expression levels relative to G6PD mRNA expression. The western blot data were quantified by densitometric analysis and values were normalized to β-tubulin.</p

Pearson correlation coefficients of plasma Lf and anthropometric with biochemical parameters in lean to moderately obese women.

<p>Pearson correlation coefficients of plasma Lf and anthropometric with biochemical parameters in lean to moderately obese women.</p