Fermi edge singularities in X-ray spectra of strongly correlated fermions

We discuss the problem of the X-ray absorption in a system of interacting fermions and, in particular, those features in the X-ray spectra that can be used to discriminate between conventional Fermi-liquids and novel "strange metals". Focusing on the case of purely forward scattering off the core-hole potential, we account for the relevant interactions in the conduction band by means of the bosonization technique. We find that the X-ray Fermi edge singularities can still be present, although modified, even if the density of states vanishes at the Fermi energy, and that, in general, the relationship between the two appears to be quite subtle.Comment: Latex, 16 pages, Princeton preprin

Dual-energy X-ray absorptiometry scans accurately predict differing body fat content in live sheep

Background There is considerable interest in implementing mobile scanning technology for on-farm body composition analysis on live animals. These experiments evaluated the use of dual energy X-ray absorptiometry (DXA) as an accurate method of total body fat measurement in live sheep. Results In Exp. 1, visceral and whole body fat analysis was undertaken in sheep with body condition scores (BCS) in the range 2 to 3.25 (scale 1: thin to 5: fat). The relationship of BCS was moderately correlated with visceral fat depot mass (r = 0.59, P  0.05, n = 9). There was a moderate correlation between DXA body fat and BCS (r = 0.70, P < 0.01, n = 17), and DXA body fat was highly correlated with chemical body fat (r = 0.81, P < 0.001, n = 9). In Exp. 3, a series of five DXA scans, at 8-week intervals, was performed on growing sheep over a 32-week period. The average BCS ranged from 2.39 ± 0.07 (S.E.M.) to 3.05 ± 0.11 and the DXA body fat (%) ranged from 16.8 ± 0.8 to 24.2 ± 1.2. There was a moderate correlation between DXA body fat and BCS over the 32 weeks (r = 0.61, P < 0.001, n = 24). Conclusions Overall, these experiments indicated that there was good agreement between BCS, DXA and chemical analysis for measuring total body fat in sheep, and that DXA scanning is a valid method for longitudinal measurement of total body fat in live sheep

Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance

Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess their efficacy in the context of widespread resistance to conventional agents. In the 1970s, much work was performed on the development of peptide mimetics, exemplified by the phosphonopeptide, alafosfalin. We investigated the activity of alafosfalin, di-alanyl fosfalin and β-chloro-L-alanyl-β-chloro-L-alanine against 297 bacterial isolates, including carbapenemase-producing Enterobacterales (CPE) (n = 128), methicillin-resistant Staphylococcus aureus (MRSA) (n = 37) and glycopeptide-resistant enterococci (GRE) (n = 43). The interaction of alafosfalin with meropenem was also examined against 20 isolates of CPE. The MIC50 and MIC90 of alafosfalin for CPE were 1 mg/L and 4 mg/L, respectively and alafosfalin acted synergistically when combined with meropenem against 16 of 20 isolates of CPE. Di-alanyl fosfalin showed potent activity against glycopeptide-resistant isolates of Enterococcus faecalis (MIC90; 0.5 mg/L) and Enterococcus faecium (MIC90; 2 mg/L). Alafosfalin was only moderately active against MRSA (MIC90; 8 mg/L), whereas β-chloro-L-alanyl-β-chloro-L-alanine was slightly more active (MIC90; 4 mg/L). This study shows that phosphonopeptides, including alafosfalin, may have a therapeutic role to play in an era of increasing antibacterial resistance

Long-Term Protection from Bovine Viral Diarrhea Virus in Feedlot Cattle

Bovine viral diarrhea virus (BVDV) causes respiratory and reproductive disease. The duration of immunity of an inactivated vaccine (Virashield 5: Grand Laboratories, Freeman, SD) was measured in two challenge studies. In both studies the vaccinated animals demonstrated fewer clinical signs when challenged with Type II BVDV at 11 or 13 months post vaccination. These results indicate that an inactivated vaccine administered properly can protect animals against disease up to at least a year post vaccination

J1−J2J_1-J_2 quantum Heisenberg antiferromagnet on the triangular lattice: a group symmetry analysis of order by disorder

On the triangular lattice, for $J_2/J_1$ between $1/8$ and $1$, the classical Heisenberg model with first and second neighbor interactions presents four-sublattice ordered ground-states. Spin-wave calculations of Chubukov and Jolicoeur\cite{cj92} and Korshunov\cite{k93} suggest that quantum fluctuations select amongst these states a colinear two-sublattice order. From theoretical requirements, we develop the full symmetry analysis of the low lying levels of the spin-1/2 Hamiltonian in the hypotheses of either a four or a two-sublattice order. We show on the exact spectra of periodic samples ($N=12,16$ and $28$) how quantum fluctuations select the colinear order from the four-sublattice order.Comment: 15 pages, 4 figures (available upon request), Revte

Resonant tunneling and the multichannel Kondo problem: the quantum Brownian motion description

We study mesoscopic resonant tunneling as well as multichannel Kondo problems by mapping them to a first-quantized quantum mechanical model of a particle moving in a multi-dimensional periodic potential with Ohmic dissipation. From a renormalization group analysis, we obtain phase diagrams of the quantum Brownian motion model with various lattice symmetries. For a symmorphic lattice, there are two phases at T=0: a localized phase in which the particle is trapped in a potential minimum, and a free phase in which the particle is unaffected by the periodic potential. For a non-symmorphic lattice, however, there may be an additional intermediate phase in which the particle is neither localized nor completely free. The fixed point governing the intermediate phase is shown to be identical to the well-known multichannel Kondo fixed point in the Toulouse limit as well as the resonance fixed point of a quantum dot model and a double-barrier Luttinger liquid model. The mapping allows us to compute the fixed-poing mobility $\mu^*$ of the quantum Brownian motion model exactly, using known conformal-field-theory results of the Kondo problem. From the mobility, we find that the peak value of the conductance resonance of a spin-1/2 quantum dot problem is given by $e^2/2h$. The scaling form of the resonance line shape is predicted

Time-frequency detection algorithm for gravitational wave bursts

An efficient algorithm is presented for the identification of short bursts of gravitational radiation in the data from broad-band interferometric detectors. The algorithm consists of three steps: pixels of the time-frequency representation of the data that have power above a fixed threshold are first identified. Clusters of such pixels that conform to a set of rules on their size and their proximity to other clusters are formed, and a final threshold is applied on the power integrated over all pixels in such clusters. Formal arguments are given to support the conjecture that this algorithm is very efficient for a wide class of signals. A precise model for the false alarm rate of this algorithm is presented, and it is shown using a number of representative numerical simulations to be accurate at the 1% level for most values of the parameters, with maximal error around 10%.Comment: 26 pages, 15 figures, to appear in PR

Exact perturbative solution of the Kondo problem

We explicitly evaluate the infinite series of integrals that appears in the "Anderson-Yuval" reformulation of the anisotropic Kondo problem in terms of a one-dimensional Coulomb gas. We do this by developing a general approach relating the anisotropic Kondo problem of arbitrary spin with the boundary sine-Gordon model, which describes impurity tunneling in a Luttinger liquid and in the fractional quantum Hall effect. The Kondo solution then follows from the exact perturbative solution of the latter model in terms of Jack polynomials.Comment: 4 pages in revtex two-colum

Expressions of climate perturbations in western Ugandan crater lake sediment records during the last 1000 yr

Equatorial East Africa has a complex, regional patchwork of climate regimes, with multiple interacting drivers. Recent studies have focussed on large lakes and reveal signals that are smoothed in both space and time, and, whilst useful at a continental scale, are of less relevance when understanding short-term, abrupt or immediate impacts of climate and environmental changes. Smaller-scale studies have highlighted spatial complexity and regional heterogeneity of tropical palaeoenvironments in terms of responses to climatic forcing (e.g. the Little Ice Age [LIA]) and questions remain over the spatial extent and synchroneity of climatic changes seen in East African records. Sediment cores from paired crater lakes in western Uganda were examined to assess ecosystem response to long-term climate and environmental change as well as testing responses to multiple drivers using redundancy analysis. These archives provide annual to sub-decadal records of environmental change. The records from the two lakes demonstrate an individualistic response to external (e.g. climatic) drivers, however, some of the broader patterns observed across East Africa suggest that the lakes are indeed sensitive to climatic perturbations such as a dry Mediaeval Climate Anomaly (MCA; 1000–1200 AD) and a relatively drier climate during the main phase of the LIA (1500–1800 AD); though lake levels in western Uganda do fluctuate. The relationship of Ugandan lakes to regional climate drivers breaks down c. 1800 AD, when major changes in the ecosystems appear to be a response to sediment and nutrient influxes as a result of increasing cultural impacts within the lake catchments. The data highlight the complexity of individual lake response to climate forcing, indicating shifting drivers through time. This research also highlights the importance of using multi-lake studies within a landscape to allow for rigorous testing of climate reconstructions, forcing and ecosystem response